mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Purpose

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.

Conditions

  • Advanced Esophageal Adenocarcinoma
  • Advanced Gastric Adenocarcinoma
  • Advanced Gastroesophageal Junction Adenocarcinoma
  • Clinical Stage III Esophageal Adenocarcinoma AJCC v8
  • Clinical Stage III Gastric Cancer AJCC v8
  • Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
  • Clinical Stage IV Gastric Cancer AJCC v8
  • Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
  • Metastatic Esophageal Adenocarcinoma
  • Metastatic Gastric Adenocarcinoma
  • Metastatic Gastroesophageal Junction Adenocarcinoma
  • Unresectable Esophageal Adenocarcinoma
  • Unresectable Gastric Adenocarcinoma
  • Unresectable Gastroesophageal Junction Adenocarcinoma

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Histologic documentation: HER2 negative adenocarcinoma as defined by American Society of Clinical Oncology (ASCO) College of American Pathologists (CAP) guidelines (Bartley et al., Journal of Clinical Oncology [JCO] 2017) with known PD-L1 CPS (Any CPS is allowed, but should be known prior to registration) - Stage: unresectable or metastatic - Tumor site: esophagus, gastroesophageal junction, or stomach - Measurable disease or non-measurable but evaluable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 - No prior treatment for unresectable or metastatic disease - Prior neoadjuvant or adjuvant cytotoxic chemotherapy or adjuvant immunotherapy is allowed as long as it was completed at least 1 year prior to registration - Age >= 18 years - Eastern Cooperative Oncology Group (ECOG) Performance Status 0 or 1 - Absolute neutrophil count (ANC) >= 1,500/mm^3 - Platelet count >= 100,000/mm^3 - Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min - Total bilirubin =< 1.5 x ULN - Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3 x ULN (in patients with liver metastasis: =< 5 x ULN if clearly attributable to liver metastases) - Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial - Patients positive for human immunodeficiency virus (HIV) are eligible only if they meet all of the following: - On effective anti-retroviral therapy - Undetectable HIV viral load by standard clinical assay =< 6 months of registration - Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better - Patients who will receive nivolumab in addition to chemotherapy must not have any contraindications to immune checkpoint inhibitors - Patients must not have active autoimmune disease that has required systemic treatment within 6 months prior to registration. Patients are permitted to receive immunotherapy if they have vitiligo, type I diabetes, residual hypothyroidism due to autoimmune condition only requiring hormone replacement, psoriasis not requiring systemic treatment, or conditions not expected to recur in the absence of an external trigger (precipitating event) - Patients must not have a condition requiring systemic treatment with either corticosteroids (>10mg/day prednisone equivalents) or other immunosuppressive medications within 14 days prior to registration. Inhaled or topical steroids and adrenal replacement doses (=< 10mg/day prednisone equivalent) are permitted - Patients must not have a history of noninfectious pneumonitis requiring steroids - Patients with prior immune mediated adverse events related to immunotherapy that resulted in permanent treatment discontinuation with these agents are ineligible - This study includes the use of the mandatory patient completed measure, PRO-CTCAE. For this study the PRO-CTCAE is available in English, Spanish, Korean, Chinese (Simplified), and Russian, hence patients must be able to speak, understand and read in these languages. Ad-hoc translation of patient-reported measures is not permitted

Exclusion Criteria

  • Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects * Therefore, for women of childbearing potential only, a negative serum or urine pregnancy test done =< 7 days prior to registration is required - No known Gilbert's syndrome or known homozygosity for UGAT1A1*28 polymorphism - No baseline grade >= 2 peripheral neuropathy, neurosensory toxicity, or neuromotor toxicity per CTCAE version (v) 5.0 regardless of causality - No medical condition such as uncontrolled infection or uncontrolled diabetes mellitus which, in the opinion of the treating physician, would make this protocol unreasonably hazardous for the patient - No untreated, symptomatic brain metastasis. Patients with treated brain metastases are eligible if the following criteria are met: 1) follow-up brain imaging done at least in 4 weeks after central nervous system (CNS)-directed therapy shows no evidence of progression and 2) the patient no longer requires steroids, or is on a stable steroid dose for more than four weeks - No allogeneic tissue/organ transplant

Study Design

Phase
Phase 3
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Arm I (mFOLFIRINOX, nivolumab) 		Patients receive fluorouracil IV, leucovorin calcium IV, oxaliplatin IV, and irinotecan IV on study and nivolumab IV as clinically indicated. Patients undergo MRI and a CT scan throughout the trial. Patients may also undergo blood sample collection on study.
  • Drug: Fluorouracil
    Given IV
    Other names:
    • 2,4-Dioxo-5-fluoropyrimidine
    • 5 Fluorouracil
    • 5 Fluorouracilum
    • 5 FU
    • 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluoro-2,4(1H,3H)-pyrimidinedione,
  • Drug: Leucovorin Calcium
    Given IV
    Other names:
    • 1492-18-8
    • 5-Formyl Tetrahydrofolate
    • Calcium (6S)-Folinate
    • Calcium Folinate
  • Drug: Oxaliplatin
    Given IV
    Other names:
    • 1-OHP
    • Dacotin
    • Dacplat
    • ELOXATIN
  • Drug: Irinotecan
    Given IV
  • Biological: Nivolumab
    Given IV
    Other names:
    • MDX-1106
    • Opdivo
  • Procedure: Magnetic Resonance Imaging
    Undergo MRI
    Other names:
    • MRI
  • Procedure: Computed Tomography
    Undergo a CT Scan
    Other names:
    • CAT Scan
    • Computed Axial Tomography
    • CT Scan
  • Procedure: Biospecimen Collection
    Undergo blood sample collection
  • Other: Questionnaire Administration
    Ancillary studies
Active Comparator
Arm II (mFOLFOX, nivolumab) 		Patients receive fluorouracil IV, leucovorin calcium IV, and oxaliplatin IV on study and nivolumab IV as clinically indicated. Patients undergo MRI and a CT scan throughout the trial. Patients may also undergo blood sample collection on study.
  • Drug: Fluorouracil
    Given IV
    Other names:
    • 2,4-Dioxo-5-fluoropyrimidine
    • 5 Fluorouracil
    • 5 Fluorouracilum
    • 5 FU
    • 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluoro-2,4(1H,3H)-pyrimidinedione,
  • Drug: Leucovorin Calcium
    Given IV
    Other names:
    • 1492-18-8
    • 5-Formyl Tetrahydrofolate
    • Calcium (6S)-Folinate
    • Calcium Folinate
  • Drug: Oxaliplatin
    Given IV
    Other names:
    • 1-OHP
    • Dacotin
    • Dacplat
    • ELOXATIN
  • Biological: Nivolumab
    Given IV
    Other names:
    • MDX-1106
    • Opdivo
  • Procedure: Magnetic Resonance Imaging
    Undergo MRI
    Other names:
    • MRI
  • Procedure: Computed Tomography
    Undergo a CT Scan
    Other names:
    • CAT Scan
    • Computed Axial Tomography
    • CT Scan
  • Procedure: Biospecimen Collection
    Undergo blood sample collection
  • Other: Questionnaire Administration
    Ancillary studies

Recruiting Locations

University of Alabama at Birmingham Cancer Center
Birmingham 4049979, Alabama 4829764 35233
Contact:
Site Public Contact
gingerreeves@uabmc.edu

Anchorage Associates in Radiation Medicine
Anchorage 5879400, Alaska 5879092 98508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Breast Care and Surgery LLC
Anchorage 5879400, Alaska 5879092 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Oncology and Hematology LLC
Anchorage 5879400, Alaska 5879092 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Women's Cancer Care
Anchorage 5879400, Alaska 5879092 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Katmai Oncology Group
Anchorage 5879400, Alaska 5879092 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Providence Alaska Medical Center
Anchorage 5879400, Alaska 5879092 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Kingman Regional Medical Center
Kingman 5301067, Arizona 5551752 86401
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Mercy Hospital Fort Smith
Fort Smith 4111410, Arkansas 4099753 72903
Contact:
Site Public Contact
800-378-9373

CARTI Cancer Center
Little Rock 4119403, Arkansas 4099753 72205
Contact:
Site Public Contact
501-906-4199
Research@CARTI.com

Kaiser Permanente-Deer Valley Medical Center
Antioch 5324200, California 5332921 94531
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

PCR Oncology
Arroyo Grande 5324802, California 5332921 93420
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Sutter Auburn Faith Hospital
Auburn 5325223, California 5332921 95602
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn 5325223, California 5332921 95603
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Alta Bates Summit Medical Center-Herrick Campus
Berkeley 5327684, California 5332921 94704
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank 5331835, California 5332921 91505
Contact:
Site Public Contact
818-847-4793
Najee.Boucher@providence.org

Mills-Peninsula Medical Center
Burlingame 5331920, California 5332921 94010
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park 5333282, California 5332921 95682
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Eden Hospital Medical Center
Castro Valley 5334928, California 5332921 94546
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

UC Irvine Health Cancer Center-Newport
Costa Mesa 5339840, California 5332921 92627
Contact:
Site Public Contact
877-827-8839

Sutter Davis Hospital
Davis 5341704, California 5332921 95616
Contact:
Site Public Contact
NCIclinicaltrials@sutterhealth.org

Kaiser Permanente Dublin
Dublin 5344157, California 5332921 94568
Contact:
Site Public Contact
877-642-4691

Kaiser Permanente-Fremont
Fremont 5350734, California 5332921 94538
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Palo Alto Medical Foundation-Fremont
Fremont 5350734, California 5332921 94538
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Fresno Cancer Center
Fresno 5350937, California 5332921 93720
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Fresno Orchard Plaza
Fresno 5350937, California 5332921 93720
Contact:
Site Public Contact
833-574-2273

Kaiser Permanente-Fresno
Fresno 5350937, California 5332921 93720
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine 5359777, California 5332921 92612
Contact:
Site Public Contact
877-827-8839
ucstudy@uci.edu

Keck Medicine of USC Koreatown
Los Angeles 5368361, California 5332921 90020
Contact:
Site Public Contact
213-388-0908

Los Angeles General Medical Center
Los Angeles 5368361, California 5332921 90033
Contact:
Site Public Contact
323-865-0451
uscnorrisinfo@med.usc.edu

USC / Norris Comprehensive Cancer Center
Los Angeles 5368361, California 5332921 90033
Contact:
Site Public Contact
323-865-0451

Memorial Medical Center
Modesto 5373900, California 5332921 95355
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente- Modesto MOB II
Modesto 5373900, California 5332921 95356
Contact:
Site Public Contact
877-642-4691

Kaiser Permanente-Modesto
Modesto 5373900, California 5332921 95356
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Palo Alto Medical Foundation-Camino Division
Mountain View 5375480, California 5332921 94040
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View 5375480, California 5332921 94040
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Providence Queen of The Valley
Napa 5376095, California 5332921 94558
Contact:
Site Public Contact
707-521-3830

USC Norris Oncology/Hematology-Newport Beach
Newport Beach 5376890, California 5332921 92663
Contact:
Site Public Contact
323-865-0451

