Continuous Glucose Monitoring in Infants

Purpose

The purpose of this study is to employ continuous glucose monitoring to measure glucose profiles in newborn infants.

Condition

  • Neonatal Hypoglycemia

Eligibility

Eligible Ages
Between 1 Hour and 2 Hours
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Mother at least 18 years of age - Infants born either appropriate for gestational age (AGA) or large for gestational age (LGA) - Skin fold over superior gluteus area at least 1 inch in thickness as measured by skin calipers

Exclusion Criteria

  • Infants born small for gestational age (SGA) - Infant birth weight <2.5 kg - Infant BMI <10th percentile on Olsen chart - Infants born <38 weeks gestation - Infants with concern for intrauterine growth restriction (IUGR) and short femur length based on ultrasound - Mother is non-English speaking

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
No increased risk of hypoglycemia Infants born with no obvious risk factors for hypoglycemia in the neonatal period.
  • Device: Dexcom continuous glucose monitor
    Measurement of interstitial glucose
Increased risk of hypoglycemia Infants considered at increased risk for hypoglycemia after birth including the following criteria: - Infant born to a diabetic mother - Very large for gestational age (VLGA) infant with weight >97%
  • Device: Dexcom continuous glucose monitor
    Measurement of interstitial glucose

Recruiting Locations

UCSD Medical Center
La Jolla, California 92037
Contact:
Valentina Stanley, BS
858-966-4032
vstanley@health.ucsd.edu

More Details

Status
Recruiting
Sponsor
University of California, San Diego

Study Contact

Valentina Stanley, BS
(858) 249-5985
vstanley@health.ucsd.edu

Detailed Description

We will place a continuous glucose monitor on the infant within 2 hours of birth and record blood glucose values every 5 minutes via the monitor; in addition, the infant will receive blood glucose checks via heel stick according to the standard hospital glucose monitoring protocol.