Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

Purpose

The purpose of this study is to find out if fluid rinsed from peoples' airways (bronchial washing samples) during routine surgery to remove (resect) their non-small cell lung cancer (NSCLC) tumors contains enough vesicles to do testing that may help the researchers learn more about their NSCLC.

Condition

  • Non-Small Cell Lung Cancer

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • All patients ≥ 18 years of age undergoing consideration of surgical resection, including lobar resections, sublobar resections, and pneumonectomies, for primary lung cancer will be eligible. - Patients with previously resected disease and/or previous radiation therapy will be considered on a case by case basis.

Exclusion Criteria

  • Patients with active infection or pneumonia which may impact exosome makeup - Additionally, if at the discretion of the operating surgeon, obtaining bronchial washings would lead to undue morbidity, the patient would be excluded and replaced

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Recruiting Locations

Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey 07920
Contact:
David Jones, MD
212-639-6428

Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey 07748
Contact:
David Jones, MD
212-639-6428

Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey 07645
Contact:
David Jones, MD
212-639-6428

Memorial Sloan Kettering Suffolk - Commack (Consent Only)
Commack, New York 11725
Contact:
David Jones, MD
212-639-6428

Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York 10604
Contact:
David Jones, MD
212-639-6428

Memorial Sloan Kettering Cancer Center
New York, New York 10065
Contact:
David Jones, MD
212-639-6428

Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York 11553
Contact:
David Jones, MD
212-639-6428

More Details

Status
Recruiting
Sponsor
Memorial Sloan Kettering Cancer Center

Study Contact

David Jones, MD
212-639-6428
jonesd2@mskcc.org