Sutter Cancer Research Consortium
Novato 5378044, California 5332921 94945
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente Oakland-Broadway
Oakland 5378538, California 5332921 94611
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Oakland
Oakland 5378538, California 5332921 94611
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange 5379513, California 5332921 92868
Contact:
Site Public Contact
877-827-8839
ucstudy@uci.edu

Palo Alto Medical Foundation Health Care
Palo Alto 5380748, California 5332921 94301
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente-Rancho Cordova Cancer Center
Rancho Cordova 5385941, California 5332921 95670
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Eisenhower Medical Center
Rancho Mirage 5386015, California 5332921 92270
Contact:
Site Public Contact
760-834-3798

Kaiser Permanente- Marshall Medical Offices
Redwood City 5386834, California 5332921 94063
Contact:
Site Public Contact
877-642-4691

Kaiser Permanente-Richmond
Richmond 5387428, California 5332921 94801
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Rohnert Park Cancer Center
Rohnert Park 5388564, California 5332921 94928
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Roseville
Roseville 5388881, California 5332921 95661
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville 5388881, California 5332921 95661
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Sutter Roseville Medical Center
Roseville 5388881, California 5332921 95661
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

The Permanente Medical Group-Roseville Radiation Oncology
Roseville 5388881, California 5332921 95678
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Downtown Commons
Sacramento 5389489, California 5332921 95814
Contact:
Site Public Contact
877-642-4691
kpoct@kp.org

Sutter Medical Center Sacramento
Sacramento 5389489, California 5332921 95816
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente-South Sacramento
Sacramento 5389489, California 5332921 95823
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

South Sacramento Cancer Center
Sacramento 5389489, California 5332921 95823
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

California Pacific Medical Center-Pacific Campus
San Francisco 5391959, California 5332921 94115
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente-San Francisco
San Francisco 5391959, California 5332921 94115
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Santa Teresa-San Jose
San Jose 5392171, California 5332921 95119
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente San Leandro
San Leandro 5392263, California 5332921 94577
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Mills Health Center
San Mateo 5392423, California 5332921 94401
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser San Rafael-Gallinas
San Rafael 5392567, California 5332921 94903
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Ridley-Tree Cancer Center
Santa Barbara 5392952, California 5332921 93105
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente Medical Center - Santa Clara
Santa Clara 5393015, California 5332921 95051
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Palo Alto Medical Foundation-Santa Cruz
Santa Cruz 5393052, California 5332921 95065
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Santa Cruz Radiation Oncology Medical Group
Santa Cruz 5393052, California 5332921 95065
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente-Santa Rosa
Santa Rosa 5393287, California 5332921 95403
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Providence Medical Foundation - Santa Rosa
Santa Rosa 5393287, California 5332921 95403
Contact:
Site Public Contact
707-521-3830

Sutter Pacific Medical Foundation
Santa Rosa 5393287, California 5332921 95403
Contact:
Site Public Contact
415-209-2683
clinicalresearch@sutterhealth.org

Providence Santa Rosa Memorial Hospital
Santa Rosa 5393287, California 5332921 95405
Contact:
Site Public Contact
707-521-3830

Kaiser Permanente Cancer Treatment Center
South San Francisco 5397765, California 5332921 94080
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-South San Francisco
South San Francisco 5397765, California 5332921 94080
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Stockton
Stockton 5399020, California 5332921 95210
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Palo Alto Medical Foundation-Sunnyvale
Sunnyvale 5400075, California 5332921 94086
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente Medical Center-Vacaville
Vacaville 5405228, California 5332921 95688
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Vallejo
Vallejo 5405380, California 5332921 94589
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Sutter Solano Medical Center/Cancer Center
Vallejo 5405380, California 5332921 94589
Contact:
Site Public Contact
clinicalresearch@sutterhealth.org

Kaiser Permanente-Walnut Creek
Walnut Creek 5406990, California 5332921 94596
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Intermountain Health Platte Valley Hospital
Brighton 5414941, Colorado 5417618 80601
Contact:
Site Public Contact
peaksresearch@imail.org

Cancer Center of Colorado at Sloan's Lake
Denver 5419384, Colorado 5417618 80204
Contact:
Site Public Contact
303-777-2663

National Jewish Health-Main Campus
Denver 5419384, Colorado 5417618 80206
Contact:
Site Public Contact
877-225-5654
glicht@co-cancerresearch.org

AdventHealth Porter
Denver 5419384, Colorado 5417618 80210
Contact:
Site Public Contact
research.institute@adventhealth.com

Saint Joseph Hospital - Cancer Centers of Colorado
Denver 5419384, Colorado 5417618 80218
Contact:
Site Public Contact
303-318-3413

Poudre Valley Hospital
Fort Collins 5577147, Colorado 5417618 80524
Contact:
Site Public Contact
970-297-6150

Cancer Care and Hematology-Fort Collins
Fort Collins 5577147, Colorado 5417618 80528
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Lutheran Hospital - Cancer Centers of Colorado
Golden 5423294, Colorado 5417618 80401
Contact:
Site Public Contact
peaksresearch@imail.org

National Jewish Health-Western Hematology Oncology
Golden 5423294, Colorado 5417618 80401
Contact:
Site Public Contact
303-777-2663
glicht@co-cancerresearch.org

Saint Mary's Hospital and Regional Medical Center
Grand Junction 5423573, Colorado 5417618 81501
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

UCHealth Greeley Hospital
Greeley 5577592, Colorado 5417618 80631
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Good Samaritan Hospital - Cancer Centers of Colorado
Lafayette 5427771, Colorado 5417618 80026
Contact:
Site Public Contact
peaksresearch@imail.org

Medical Center of the Rockies
Loveland 5579368, Colorado 5417618 80538
Contact:
Site Public Contact
970-203-7083

AdventHealth Parker
Parker 5434006, Colorado 5417618 80138
Contact:
Site Public Contact
research.institute@adventhealth.com

National Jewish Health-Northern Hematology Oncology
Thornton 5441492, Colorado 5417618 80260
Contact:
Site Public Contact
303-777-2663
glicht@co-cancerresearch.org

Intermountain Health Lutheran Hospital
Wheat Ridge 5443948, Colorado 5417618 80401
Contact:
Site Public Contact
peaksresearch@imail.org

Hartford HealthCare - Avon
Avon 5281730, Connecticut 4831725 06001
Contact:
Site Public Contact
860-972-4700

Hartford Hospital
Hartford 4835797, Connecticut 4831725 06102
Contact:
Site Public Contact
860-545-5363

Hartford HealthCare - Manchester
Manchester 4838174, Connecticut 4831725 06042
Contact:
Site Public Contact
860-972-4700

Midstate Medical Center
Meriden 4838524, Connecticut 4831725 06451
Contact:
Site Public Contact
866-662-5678

The Hospital of Central Connecticut
New Britain 4839292, Connecticut 4831725 06050
Contact:
Site Public Contact
860-224-5660

Beebe Medical Center
Lewes 4143354, Delaware 4142224 19958
Contact:
Site Public Contact
302-291-6730
research@beebehealthcare.org

Beebe South Coastal Health Campus
Millville 4143696, Delaware 4142224 19967
Contact:
Site Public Contact
302-291-6730
research@beebehealthcare.org

Helen F Graham Cancer Center
Newark 4143861, Delaware 4142224 19713
Contact:
Site Public Contact
302-623-4450
lbarone@christianacare.org

Medical Oncology Hematology Consultants PA
Newark 4143861, Delaware 4142224 19713
Contact:
Site Public Contact
302-623-4450
lbarone@christianacare.org

Christiana Care Health System-Christiana Hospital
Newark 4143861, Delaware 4142224 19718
Contact:
Site Public Contact
302-623-4450
lbarone@christianacare.org

Beebe Health Campus
Rehoboth Beach 4144284, Delaware 4142224 19971
Contact:
Site Public Contact
302-291-6730
research@beebehealthcare.org

Christiana Care Health System-Wilmington Hospital
Wilmington 4145381, Delaware 4142224 19801
Contact:
Site Public Contact
302-623-4450
lbarone@christianacare.org

MedStar Georgetown University Hospital
Washington D.C. 4140963, District of Columbia 4138106 20007
Contact:
Site Public Contact
202-444-2223

George Washington University Medical Center
Washington D.C. 4140963, District of Columbia 4138106 20037
Contact:
Site Public Contact
202-741-2210

Schulze Family Foundation Cancer Clinic - Bonita Health Center
Bonita Springs 4148533, Florida 4155751 34135
Contact:
Site Public Contact
239-343-9660
RCCR@leehealth.org

Holy Cross Hospital
Fort Lauderdale 4155966, Florida 4155751 33308
Contact:
Site Public Contact
eileen.georgi@holy-cross.com

Regional Cancer Center-Lee Memorial Health System
Fort Myers 4155995, Florida 4155751 33905
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood 4158928, Florida 4155751 33021
Contact:
Site Public Contact
954-265-1847
OHR@mhs.net

Jupiter Medical Center
Jupiter 4160610, Florida 4155751 33458
Contact:
Site Public Contact
561-263-5791
clinicaltrials@jupitermed.com

Memorial Hospital West
Pembroke Pines 4168139, Florida 4155751 33028
Contact:
Site Public Contact
954-265-4325

Tift Regional Medical Center
Tifton 4226552, Georgia 4197000 31794
Contact:
Site Public Contact
800-648-1935

Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu 5856195, Hawaii 5855797 96813
Contact:
Site Public Contact
808-524-6115
i.webster@hawaiicancercare.com

Queen's Cancer Cenrer - POB I
Honolulu 5856195, Hawaii 5855797 96813
Contact:
Site Public Contact
808-532-0315

Queen's Medical Center
Honolulu 5856195, Hawaii 5855797 96813
Contact:
Site Public Contact
808-545-8548

Straub Clinic and Hospital
Honolulu 5856195, Hawaii 5855797 96813
Contact:
Site Public Contact
808-522-4333

Queen's Cancer Center - Kuakini
Honolulu 5856195, Hawaii 5855797 96817
Contact:
Site Public Contact
808-531-8521

Kaiser Permanente Moanalua Medical Center
Honolulu 5856195, Hawaii 5855797 96819
Contact:
Site Public Contact
808-432-5195
shelley.a.clark@kp.org

Straub Medical Center - Kahului Clinic
Kahului 5847411, Hawaii 5855797 96732
Contact:
Site Public Contact
lori.kam@hawaiipacifichealth.org

Hawaii Cancer Care - Westridge
‘Aiea 5856430, Hawaii 5855797 96701
Contact:
Site Public Contact
808-539-2273
info@hawaiicancercare.com

Pali Momi Medical Center
‘Aiea 5856430, Hawaii 5855797 96701
Contact:
Site Public Contact
808-486-6000

Queen's Cancer Center - Pearlridge
‘Aiea 5856430, Hawaii 5855797 96701
Contact:
Site Public Contact
808-487-7447

The Queen's Medical Center - West Oahu
‘Ewa Beach 5855051, Hawaii 5855797 96706
Contact:
Site Public Contact
rohta@queens.org

Saint Alphonsus Cancer Care Center-Boise
Boise 5586437, Idaho 5596512 83706
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Saint Luke's Cancer Institute - Boise
Boise 5586437, Idaho 5596512 83712
Contact:
Site Public Contact
208-381-2774
eslinget@slhs.org

