DeBakey Cardiovascular Magnetic Resonance Study

Purpose

While advancements in cardiac magnetic resonance (CMR) have improved image quality, it is unclear how these improvements are connected to the clinical evaluation of individuals with cardiovascular disease. The aim of this large prospective registry revolves around 4 key principles: 1) utilize CMR to gain additional pathophysiologic insights into cardiovascular disease, 2) understand how CMR compares to alternative cardiovascular diagnostic modalities, 3) determine how CMR affects clinical management decisions, and 4) establish a link between CMR findings and long term prognosis in patients with known or suspected cardiovascular disease. The ultimate aim is to utilize CMR to improve patient outcomes. CMR techniques to be studies include function, fibrosis, and flow. Focus areas include valvular heart disease, ischemic heart disease, cardiomyopathies, and vascular disease.

Condition

  • Cardiovascular Diseases

Eligibility

Eligible Ages
All ages
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • All patients presenting to the Houston Methodist CMR Laboratory with known or suspected cardiovascular disease.

Exclusion Criteria

  • Unable to provide informed consent

Study Design

Phase
Study Type
Observational [Patient Registry]
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Cardiovascular Magnetic Resonance All patients who present to the Houston Methodist CMR Laboratory
  • Diagnostic Test: Cardiovascular Magnetic Resonance
    Patients will undergo various CMR techniques designed to assess cardiovascular structure and function, tissue characteristics, and flow.

Recruiting Locations

Houston Methodist Hospital
Houston 4699066, Texas 4736286 77030
Contact:
Rachel Kronman-Gross, BS
713-441-6539
rkronman-gross@houstonmethodist.org

More Details

Status
Recruiting
Sponsor
Dipan Shah

Study Contact

Rachel Kronman-Gross, BS
7134416539
rkronman-gross@houstonmethodist.org

Detailed Description

Patient Population, Recruitment, and Consent: Patients presenting to the Houston Methodist DeBakey CMR Laboratory will be enrolled from April 2008 to April 2038. It is expected that up to 100,000 patients may be enrolled during this period. Subjects will be identified based on their referral to the Houston Methodist DeBakey CMR Laboratory for MRI studies during the proposed study period. After enrollment, a registered nurse or physician will perform a thorough structured patient interview and/or review of electronic health records to document baseline medical history including cardiac risk factors, symptoms, medication usage, and prior procedure history. A small blood sample will be drawn and stored for future biomarker and/or genetic testing analysis. Annual follow up for clinical status will be performed via review of electronic health records; structured telephone interviews with the patients, relatives, and/or their health care providers; and/or the social security death index database.