Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders

Purpose

The proposed study tests fear, gut peptide response, and perceptions of fullness as causes of gastrointestinal distress and eating disorder maintenance.

Condition

  • Feeding and Eating Disorders

Eligibility

Eligible Ages
Between 18 Years and 40 Years
Eligible Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • female - DSM-5 eating disorder - score 16 or higher on the Clinical Impairment Assessment - experience nausea or stomachache after eating at least "sometimes" - 18 to 40 years old - body mass index between 18.5 and 26.5 kg/m2

Exclusion Criteria

  • medical conditions affect appetite or weight - Recent pregnancy or current breastfeeding - Dairy, strawberry or honey food allergy - Specific phobia, blood-injection-injury type

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover Assignment
Primary Purpose
Basic Science
Masking
Single (Participant)

Arm Groups

ArmDescriptionAssigned Intervention
Other
High Fat Yogurt - Low Fat Yogurt
Participants will eat yogurt described as 'high fat' at Study Visit 2 and yogurt described as 'low fat' at Study Visit 3.
  • Other: Test meal description changed
    Using a within-subjects crossover design, on two separate mornings participants will eat yogurt described as 'high fat' and 'low fat.' In actuality, the meals will not differ.
Other
Low Fat Yogurt - High Fat Yogurt
Participants will eat yogurt described as 'low fat' at Study Visit 2 and yogurt described as 'high fat' at Study Visit 3.
  • Other: Test meal description changed
    Using a within-subjects crossover design, on two separate mornings participants will eat yogurt described as 'high fat' and 'low fat.' In actuality, the meals will not differ.

Recruiting Locations

Ohio University
Athens 4505542, Ohio 5165418 45701
Contact:
Katherine J Forney, PhD

More Details

Status
Recruiting
Sponsor
Ohio University

Study Contact

Katherine J Forney, PhD
740-593-1085
forney@ohio.edu