Saint Alphonsus Cancer Care Center-Caldwell
Caldwell 5587698, Idaho 5596512 83605
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Kootenai Health - Coeur d'Alene
Coeur d'Alene 5589173, Idaho 5596512 83814
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Luke's Cancer Institute - Fruitland
Fruitland 5593708, Idaho 5596512 83619
Contact:
Site Public Contact
208-381-2774
eslinget@slhs.org

Idaho Urologic Institute-Meridian
Meridian 5600685, Idaho 5596512 83642
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Saint Luke's Cancer Institute - Meridian
Meridian 5600685, Idaho 5596512 83642
Contact:
Site Public Contact
208-381-2774
eslinget@slhs.org

Saint Alphonsus Cancer Care Center-Nampa
Nampa 5601933, Idaho 5596512 83687
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Luke's Cancer Institute - Nampa
Nampa 5601933, Idaho 5596512 83687
Contact:
Site Public Contact
208-381-2774
eslinget@slhs.org

Kootenai Clinic Cancer Services - Post Falls
Post Falls 5604353, Idaho 5596512 83854
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Kootenai Clinic Cancer Services - Sandpoint
Sandpoint 5606401, Idaho 5596512 83864
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Luke's Cancer Institute - Twin Falls
Twin Falls 5610810, Idaho 5596512 83301
Contact:
Site Public Contact
208-381-2774
eslinget@slhs.org

OSF Saint Anthony's Health Center
Alton 4232679, Illinois 4896861 62002
Contact:
Site Public Contact
618-463-5623

Rush-Copley Medical Center
Aurora 4883817, Illinois 4896861 60504
Contact:
Site Public Contact
630-978-6212
RCMC_Cancer_Research@rush.edu

Advocate Outpatient Center - Aurora
Aurora 4883817, Illinois 4896861 60506
Contact:
Site Public Contact
ncorp@aah.org

Advocate Good Shepherd Hospital
Barrington 4884116, Illinois 4896861 60010
Contact:
Site Public Contact
847-842-4847

Illinois CancerCare-Bloomington
Bloomington 4885164, Illinois 4896861 61704
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Canton
Canton 4831990, Illinois 4896861 61520
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Memorial Hospital of Carbondale
Carbondale 4235193, Illinois 4896861 62902
Contact:
Site Public Contact
618-457-5200
clinical.research@sih.net

SIH Cancer Institute
Carterville 4235311, Illinois 4896861 62918
Contact:
Site Public Contact
618-985-3333
clinical.research@sih.net

Illinois CancerCare-Carthage
Carthage 4886716, Illinois 4896861 62321
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Centralia Oncology Clinic
Centralia 4235587, Illinois 4896861 62801
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Mount Sinai Hospital Medical Center
Chicago 4887398, Illinois 4896861 60608
Contact:
Site Public Contact
773-257-5960
suhi@sinai.org

John H Stroger Jr Hospital of Cook County
Chicago 4887398, Illinois 4896861 60612
Contact:
Site Public Contact
312-864-5204

University of Illinois
Chicago 4887398, Illinois 4896861 60612
Contact:
Site Public Contact
312-355-3046

University of Chicago Comprehensive Cancer Center
Chicago 4887398, Illinois 4896861 60637
Contact:
Site Public Contact
773-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Advocate Illinois Masonic Medical Center
Chicago 4887398, Illinois 4896861 60657
Contact:
Site Public Contact
773-296-5360

AMG Crystal Lake - Oncology
Crystal Lake 4889229, Illinois 4896861 60014
Contact:
Site Public Contact
630-929-6129
advocateresearch@advocate.com

Carle at The Riverfront
Danville 4889426, Illinois 4896861 61832
Contact:
Site Public Contact
800-446-5532
Research@Carle.com

Cancer Care Specialists of Illinois - Decatur
Decatur 4236895, Illinois 4896861 62526
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Decatur Memorial Hospital
Decatur 4236895, Illinois 4896861 62526
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Illinois CancerCare-Dixon
Dixon 4889959, Illinois 4896861 61021
Contact:
Site Public Contact
815-285-7800

Advocate Good Samaritan Hospital
Downers Grove 4890119, Illinois 4896861 60515
Contact:
Site Public Contact
630-275-1270
Barbara.barhamand@advocatehealth.com

Carle Physician Group-Effingham
Effingham 4237727, Illinois 4896861 62401
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Crossroads Cancer Center
Effingham 4237727, Illinois 4896861 62401
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Advocate Sherman Hospital
Elgin 4890864, Illinois 4896861 60123
Contact:
Site Public Contact
847-429-2907

Illinois CancerCare-Eureka
Eureka 4891310, Illinois 4896861 61530
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Galesburg
Galesburg 4893392, Illinois 4896861 61401
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Ingalls Memorial Hospital
Harvey 4895298, Illinois 4896861 60426
Contact:
Site Public Contact
708-915-4673
clinicaltrials@ingalls.org

Advocate South Suburban Hospital
Hazel Crest 4895416, Illinois 4896861 60429
Contact:
Site Public Contact
708-799-9995

Illinois CancerCare-Kewanee Clinic
Kewanee 4898433, Illinois 4896861 61443
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

AMG Libertyville - Oncology
Libertyville 4899739, Illinois 4896861 60048
Contact:
Site Public Contact
630-929-6129
advocateresearch@advocatehealth.com

Condell Memorial Hospital
Libertyville 4899739, Illinois 4896861 60048
Contact:
Site Public Contact
630-929-6129
advocateresearch@advocatehealth.com

Illinois CancerCare-Macomb
Macomb 4900817, Illinois 4896861 61455
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Carle Physician Group-Mattoon/Charleston
Mattoon 4244099, Illinois 4896861 61938
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Trinity Medical Center
Moline 4902476, Illinois 4896861 61265
Contact:
Site Public Contact
309-779-2000

SSM Health Good Samaritan
Mount Vernon 4245152, Illinois 4896861 62864
Contact:
Site Public Contact
618-899-1894
gayla.hall@ssmhealth.com

UC Comprehensive Cancer Center at Silver Cross
New Lenox 4903535, Illinois 4896861 60451
Contact:
Site Public Contact
773-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Carle Cancer Institute Normal
Normal 4903780, Illinois 4896861 61761
Contact:
Site Public Contact
800-446-5532
Research@Carle.com

Cancer Care Center of O'Fallon
O'Fallon 4245926, Illinois 4896861 62269
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

HSHS Saint Elizabeth's Hospital
O'Fallon 4245926, Illinois 4896861 62269
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Advocate Christ Medical Center
Oak Lawn 4904365, Illinois 4896861 60453-2699
Contact:
Site Public Contact
800-323-8622

University of Chicago Medicine-Orland Park
Orland Park 4904937, Illinois 4896861 60462
Contact:
Site Public Contact
773-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Illinois CancerCare-Ottawa Clinic
Ottawa 4905006, Illinois 4896861 61350
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Advocate Lutheran General Hospital
Park Ridge 4905367, Illinois 4896861 60068
Contact:
Site Public Contact
847-384-3621

Illinois CancerCare-Pekin
Pekin 4905599, Illinois 4896861 61554
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peoria
Peoria 4905687, Illinois 4896861 61615
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Methodist Medical Center of Illinois
Peoria 4905687, Illinois 4896861 61636
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peru
Peru 4905770, Illinois 4896861 61354
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Valley Radiation Oncology
Peru 4905770, Illinois 4896861 61354
Contact:
Site Public Contact
815-664-4141

Illinois CancerCare-Princeton
Princeton 4906818, Illinois 4896861 61356
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

UW Health Carbone Cancer Center Rockford
Rockford 4907959, Illinois 4896861 61114
Contact:
Site Public Contact
779-696-9378
lkline@uwhealth.org

Southern Illinois University School of Medicine
Springfield 4250542, Illinois 4896861 62702
Contact:
Site Public Contact
217-545-7929

Springfield Clinic
Springfield 4250542, Illinois 4896861 62702
Contact:
Site Public Contact
800-444-7541

Springfield Memorial Hospital
Springfield 4250542, Illinois 4896861 62781
Contact:
Site Public Contact
217-528-7541
pallante.beth@mhsil.com

Carle Cancer Center
Urbana 4914570, Illinois 4896861 61801
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Illinois CancerCare - Washington
Washington 4915545, Illinois 4896861 61571
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Rush-Copley Healthcare Center
Yorkville 4917298, Illinois 4896861 60560
Contact:
Site Public Contact
630-978-6212
Cancer.Research@rushcopley.com

Northwest Cancer Center - Main Campus
Crown Point 4919451, Indiana 4921868 46307
Contact:
Site Public Contact
219-310-2550

UChicago Medicine Northwest Indiana
Crown Point 4919451, Indiana 4921868 46307
Contact:
Site Public Contact
855-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Northwest Oncology LLC
Dyer 4919820, Indiana 4921868 46311
Contact:
Site Public Contact
219-924-8178

Northwest Cancer Center - Hobart
Hobart 4921476, Indiana 4921868 46342
Contact:
Site Public Contact
219-947-1795

Saint Mary Medical Center
Hobart 4921476, Indiana 4921868 46342
Contact:
Site Public Contact
219-836-6875
CancerResearch@COMHS.org

Saint Catherine Hospital
Indianapolis 4259418, Indiana 4921868 46312
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

The Community Hospital
Munster 4924014, Indiana 4921868 46321
Contact:
Site Public Contact
219-836-3349

Women's Diagnostic Center - Munster
Munster 4924014, Indiana 4921868 46321
Contact:
Site Public Contact
219-934-8869
mnicholson@comhs.org

Northwest Cancer Center - Valparaiso
Valparaiso 4927537, Indiana 4921868 46383
Contact:
Site Public Contact
219-836-6875
CancerResearch@COMHS.org

Mary Greeley Medical Center
Ames 4846834, Iowa 4862182 50010
Contact:
Site Public Contact
515-956-4132

McFarland Clinic - Ames
Ames 4846834, Iowa 4862182 50010
Contact:
Site Public Contact
515-239-4734
ksoder@mcfarlandclinic.com

UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny 4846960, Iowa 4862182 50023
Contact:
Site Public Contact
515-241-3305

University of Iowa Healthcare Cancer Services Quad Cities
Bettendorf 4848489, Iowa 4862182 52722
Contact:
Site Public Contact
563-355-7733
katherine-daprile@uiowa.edu

McFarland Clinic - Boone
Boone 4849051, Iowa 4862182 50036
Contact:
Site Public Contact
515-956-4132

Mercy Hospital
Cedar Rapids 4850751, Iowa 4862182 52403
Contact:
Site Public Contact
319-365-4673

Oncology Associates at Mercy Medical Center
Cedar Rapids 4850751, Iowa 4862182 52403
Contact:
Site Public Contact
319-363-2690

UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive 4852065, Iowa 4862182 50325
Contact:
Site Public Contact
515-241-3305

Heartland Oncology and Hematology LLP
Council Bluffs 4852832, Iowa 4862182 51503
Contact:
Site Public Contact
712-322-4136

Methodist Jennie Edmundson Hospital
Council Bluffs 4852832, Iowa 4862182 51503
Contact:
Site Public Contact
402-354-7939
kathryn.bartz@nmhs.org

Iowa Methodist Medical Center
Des Moines 4853828, Iowa 4862182 50309
Contact:
Site Public Contact
515-241-6727

UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines 4853828, Iowa 4862182 50309
Contact:
Site Public Contact
515-241-3305

UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines 4853828, Iowa 4862182 50314
Contact:
Site Public Contact
515-241-3305

McFarland Clinic - Trinity Cancer Center
Fort Dodge 4857486, Iowa 4862182 50501
Contact:
Site Public Contact
515-956-4132

University of Iowa/Holden Comprehensive Cancer Center
Iowa City 4862034, Iowa 4862182 52242
Contact:
Site Public Contact
800-237-1225

McFarland Clinic - Jefferson
Jefferson 4862482, Iowa 4862182 50129
Contact:
Site Public Contact
515-956-4132

McFarland Clinic - Marshalltown
Marshalltown 4866371, Iowa 4862182 50158
Contact:
Site Public Contact
515-956-4132

UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee 4880981, Iowa 4862182 50263
Contact:
Site Public Contact
515-241-3305

Central Care Cancer Center - Garden City
Garden City 5445439, Kansas 4273857 67846
Contact:
Site Public Contact
913-948-5588
aroland@kccop.org

Central Care Cancer Center - Great Bend
Great Bend 4272340, Kansas 4273857 67530
Contact:
Site Public Contact
913-948-5588
aroland@kccop.org

HaysMed
Hays 4272782, Kansas 4273857 67601
Contact:
Site Public Contact
785-623-5774

Lawrence Memorial Hospital
Lawrence 4274277, Kansas 4273857 66044
Contact:
Site Public Contact
785-505-2800
Stephanie.Norris@LMH.ORG

The University of Kansas Cancer Center - Olathe
Olathe 4276614, Kansas 4273857 66061
Contact:
Site Public Contact
913-588-1569
OlatheCCResearch@kumc.edu

Freeman Physician Group of Pittsburg
Pittsburg 4277241, Kansas 4273857 66762
Contact:
Site Public Contact
BNMathew@freemanhealth.com

Mercy Hospital Pittsburg
Pittsburg 4277241, Kansas 4273857 66762
Contact:
Site Public Contact
888-446-3729

Salina Regional Health Center
Salina 4278890, Kansas 4273857 67401
Contact:
Site Public Contact
785-452-7038
mleepers@srhc.com

University of Kansas Health System Saint Francis Campus
Topeka 4280539, Kansas 4273857 66606
Contact:
Site Public Contact
785-295-8000

The James Graham Brown Cancer Center at University of Louisville
Louisville 4299276, Kentucky 6254925 40202
Contact:
Site Public Contact
502-562-3429

UofL Health Medical Center Northeast
Louisville 4299276, Kentucky 6254925 40245
Contact:
Site Public Contact
502-852-2755
ctoinfo@louisville.edu

University Medical Center New Orleans
New Orleans 4335045, Louisiana 4331987 70112
Contact:
Site Public Contact
504-210-3539
emede1@lsuhsc.edu

Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore 4347778, Maryland 4361885 21287
Contact:
Site Public Contact
410-955-8804
jhcccro@jhmi.edu

Christiana Care - Union Hospital
Elkton 4354234, Maryland 4361885 21921
Contact:
Site Public Contact
410-443-1360
frank.crum@christianacare.org

Boston Medical Center
Boston 4930956, Massachusetts 6254926 02118
Contact:
Site Public Contact
617-638-8265

Dana-Farber Cancer Institute
Boston 4930956, Massachusetts 6254926 02215
Contact:
Site Public Contact
877-442-3324

Dana-Farber Cancer Institute at Boston Medical Center - Brighton
Brighton 4931353, Massachusetts 6254926 02135
Contact:
Site Public Contact
617-789-2903

Dana-Farber Cancer Institute at Foxborough
Foxborough 4937222, Massachusetts 6254926 02035
Contact:
Site Public Contact
877-338-7425

Dana Farber-Merrimack Valley
Methuen 4943828, Massachusetts 6254926 01844
Contact:
Site Public Contact
877-338-7425

Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
Milford 4943958, Massachusetts 6254926 01757
Contact:
Site Public Contact
877-332-4294

Dana-Farber/Brigham and Women's Cancer Center at South Shore
South Weymouth 4951568, Massachusetts 6254926 02190
Contact:
Site Public Contact
781-624-5000

MyMichigan Medical Center Gratiot
Alma 4984049, Michigan 5001836 48801
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

MyMichigan Medical Center Alpena
Alpena 4984075, Michigan 5001836 49707
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor 4984247, Michigan 5001836 48106
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

McLaren Cancer Institute-Bay City
Bay City 4985180, Michigan 5001836 48706
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton 4986994, Michigan 5001836 48114
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Trinity Health Medical Center - Brighton
Brighton 4986994, Michigan 5001836 48114
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton 4987990, Michigan 5001836 48188
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Trinity Health Medical Center - Canton
Canton 4987990, Michigan 5001836 48188
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Chelsea Hospital
Chelsea 4988628, Michigan 5001836 48118
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea 4988628, Michigan 5001836 48118
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Hematology Oncology Consultants-Clarkston
Clarkston 4988997, Michigan 5001836 48346
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

McLaren Cancer Institute-Clarkston
Clarkston 4988997, Michigan 5001836 48346
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Newland Medical Associates-Clarkston
Clarkston 4988997, Michigan 5001836 48346
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Corewell Health Dearborn Hospital
Dearborn 4990510, Michigan 5001836 48124
Contact:
Site Public Contact
248-551-7695

Wayne State University/Karmanos Cancer Institute
Detroit 4990729, Michigan 5001836 48201
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Henry Ford Health Saint John Hospital
Detroit 4990729, Michigan 5001836 48236
Contact:
Site Public Contact
313-343-3166
Kkeenan1@hfhs.org

Henry Ford River District Hospital
East China Township, Michigan 5001836 48054
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

OSF Saint Francis Hospital and Medical Group
Escanaba 4992232, Michigan 5001836 49829
Contact:
Site Public Contact
920-433-8889
WI_research_admin@hshs.org

Weisberg Cancer Treatment Center
Farmington Hills 4992523, Michigan 5001836 48334
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Corewell Health Farmington Hills Hospital
Farmington Hills 4992523, Michigan 5001836 48336
Contact:
Site Public Contact
248-551-7695

Cancer Hematology Centers - Flint
Flint 4992982, Michigan 5001836 48503
Contact:
Site Public Contact
810-762-8038
wstrong@ghci.org

Genesee Hematology Oncology PC
Flint 4992982, Michigan 5001836 48503
Contact:
Site Public Contact
810-762-8038
wstrong@ghci.org

Genesys Hurley Cancer Institute
Flint 4992982, Michigan 5001836 48503
Contact:
Site Public Contact
810-762-8038
wstrong@ghci.org

Hurley Medical Center
Flint 4992982, Michigan 5001836 48503
Contact:
Site Public Contact
810-762-8038
wstrong@ghci.org

McLaren Cancer Institute-Flint
Flint 4992982, Michigan 5001836 48532
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

MyMichigan Medical Center Gladwin
Gladwin 4993985, Michigan 5001836 48624
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

Henry Ford Saint John Hospital - Academic
Grosse Pointe Woods 4994871, Michigan 5001836 48236
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

Henry Ford Saint John Hospital - Breast
Grosse Pointe Woods 4994871, Michigan 5001836 48236
Contact:
Site Public Contact
313-343-3166
karen.forman@ascension.org

Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods 4994871, Michigan 5001836 48236
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

Karmanos Cancer Institute at McLaren Greater Lansing
Lansing 4998830, Michigan 5001836 48910
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

University of Michigan Health - Sparrow Lansing
Lansing 4998830, Michigan 5001836 48912
Contact:
Site Public Contact
517-364-3712
harsha.trivedi@umhsparrow.org

McLaren Cancer Institute-Lapeer Region
Lapeer 4998842, Michigan 5001836 48446
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Trinity Health Saint Mary Mercy Livonia Hospital
Livonia 4999837, Michigan 5001836 48154
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Henry Ford Saint John Hospital - Macomb Medical
Macomb 5000473, Michigan 5001836 48044
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

Henry Ford Warren Hospital - Breast Macomb
Macomb 5000473, Michigan 5001836 48044
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

MyMichigan Medical Center Midland
Midland 5001929, Michigan 5001836 48670
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

McLaren Cancer Institute-Macomb
Mount Clemens 5002656, Michigan 5001836 48043
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

MyMichigan Medical Center Mount Pleasant
Mount Pleasant 5002714, Michigan 5001836 48858
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

McLaren Cancer Institute-Northern Michigan
Petoskey 5005484, Michigan 5001836 49770
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Hope Cancer Center
Pontiac 5006166, Michigan 5001836 48341
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Michigan Healthcare Professionals Pontiac
Pontiac 5006166, Michigan 5001836 48341
Contact:
Site Public Contact
248-858-6215
Emily.Crofts@trinity-health.org

Newland Medical Associates-Pontiac
Pontiac 5006166, Michigan 5001836 48341
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac 5006166, Michigan 5001836 48341
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

McLaren-Port Huron
Port Huron 5006233, Michigan 5001836 48060
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Oakland Colon Rectal Associates
Royal Oak 5007804, Michigan 5001836 48067
Contact:
Site Public Contact
248-551-7695

Cancer Care Associates PC
Royal Oak 5007804, Michigan 5001836 48073
Contact:
Site Public Contact
248-551-7695

Comprehensive Medical Center PLLC
Royal Oak 5007804, Michigan 5001836 48073
Contact:
Site Public Contact
248-551-7695

Corewell Health William Beaumont University Hospital
Royal Oak 5007804, Michigan 5001836 48073
Contact:
Site Public Contact
248-551-7695

Hematology Oncology Consultants PC-Royal Oak
Royal Oak 5007804, Michigan 5001836 48073
Contact:
Site Public Contact
248-551-7695

Oakland Medical Group
Royal Oak 5007804, Michigan 5001836 48073
Contact:
Site Public Contact
248-551-7695

MyMichigan Medical Center Saginaw
Saginaw 5007989, Michigan 5001836 48601
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Premier Hematology Oncology Care
Sterling Heights 5011148, Michigan 5001836 48312
Contact:
Site Public Contact
248-551-7695

MyMichigan Medical Center Tawas
Tawas City 5011900, Michigan 5001836 48764
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Michigan Institute of Urology-Town Center
Troy 5012639, Michigan 5001836 48084
Contact:
Site Public Contact
248-551-7695

Corewell Health Beaumont Troy Hospital
Troy 5012639, Michigan 5001836 48085
Contact:
Site Public Contact
248-551-7695

Hematology Oncology Consultants PC-Troy
Troy 5012639, Michigan 5001836 48098
Contact:
Site Public Contact
248-551-7695

Henry Ford Health Warren Hospital
Warren 5014051, Michigan 5001836 48093
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

Henry Ford Madison Heights Hospital - Breast
Warren 5014051, Michigan 5001836 48093
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

Henry Ford Warren Hospital - GLCMS
Warren 5014051, Michigan 5001836 48093
Contact:
Site Public Contact
313-343-3166
kforman1@hfhs.org

Huron Gastroenterology PC
Ypsilanti 5015688, Michigan 5001836 48106
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti 5015688, Michigan 5001836 48197
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Riverwood Healthcare Center
Aitkin 5015978, Minnesota 5037779 56431
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health - Baxter Clinic
Baxter 5017396, Minnesota 5037779 56425
Contact:
Site Public Contact
218-828-2880

Sanford Joe Lueken Cancer Center
Bemidji 5017822, Minnesota 5037779 56601
Contact:
Site Public Contact
218-333-5000
OncologyClinicalTrialsFargo@sanfordhealth.org

Essentia Health Saint Joseph's Medical Center
Brainerd 5019116, Minnesota 5037779 56401
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Minnesota Oncology - Burnsville
Burnsville 5019767, Minnesota 5037779 55337
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Cambridge Medical Center
Cambridge 5020068, Minnesota 5037779 55008
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Mercy Hospital
Coon Rapids 5022025, Minnesota 5037779 55433
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Saint Joseph's Crosslake Clinic
Crosslake 5023482, Minnesota 5037779 56442
Contact:
Site Public Contact
218-692-1010

Essentia Health - Deer River Clinic
Deer River 5024099, Minnesota 5037779 56636
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes 5024237, Minnesota 5037779 56501
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Cancer Center
Duluth 5024719, Minnesota 5037779 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's Medical Center
Duluth 5024719, Minnesota 5037779 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Miller-Dwan Hospital
Duluth 5024719, Minnesota 5037779 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Fairview Southdale Hospital
Edina 5025264, Minnesota 5037779 55435
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Ely Clinic
Ely 5025627, Minnesota 5037779 55731
Contact:
Site Public Contact
218-365-7900

Essentia Health - Fosston
Fosston 5027191, Minnesota 5037779 56542
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Hibbing Clinic
Hibbing 5030005, Minnesota 5037779 55746
Contact:
Site Public Contact
218-786-3308

Essentia Health - International Falls Clinic
International Falls 5031404, Minnesota 5037779 56649
Contact:
Site Public Contact
218-283-9431

Fairview Clinics and Surgery Center Maple Grove
Maple Grove 5036493, Minnesota 5037779 55369
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Minnesota Oncology Hematology PA-Maplewood
Maplewood 5036588, Minnesota 5037779 55109
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Saint John's Hospital - Healtheast
Maplewood 5036588, Minnesota 5037779 55109
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Abbott-Northwestern Hospital
Minneapolis 5037649, Minnesota 5037779 55407
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Hennepin County Medical Center
Minneapolis 5037649, Minnesota 5037779 55415
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Health Partners Inc
Minneapolis 5037649, Minnesota 5037779 55454
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Monticello Cancer Center
Monticello 5038045, Minnesota 5037779 55362
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Moose Lake Clinic
Moose Lake 5038132, Minnesota 5037779 55767
Contact:
Site Public Contact
218-485-4481

New Ulm Medical Center
New Ulm 5039173, Minnesota 5037779 56073
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Park Rapids
Park Rapids 5040822, Minnesota 5037779 56470
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health - Saint Joseph's Pequot Lakes Clinic
Pequot Lakes 5041146, Minnesota 5037779 56472
Contact:
Site Public Contact
218-568-4416

Essentia Health - Saint Joseph's Pine River Clinic
Pine River 5041664, Minnesota 5037779 56474
Contact:
Site Public Contact
218-587-4416

Fairview Northland Medical Center
Princeton 5042360, Minnesota 5037779 55371
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

North Memorial Medical Health Center
Robbinsdale 5043439, Minnesota 5037779 55422
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud 5044407, Minnesota 5037779 56303
Contact:
Site Public Contact
877-229-4907
coborncancercenter@centracare.com

Park Nicollet Clinic - Saint Louis Park
Saint Louis Park 5045021, Minnesota 5037779 55416
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Regions Hospital
Saint Paul 5045360, Minnesota 5037779 55101
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

United Hospital
Saint Paul 5045360, Minnesota 5037779 55102
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health Sandstone
Sandstone 5045908, Minnesota 5037779 55072
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Saint Francis Regional Medical Center
Shakopee 5046997, Minnesota 5037779 55379
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Saint Joseph's Staples Clinic
Staples 5048555, Minnesota 5037779 56479
Contact:
Site Public Contact
218-894-7870

Lakeview Hospital
Stillwater 5048814, Minnesota 5037779 55082
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Sanford Thief River Falls Medical Center
Thief River Falls 5049970, Minnesota 5037779 56701
Contact:
Site Public Contact
605-312-3320

Essentia Health Virginia Clinic
Virginia 5051468, Minnesota 5037779 55792
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Ridgeview Medical Center
Waconia 5051640, Minnesota 5037779 55387
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Rice Memorial Hospital
Willmar 5052916, Minnesota 5037779 56201
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Minnesota Oncology Hematology PA-Woodbury
Woodbury 5053358, Minnesota 5037779 55125
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Sanford Cancer Center Worthington
Worthington 5053460, Minnesota 5037779 56187
Contact:
Site Public Contact
605-312-3320

Fairview Lakes Medical Center
Wyoming 5053526, Minnesota 5037779 55092
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Mercy Oncology and Hematology - Clayton-Clarkson
Ballwin 4375663, Missouri 4398678 63011
Contact:
Site Public Contact
888-446-3729

Central Care Cancer Center - Bolivar
Bolivar 4377835, Missouri 4398678 65613
Contact:
Site Public Contact
913-948-5588
aroland@kccop.org

Cox Cancer Center Branson
Branson 4378219, Missouri 4398678 65616
Contact:
Site Public Contact
417-269-4520

Mercy Cancer Center - Cape Girardeau
Cape Girardeau 4379966, Missouri 4398678 63703
Contact:
Site Public Contact
888-446-3729

Saint Francis Medical Center
Cape Girardeau 4379966, Missouri 4398678 63703
Contact:
Site Public Contact
573-334-2230
sfmc@sfmc.net

Parkland Health Center - Farmington
Farmington 4386289, Missouri 4398678 63640
Contact:
Site Public Contact
314-996-5569

Freeman Health System
Joplin 4392768, Missouri 4398678 64804
Contact:
Site Public Contact
417-347-4030
LJCrockett@freemanhealth.com

Mercy Hospital Joplin
Joplin 4392768, Missouri 4398678 64804
Contact:
Site Public Contact
417-556-3074
esmeralda.carrillo@mercy.net

University Health Truman Medical Center
Kansas City 4393217, Missouri 4398678 64108
Contact:
Site Public Contact
816-404-4375

Lake Regional Hospital
Osage Beach 4402040, Missouri 4398678 65065
Contact:
Site Public Contact
573-302-2768
clinicaltrials@lakeregional.com

Mercy Clinic-Rolla-Cancer and Hematology
Rolla 4406282, Missouri 4398678 65401
Contact:
Site Public Contact
573-458-6379

Phelps Health Delbert Day Cancer Institute
Rolla 4406282, Missouri 4398678 65401
Contact:
Site Public Contact
573-458-7504
research@phelpshealth.org

Heartland Regional Medical Center
Saint Joseph 4407010, Missouri 4398678 64506
Contact:
Site Public Contact
816-271-7937
Trisha.England2@mymlc.com

Sainte Genevieve County Memorial Hospital
Sainte Genevieve 4407294, Missouri 4398678 63670
Contact:
Site Public Contact
314-996-5569

Mercy Hospital Springfield
Springfield 4409896, Missouri 4398678 65804
Contact:
Site Public Contact
417-269-4520

CoxHealth South Hospital
Springfield 4409896, Missouri 4398678 65807
Contact:
Site Public Contact
417-269-4520

Mercy Infusion Center - Chippewa
St Louis 4407066, Missouri 4398678 63109
Contact:
Site Public Contact
888-446-3729

Mercy Hospital South
St Louis 4407066, Missouri 4398678 63128
Contact:
Site Public Contact
314-525-6042
Danielle.Werle@mercy.net

Missouri Baptist Medical Center
St Louis 4407066, Missouri 4398678 63131
Contact:
Site Public Contact
314-996-5569

Mercy Hospital Saint Louis
St Louis 4407066, Missouri 4398678 63141
Contact:
Site Public Contact
314-251-7066

Missouri Baptist Sullivan Hospital
Sullivan 4410669, Missouri 4398678 63080
Contact:
Site Public Contact
314-996-5569

BJC Outpatient Center at Sunset Hills
Sunset Hills 4410836, Missouri 4398678 63127
Contact:
Site Public Contact
314-996-5569

Mercy Hospital Washington
Washington 4413621, Missouri 4398678 63090
Contact:
Site Public Contact
636-390-1600

Community Hospital of Anaconda
Anaconda 5637146, Montana 5667009 59711
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Billings Clinic Cancer Center
Billings 5640350, Montana 5667009 59101
Contact:
Site Public Contact
800-996-2663
research@billingsclinic.org

Saint Vincent Frontier Cancer Center
Billings 5640350, Montana 5667009 59102
Contact:
Site Public Contact
800-648-6274

Bozeman Health Deaconess Hospital
Bozeman 5641727, Montana 5667009 59715
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint James Community Hospital and Cancer Treatment Center
Butte 5642934, Montana 5667009 59701
Contact:
Site Public Contact
406-723-2621

Benefis Sletten Cancer Institute
Great Falls 5655240, Montana 5667009 59405
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Great Falls Clinic
Great Falls 5655240, Montana 5667009 59405
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Hi-Line Sletten Cancer Center
Havre 5656497, Montana 5667009 59501
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Benefis Helena Specialty Center
Helena 5656882, Montana 5667009 59601
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Logan Health Medical Center
Kalispell 5660340, Montana 5667009 59901
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Patrick Hospital - Community Hospital
Missoula 5666639, Montana 5667009 59802
Contact:
Site Public Contact
406-327-3118
amy.hanneman@providence.org

Community Medical Center
Missoula 5666639, Montana 5667009 59804
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Nebraska Medicine-Bellevue
Bellevue 5063805, Nebraska 5073708 68123
Contact:
Site Public Contact
402-559-6941
unmcrsa@unmc.edu

Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
Omaha 5074472, Nebraska 5073708 68114
Contact:
Site Public Contact
402-334-4773

Nebraska Methodist Hospital
Omaha 5074472, Nebraska 5073708 68114
Contact:
Site Public Contact
402-354-5144

Nebraska Medicine-Village Pointe
Omaha 5074472, Nebraska 5073708 68118
Contact:
Site Public Contact
402-559-5600

University of Nebraska Medical Center
Omaha 5074472, Nebraska 5073708 68198
Contact:
Site Public Contact
402-559-6941
unmcrsa@unmc.edu

Carson Tahoe Regional Medical Center
Carson City 5501344, Nevada 5509151 89703
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Cancer and Blood Specialists-Henderson
Henderson 5505411, Nevada 5509151 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Henderson
Henderson 5505411, Nevada 5509151 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada-Horizon Ridge
Henderson 5505411, Nevada 5509151 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

OptumCare Cancer Care at Seven Hills
Henderson 5505411, Nevada 5509151 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson 5505411, Nevada 5509151 89074
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Urology - Green Valley
Henderson 5505411, Nevada 5509151 89074
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Pebble
Henderson 5505411, Nevada 5509151 89074
Contact:
Site Public Contact
research@sncrf.org

Oncology Las Vegas - Henderson
Henderson 5505411, Nevada 5509151 89074
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Urology Specialists of Nevada - Green Valley
Henderson 5505411, Nevada 5509151 89074
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Pecos
Las Vegas 5506956, Nevada 5509151 89074
Contact:
Site Public Contact
research@sncrf.org

OptumCare Cancer Care at Charleston
Las Vegas 5506956, Nevada 5509151 89102
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

University Medical Center of Southern Nevada
Las Vegas 5506956, Nevada 5509151 89102
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Hope Cancer Care of Nevada
Las Vegas 5506956, Nevada 5509151 89103
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Radiation Oncology Centers of Nevada Central
Las Vegas 5506956, Nevada 5509151 89106
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Urology Specialists of Nevada - Central
Las Vegas 5506956, Nevada 5509151 89106
Contact:
Site Public Contact
research@sncrf.org

Sunrise Hospital and Medical Center
Las Vegas 5506956, Nevada 5509151 89109
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Prostate Cancer Center
Las Vegas 5506956, Nevada 5509151 89113
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Sunset
Las Vegas 5506956, Nevada 5509151 89113
Contact:
Site Public Contact
research@sncrf.org

Urology Specialists of Nevada - Southwest
Las Vegas 5506956, Nevada 5509151 89113
Contact:
Site Public Contact
research@sncrf.org

Radiation Oncology Centers of Nevada Southeast
Las Vegas 5506956, Nevada 5509151 89119
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Ann M Wierman MD LTD
Las Vegas 5506956, Nevada 5509151 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas 5506956, Nevada 5509151 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Urology - Cathedral Rock
Las Vegas 5506956, Nevada 5509151 89128
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Smoke Ranch
Las Vegas 5506956, Nevada 5509151 89128
Contact:
Site Public Contact
research@smcrf.org

Oncology Las Vegas - Tenaya
Las Vegas 5506956, Nevada 5509151 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

OptumCare Cancer Care at MountainView
Las Vegas 5506956, Nevada 5509151 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Urology Specialists of Nevada - Northwest
Las Vegas 5506956, Nevada 5509151 89128
Contact:
Site Public Contact
research@sncrf.org

Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas 5506956, Nevada 5509151 89135
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas 5506956, Nevada 5509151 89144
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas 5506956, Nevada 5509151 89144
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Summerlin Hospital Medical Center
Las Vegas 5506956, Nevada 5509151 89144
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada
Las Vegas 5506956, Nevada 5509151 89148
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

OptumCare Cancer Care at Fort Apache
Las Vegas 5506956, Nevada 5509151 89148
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas 5506956, Nevada 5509151 89169
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

University Cancer Center
Las Vegas 5506956, Nevada 5509151 89169
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Hope Cancer Care of Nevada-Pahrump
Pahrump 5509851, Nevada 5509151 89048
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Renown Regional Medical Center
Reno 5511077, Nevada 5509151 89502
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Saint Mary's Regional Medical Center
Reno 5511077, Nevada 5509151 89503
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Radiation Oncology Associates
Reno 5511077, Nevada 5509151 89509
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

The Dana-Farber Cancer Institute at Londonderry
Londonderry 5088905, New Hampshire 5090174 03053
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Jefferson Cherry Hill Hospital
Cherry Hill 4501198, New Jersey 5101760 08002
Contact:
Site Public Contact
215-600-9151
ONCTrialNow@jefferson.edu

Sidney Kimmel Cancer Center Washington Township
Sewell 4504048, New Jersey 5101760 08080
Contact:
Site Public Contact
215-600-9151
ONCTrialNow@jefferson.edu

New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn 5110302, New York 5128638 11215
Contact:
Site Public Contact
718-780-3677
Adg9003@nyp.org

The New York Hospital Medical Center of Queens
Flushing 5117472, New York 5128638 11355
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Glens Falls Hospital
Glens Falls 5118693, New York 5128638 12801
Contact:
Site Public Contact
518-926-6700

Northwell Health Cancer Institute at Huntington
Greenlawn 5119377, New York 5128638 11740
Contact:
Site Public Contact
516-734-8896

Northwell Health/Center for Advanced Medicine
Lake Success 5123853, New York 5128638 11042
Contact:
Site Public Contact
516-734-8896

Northern Westchester Hospital
Mount Kisco 5127744, New York 5128638 10549
Contact:
Site Public Contact
914-666-1366
AMellor@northwell.edu

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York 5128581, New York 5128638 10032
Contact:
Site Public Contact
212-342-5162
cancerclinicaltrials@cumc.columbia.edu

Manhattan Eye Ear and Throat Hospital
New York 5128581, New York 5128638 10065
Contact:
Site Public Contact
212-434-4460

NYP/Weill Cornell Medical Center
New York 5128581, New York 5128638 10065
Contact:
Site Public Contact
212-746-1848

Lenox Hill Hospital
New York 5128581, New York 5128638 10075
Contact:
Site Public Contact
516-734-8896

Queens Cancer Center
Rego Park 5133640, New York 5128638 11374
Contact:
Site Public Contact
718-312-3446

University of Rochester
Rochester 5134086, New York 5128638 14642
Contact:
Site Public Contact
585-275-5830

Phelps Memorial Hospital Center
Sleepy Hollow 5138371, New York 5128638 10591
Contact:
Site Public Contact
914-366-1600

Montefiore Medical Center-Einstein Campus
The Bronx 5110266, New York 5128638 10461
Contact:
Site Public Contact
718-379-6866
eskwak@montefiore.org

Montefiore Medical Center-Weiler Hospital
The Bronx 5110266, New York 5128638 10461
Contact:
Site Public Contact
718-379-6866
eskwak@montefiore.org

Wilmot Cancer Institute at Webster
Webster 5143495, New York 5128638 14580
Contact:
Site Public Contact
WCICTOresearch@urmc.rochester.edu

UNC Lineberger Comprehensive Cancer Center
Chapel Hill 4460162, North Carolina 4482348 27599
Contact:
Site Public Contact
877-668-0683
cancerclinicaltrials@med.unc.edu

Southeastern Medical Oncology Center-Clinton
Clinton 4461101, North Carolina 4482348 28328
Contact:
Site Public Contact
919-587-9084
jfields@cancersmoc.com

Southeastern Medical Oncology Center-Goldsboro
Goldsboro 4468261, North Carolina 4482348 27534
Contact:
Site Public Contact
919-587-9084
jfields@cancersmoc.com

East Carolina University
Greenville 4469160, North Carolina 4482348 27834
Contact:
Site Public Contact
252-744-1015
eubankss@ecu.edu

University of North Carolina-Hillsborough Campus
Hillsborough 4471241, North Carolina 4482348 27278
Contact:
Site Public Contact
877-668-0683
cancerclinicaltrials@med.unc.edu

Southeastern Medical Oncology Center-Jacksonville
Jacksonville 4473083, North Carolina 4482348 28546
Contact:
Site Public Contact
910-587-9084
jfields@cancersmoc.com

FirstHealth of the Carolinas-Moore Regional Hospital
Pinehurst 4485272, North Carolina 4482348 28374
Contact:
Site Public Contact
910-715-3500
jcwilliams@firsthealth.org

Sanford Bismarck Medical Center
Bismarck 5688025, North Dakota 5690763 58501
Contact:
Site Public Contact
701-323-5760
OncologyClinicalTrialsFargo@sanfordhealth.org

Essentia Health Cancer Center-South University Clinic
Fargo 5059163, North Dakota 5690763 58103
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Sanford South University Medical Center
Fargo 5059163, North Dakota 5690763 58103
Contact:
Site Public Contact
701-234-6161

Southpointe-Sanford Medical Center Fargo
Fargo 5059163, North Dakota 5690763 58103
Contact:
Site Public Contact
605-312-3320

Sanford Medical Center Fargo
Fargo 5059163, North Dakota 5690763 58104
Contact:
Site Public Contact
800-437-4010

Sanford Broadway Medical Center
Fargo 5059163, North Dakota 5690763 58122
Contact:
Site Public Contact
701-323-5760
OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford Roger Maris Cancer Center
Fargo 5059163, North Dakota 5690763 58122
Contact:
Site Public Contact
701-234-6161
OncologyClinicalTrialsFargo@sanfordhealth.org

Essentia Health - Jamestown Clinic
Jamestown 5059836, North Dakota 5690763 58401
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Strecker Cancer Center-Belpre
Belpre 4506187, Ohio 5165418 45714
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Miami Valley Hospital South
Centerville 4508204, Ohio 5165418 45459
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Adena Regional Medical Center
Chillicothe 4828890, Ohio 5165418 45601
Contact:
Site Public Contact
877-779-7585
Jeffh@columbusccop.org

Ohio State University Comprehensive Cancer Center
Columbus 4509177, Ohio 5165418 43210
Contact:
Site Public Contact
800-293-5066
Jamesline@osumc.edu

Mount Carmel East Hospital
Columbus 4509177, Ohio 5165418 43213
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

The Mark H Zangmeister Center
Columbus 4509177, Ohio 5165418 43219
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mount Carmel Health Center West
Columbus 4509177, Ohio 5165418 43222
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Miami Valley Hospital
Dayton 4509884, Ohio 5165418 45409
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Premier Blood and Cancer Center
Dayton 4509884, Ohio 5165418 45409
Contact:
Site Public Contact
937-276-8320

Miami Valley Hospital North
Dayton 4509884, Ohio 5165418 45415
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Atrium Medical Center-Middletown Regional Hospital
Franklin 4512203, Ohio 5165418 45005-1066
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Central Ohio Breast and Endocrine Surgery
Gahanna 5155393, Ohio 5165418 43230
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Miami Valley Cancer Care and Infusion
Greenville 5156493, Ohio 5165418 45331
Contact:
Site Public Contact
937-569-7515

Mount Carmel Grove City Hospital
Grove City 4513409, Ohio 5165418 43123
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Zangmeister Center Grove City
Grove City 4513409, Ohio 5165418 43123
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Fairfield Medical Center
Lancaster 4516233, Ohio 5165418 43130
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Saint Rita's Medical Center
Lima 5160783, Ohio 5165418 45801
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Marietta Memorial Hospital
Marietta 4517586, Ohio 5165418 45750
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Memorial Hospital
Marysville 5162077, Ohio 5165418 43040
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Knox Community Hospital
Mount Vernon 5163799, Ohio 5165418 43050
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mount Carmel New Albany Surgical Hospital
New Albany 5164202, Ohio 5165418 43054
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Licking Memorial Hospital
Newark 5164466, Ohio 5165418 43055
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Newark Radiation Oncology
Newark 5164466, Ohio 5165418 43055
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mercy Health - Perrysburg Hospital
Perrysburg 5166516, Ohio 5165418 43551
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Southern Ohio Medical Center
Portsmouth 4521816, Ohio 5165418 45662
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Springfield Regional Cancer Center
Springfield 4525353, Ohio 5165418 45504
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Springfield Regional Medical Center
Springfield 4525353, Ohio 5165418 45504
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mercy Health - Saint Vincent Hospital
Toledo 5174035, Ohio 5165418 43608
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mercy Health - Saint Anne Hospital
Toledo 5174035, Ohio 5165418 43623
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mercy Health Sylvania Radiation Oncology Center
Toledo 5174035, Ohio 5165418 43623
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Upper Valley Medical Center
Troy 5174358, Ohio 5165418 45373
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Saint Ann's Hospital
Westerville 5176472, Ohio 5165418 43081
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center
Wilmington 4528463, Ohio 5165418 45177
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Genesis Healthcare System Cancer Care Center
Zanesville 4528923, Ohio 5165418 43701
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

University of Oklahoma Health Sciences Center
Oklahoma City 4544349, Oklahoma 4544379 73104
Contact:
Site Public Contact
405-271-8777
ou-clinical-trials@ouhsc.edu

Mercy Hospital Oklahoma City
Oklahoma City 4544349, Oklahoma 4544379 73120
Contact:
Site Public Contact
405-752-3402

Saint Alphonsus Cancer Care Center-Baker City
Baker City 5712169, Oregon 5744337 97814
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Charles Health System
Bend 5713587, Oregon 5744337 97701
Contact:
Site Public Contact
541-706-2909
nosall@stcharleshealthcare.org

Clackamas Radiation Oncology Center
Clackamas 5719308, Oregon 5744337 97015
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Bay Area Hospital
Coos Bay 5720495, Oregon 5744337 97420
Contact:
Site Public Contact
541-269-8392
cherie.cox@bayareahospital.org

Providence Hood River Memorial Hospital
Hood River 5731777, Oregon 5744337 97031
Contact:
Site Public Contact
503-215-1979
canrsrchstudies@provdience.org

Providence Newberg Medical Center
Newberg 5742726, Oregon 5744337 97132
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Saint Alphonsus Cancer Care Center-Ontario
Ontario 5744166, Oregon 5744337 97914
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Providence Willamette Falls Medical Center
Oregon City 5744253, Oregon 5744337 97045
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Providence Portland Medical Center
Portland 5746545, Oregon 5744337 97213
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Providence Saint Vincent Medical Center
Portland 5746545, Oregon 5744337 97225
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Saint Charles Health System-Redmond
Redmond 5747882, Oregon 5744337 97756
Contact:
Site Public Contact
541-706-2909

Lehigh Valley Hospital-Cedar Crest
Allentown 5178127, Pennsylvania 6254927 18103
Contact:
Site Public Contact
610-402-9543
Morgan_M.Horton@lvhn.org

Lehigh Valley Hospital - Muhlenberg
Bethlehem 5180225, Pennsylvania 6254927 18017
Contact:
Site Public Contact
610-402-9543
Morgan_M.Horton@lvhn.org

Christiana Care Health System-Concord Health Center
Chadds Ford 4557084, Pennsylvania 6254927 19317
Contact:
Site Public Contact
302-623-4450
lbarone@christianacare.org

Geisinger Medical Center
Danville 5186327, Pennsylvania 6254927 17822
Contact:
Site Public Contact
570-271-5251
HemonCCTrials@geisinger.edu

Geisinger Cancer Center Dickson City
Dickson City 5186924, Pennsylvania 6254927 18519
Contact:
Site Public Contact
877-204-6081
hemoncctrials@geisinger.edu

Pocono Medical Center
East Stroudsburg 5188075, Pennsylvania 6254927 18301
Contact:
Site Public Contact
610-402-9543
Morgan_M.Horton@lvhn.org

Geisinger Medical Center-Cancer Center Hazleton
Hazleton 5193011, Pennsylvania 6254927 18201
Contact:
Site Public Contact
570-459-2901
HemonCCTrials@geisinger.edu

Lehigh Valley Hospital-Hazleton
Hazleton 5193011, Pennsylvania 6254927 18201
Contact:
Site Public Contact
610-402-9543
Morgan_M.Horton@lvhn.org

Geisinger Medical Oncology-Lewisburg
Lewisburg 5197842, Pennsylvania 6254927 17837
Contact:
Site Public Contact
570-374-8555
HemonCCTrials@geisinger.edu

Einstein Medical Center Philadelphia
Philadelphia 4560349, Pennsylvania 6254927 19141
Contact:
Site Public Contact
215-456-3880

Geisinger Cancer Services-Pottsville
Pottsville 5207080, Pennsylvania 6254927 17901
Contact:
Site Public Contact
800-275-6401
HemonCCTrials@geisinger.edu

Community Medical Center
Scranton 5211303, Pennsylvania 6254927 18510
Contact:
Site Public Contact
570-703-4768
HemonCCTrials@geisinger.edu

Reading Hospital
West Reading 5218867, Pennsylvania 6254927 19611
Contact:
Site Public Contact
610-988-9323

Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre 5219488, Pennsylvania 6254927 18711
Contact:
Site Public Contact
570-271-5251
HemonCCTrials@geisinger.edu

Asplundh Cancer Pavilion
Willow Grove 5219619, Pennsylvania 6254927 19090
Contact:
Site Public Contact
215-600-9151
ONCTrialNow@jefferson.edu

Medical University of South Carolina
Charleston 4574324, South Carolina 4597040 29425
Contact:
Site Public Contact
843-792-9321
hcc-clinical-trials@musc.edu

Avera Cancer Institute-Aberdeen
Aberdeen 5225857, South Dakota 5769223 57401
Contact:
Site Public Contact
605-622-8700
oncregulatory@avera.org

Avera Cancer Institute - Mitchell
Mitchell 5229794, South Dakota 5769223 57301
Contact:
Site Public Contact
605-322-3096
OncRegulatory@avera.org

Avera Cancer Institute at Pierre
Pierre 5767918, South Dakota 5769223 57501
Contact:
Site Public Contact
605-322-3095
OncRegulatory@avera.org

Rapid City Regional Hospital
Rapid City 5768233, South Dakota 5769223 57701
Contact:
Site Public Contact
605-755-2370
research@monument.health

Sanford Cancer Center Oncology Clinic
Sioux Falls 5231851, South Dakota 5769223 57104
Contact:
Site Public Contact
605-312-3320
OncologyClinicTrialsSF@sanfordhealth.org

Avera Cancer Institute
Sioux Falls 5231851, South Dakota 5769223 57105
Contact:
Site Public Contact
605-322-3095
OncRegulatory@avera.org

Sanford USD Medical Center - Sioux Falls
Sioux Falls 5231851, South Dakota 5769223 57117-5134
Contact:
Site Public Contact
605-312-3320
OncologyClinicalTrialsSF@SanfordHealth.org

Avera Cancer Institute at Yankton
Yankton 5233053, South Dakota 5769223 57078
Contact:
Site Public Contact
605-322-3095
OncRegulatory@avera.org

Parkland Memorial Hospital
Dallas 4684888, Texas 4736286 75235
Contact:
Site Public Contact
214-590-5582
canceranswerline@UTSouthwestern.edu

UT Southwestern Simmons Cancer Center - RedBird
Dallas 4684888, Texas 4736286 75237
Contact:
Site Public Contact
214-648-7097
canceranswerline@utsouthwestern.edu

UT Southwestern/Simmons Cancer Center-Dallas
Dallas 4684888, Texas 4736286 75390
Contact:
Site Public Contact
214-648-7097
canceranswerline@UTSouthwestern.edu

Tarrant County Hospital District/JPS Health Network
Fort Worth 4691930, Texas 4736286 76104
Contact:
Site Public Contact
817-702-5913
macosta02@jpshealth.org

UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth 4691930, Texas 4736286 76104
Contact:
Site Public Contact
214-648-7097
canceranswerline@UTSouthwestern.edu

UT Southwestern Clinical Center at Richardson/Plano
Richardson 4722625, Texas 4736286 75080
Contact:
Site Public Contact
972-669-7044
Suzanne.cole@utsouthwestern.edu

Farmington Health Center
Farmington 5774662, Utah 5549030 84025
Contact:
Site Public Contact
888-424-2100
cancerinfo@hci.utah.edu

University of Utah Sugarhouse Health Center
Salt Lake City 5780993, Utah 5549030 84106
Contact:
Site Public Contact
888-424-2100
cancerinfo@hci.utah.edu

Huntsman Cancer Institute/University of Utah
Salt Lake City 5780993, Utah 5549030 84112
Contact:
Site Public Contact
888-424-2100
cancerinfo@hci.utah.edu

Central Vermont Medical Center/National Life Cancer Treatment
Berlin Corners 5233780, Vermont 5242283 05602
Contact:
Site Public Contact
802-225-5400

University of Vermont Medical Center
Burlington 5234372, Vermont 5242283 05401
Contact:
Site Public Contact
802-656-4101
rpo@uvm.edu

University of Vermont and State Agricultural College
Burlington 5234372, Vermont 5242283 05405
Contact:
Site Public Contact
802-656-8990
rpo@uvm.edu

University of Virginia Cancer Center
Charlottesville 4752031, Virginia 6254928 22908
Contact:
Site Public Contact
434-243-6303
uvacancertrials@hscmail.mcc.virginia.edu

Inova Schar Cancer Institute
Fairfax 4758023, Virginia 6254928 22031
Contact:
Site Public Contact
703-720-5210
Stephanie.VanBebber@inova.org

Inova Fair Oaks Hospital
Fairfax 4758023, Virginia 6254928 22033
Contact:
Site Public Contact
703-720-5210
Stephanie.VanBebber@inova.org

Inova Fairfax Hospital
Falls Church 4758390, Virginia 6254928 22042
Contact:
Site Public Contact
703-208-6650
Stephanie.VanBebber@inova.org

Centra Alan B Pearson Regional Cancer Center
Lynchburg 4771075, Virginia 6254928 24501
Contact:
Site Public Contact
434-200-1495
Kevin.Patel@centrahealth.com

Virginia Cancer Institute
Richmond 4781708, Virginia 6254928 23229
Contact:
Site Public Contact
804-287-3000
smoore@vacancer.com

VCU Massey Cancer Center at Stony Point
Richmond 4781708, Virginia 6254928 23235
Contact:
Site Public Contact
ctoclinops@vcu.edu

VCU Massey Comprehensive Cancer Center
Richmond 4781708, Virginia 6254928 23298
Contact:
Site Public Contact
804-628-6430
CTOclinops@vcu.edu

VCU Community Memorial Health Center
South Hill 4786619, Virginia 6254928 23970
Contact:
Site Public Contact
nemer.elmouallem@vcuhealth.org

Providence Regional Cancer System-Aberdeen
Aberdeen 5785243, Washington 5815135 98520
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

PeaceHealth Saint Joseph Medical Center
Bellingham 5786899, Washington 5815135 98225
Contact:
Site Public Contact
360-788-8223
achapman1@peacehealth.org

Providence Regional Cancer System-Centralia
Centralia 5789683, Washington 5815135 98531
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Swedish Cancer Institute-Edmonds
Edmonds 5793427, Washington 5815135 98026
Contact:
Site Public Contact
206-215-2343
PCRC-NCORP@Swedish.org

Providence Regional Cancer Partnership
Everett 5793933, Washington 5815135 98201
Contact:
Site Public Contact
425-261-3529
marilyn.birchman@providence.org

Swedish Cancer Institute-Issaquah
Issaquah 5798487, Washington 5815135 98029
Contact:
Site Public Contact
206-215-2343
PCRC-NCORP@Swedish.org

Kadlec Clinic Hematology and Oncology
Kennewick 5799610, Washington 5815135 99336
Contact:
Site Public Contact
509-783-4637
research@kadlecmed.org

Providence Regional Cancer System-Lacey
Lacey 5800112, Washington 5815135 98503
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

PeaceHealth Saint John Medical Center
Longview 5801617, Washington 5815135 98632
Contact:
Site Public Contact
360-514-2016
kmakin-bond@peacehealth.org

Skagit Regional Health Cancer Care Center
Mount Vernon 5804127, Washington 5815135 98274
Contact:
Site Public Contact
360-814-2182
rcccclinicalresearch@skagitvalleyhospital.org

Valley Medical Center
Renton 5808189, Washington 5815135 98055
Contact:
Site Public Contact
425-228-3440
research@valleymed.org

Swedish Medical Center-Ballard Campus
Seattle 5809844, Washington 5815135 98107
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-Cherry Hill
Seattle 5809844, Washington 5815135 98122-5711
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-First Hill
Seattle 5809844, Washington 5815135 98122
Contact:
Site Public Contact
206-215-2343
PCRC-NCORP@Swedish.org

PeaceHealth United General Medical Center
Sedro-Woolley 5809902, Washington 5815135 98284
Contact:
Site Public Contact
360-788-8239
achapman1@peacehealth.org

Cancer Care Northwest - Spokane South
Spokane 5811696, Washington 5815135 99202
Contact:
Site Public Contact
509-228-1680
research@ccnw.net

Cancer Care Northwest-Valley
Spokane 5811696, Washington 5815135 99216
Contact:
Site Public Contact
509-228-1680
research@ccnw.net

Cancer Care Northwest-North Spokane
Spokane 5811696, Washington 5815135 99218
Contact:
Site Public Contact
509-228-1680
research@ccnw.net

PeaceHealth Southwest Medical Center
Vancouver 5814616, Washington 5815135 98664
Contact:
Site Public Contact
360-514-3940
kmakin-bond@peacehealth.org

Providence Saint Mary Regional Cancer Center
Walla Walla 5814916, Washington 5815135 99362
Contact:
Site Public Contact
509-897-5993
Cheryl.Dodd@providence.org

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima 5816605, Washington 5815135 98902
Contact:
Site Public Contact
509-574-3535
Memorial-ClinicalTrials@yvmh.org

West Virginia University Charleston Division
Charleston 4801859, West Virginia 4826850 25304
Contact:
Site Public Contact
304-388-9944

Langlade Hospital and Cancer Center
Antigo 5244010, Wisconsin 5279468 54409
Contact:
Site Public Contact
715-623-9869
Juli.Alford@aspirus.org

Duluth Clinic Ashland
Ashland 5244247, Wisconsin 5279468 54806
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Northwest Wisconsin Cancer Center
Ashland 5244247, Wisconsin 5279468 54806
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Aurora Cancer Care-Southern Lakes VLCC
Burlington 5247214, Wisconsin 5279468 53105
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Clinic-Chippewa Center
Chippewa Falls 5248511, Wisconsin 5279468 54729
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aurora Saint Luke's South Shore
Cudahy 5249871, Wisconsin 5279468 53110
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Medical Center-EC Cancer Center
Eau Claire 5251436, Wisconsin 5279468 54701
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aurora Health Care Germantown Health Center
Germantown 5254218, Wisconsin 5279468 53022
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Cancer Care-Grafton
Grafton 5254739, Wisconsin 5279468 53024
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Saint Vincent Hospital Cancer Center Green Bay
Green Bay 5254962, Wisconsin 5279468 54301
Contact:
Site Public Contact
920-433-8889
WI_research_admin@hshs.org

Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay 5254962, Wisconsin 5279468 54303
Contact:
Site Public Contact
920-433-8889
wi_research_admin@hshs.org

Aurora BayCare Medical Center
Green Bay 5254962, Wisconsin 5279468 54311
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Essentia Health-Hayward Clinic
Hayward 5255882, Wisconsin 5279468 54843
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Tamarack Health Hayward Medical Center
Hayward 5255882, Wisconsin 5279468 54843
Contact:
Site Public Contact
218-568-4416

Aurora Cancer Care-Kenosha South
Kenosha 5258393, Wisconsin 5279468 53142
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Gundersen Lutheran Medical Center
La Crosse 5258957, Wisconsin 5279468 54601
Contact:
Site Public Contact
608-775-2385
cancerctr@gundersenhealth.org

Marshfield Medical Center - Ladysmith
Ladysmith 5259048, Wisconsin 5279468 54848
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aurora Bay Area Medical Group-Marinette
Marinette 5261852, Wisconsin 5279468 54143
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Medical Center-Marshfield
Marshfield 5261969, Wisconsin 5279468 54449
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aspirus Medford Hospital
Medford 5262475, Wisconsin 5279468 54451
Contact:
Site Public Contact
715-847-2353
Beth.Knetter@aspirus.org

Aurora Cancer Care-Milwaukee
Milwaukee 5263045, Wisconsin 5279468 53209
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Saint Luke's Medical Center
Milwaukee 5263045, Wisconsin 5279468 53215
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Sinai Medical Center
Milwaukee 5263045, Wisconsin 5279468 53233
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Medical Center - Minocqua
Minocqua 5263156, Wisconsin 5279468 54548
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

ProHealth D N Greenwald Center
Mukwonago 5263965, Wisconsin 5279468 53149
Contact:
Site Public Contact
research.institute@phci.org

Marshfield Medical Center - Neillsville
Neillsville 5264241, Wisconsin 5279468 54456
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Cancer Center of Western Wisconsin
New Richmond 5264475, Wisconsin 5279468 54017
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

ProHealth Oconomowoc Memorial Hospital
Oconomowoc 5265499, Wisconsin 5279468 53066
Contact:
Site Public Contact
262-928-7878

Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls 5265522, Wisconsin 5279468 54154
Contact:
Site Public Contact
920-433-8889
WI_research_admin@hshs.org

Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh 5265838, Wisconsin 5279468 54904
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Cancer Care-Racine
Racine 5268249, Wisconsin 5279468 53406
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aspirus Cancer Care - James Beck Cancer Center
Rhinelander 5268720, Wisconsin 5279468 54501
Contact:
Site Public Contact
715-847-2353
Beth.Knetter@aspirus.org

Marshfield Medical Center-Rice Lake
Rice Lake 5268798, Wisconsin 5279468 54868
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Saint Vincent Hospital Cancer Center at Sheboygan
Sheboygan 5272893, Wisconsin 5279468 53081
Contact:
Site Public Contact
920-433-8889
wi_research_admin@hshs.org

Sheboygan Physicians Group
Sheboygan 5272893, Wisconsin 5279468 53081
Contact:
Site Public Contact
920-433-8889
wi_research_admin@hshs.org

Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan 5272893, Wisconsin 5279468 53081
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Essentia Health-Spooner Clinic
Spooner 5274034, Wisconsin 5279468 54801
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Aspirus Cancer Care - Stevens Point
Stevens Point 5274644, Wisconsin 5279468 54481
Contact:
Site Public Contact
715-847-2353
Beth.Knetter@aspirus.org

Marshfield Medical Center-River Region at Stevens Point
Stevens Point 5274644, Wisconsin 5279468 54482
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay 5274867, Wisconsin 5279468 54235-1495
Contact:
Site Public Contact
920-433-8889
wi_research_admin@hshs.org

Aurora Medical Center in Summit
Summit, Wisconsin 5279468 53066
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Essentia Health Saint Mary's Hospital - Superior
Superior 5275191, Wisconsin 5279468 54880
Contact:
Site Public Contact
701-364-6272

Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers 5276609, Wisconsin 5279468 54241
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

ProHealth Waukesha Memorial Hospital
Waukesha 5278052, Wisconsin 5279468 53188
Contact:
Site Public Contact
262-928-7632

UW Cancer Center at ProHealth Care
Waukesha 5278052, Wisconsin 5279468 53188
Contact:
Site Public Contact
262-928-5539
Chanda.miller@phci.org

Aspirus Regional Cancer Center
Wausau 5278120, Wisconsin 5279468 54401
Contact:
Site Public Contact
877-405-6866

Marshfield Clinic-Wausau Center
Wausau 5278120, Wisconsin 5279468 54401
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aurora Cancer Care-Milwaukee West
Wauwatosa 5278159, Wisconsin 5279468 53226
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora West Allis Medical Center
West Allis 5278420, Wisconsin 5279468 53227
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Medical Center - Weston
Weston 5278693, Wisconsin 5279468 54476
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids 5279436, Wisconsin 5279468 54494
Contact:
Site Public Contact
715-422-7718

Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids 5279436, Wisconsin 5279468 54494
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Memorial Hospital of Laramie County
Cheyenne 5821086, Wyoming 5843591 82001
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Billings Clinic-Cody
Cody 5821593, Wyoming 5843591 82414
Contact:
Site Public Contact
800-996-2663
research@billingsclinic.org

Cancer Center-Metro Medical Center Bayamon
Bayamón 4562831, Puerto Rico 00959-5060
Contact:
Site Public Contact
787-395-7085

Puerto Rico Hematology Oncology Group
Bayamón 4562831, Puerto Rico 00961
Contact:
Site Public Contact
787-780-2865

Doctors Cancer Center
Manatí 4566137, Puerto Rico 00674
Contact:
Site Public Contact
787-621-4397

San Juan Community Oncology Group
San Juan 4568127, Puerto Rico 00917
Contact:
Site Public Contact
787-274-3387

Centro Comprensivo de Cancer de UPR
San Juan 4568127, Puerto Rico 00927
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

PROncology
San Juan 4568127, Puerto Rico 00927
Contact:
Site Public Contact
787-919-7919
info@PRoncology.com

San Juan City Hospital
San Juan 4568127, Puerto Rico 00936
Contact:
Site Public Contact
787-763-1296

More Details

Status
Recruiting
Sponsor
Alliance for Clinical Trials in Oncology

Study Contact

Aishwarya Vijendran
773-834-9613
aishwaryav@bsd.uchicago.edu

Detailed Description

PRIMARY OBJECTIVE: I. To determine if overall survival (OS) is improved in patients who received mFOLFIRINOX +/- nivolumab in comparison to FOLFOX +/- nivolumab as first-line chemotherapy for metastatic gastroesophageal adenocarcinoma. SECONDARY OBJECTIVES: I. To compare other indices of efficacy, including progression-free survival, objective response rates and duration of response between both treatment arms. II. To evaluate safety and tolerability associated with treatment in each of the treatment arms. III. To evaluate the proportion of patients receiving second line of therapy in both arms. IV. To evaluate tolerability of the treatment in both arms using Patient Reported Outcomes-Common Terminology Criteria for Adverse Events (PRO-CTCAE). EXPLORATORY OBJECTIVES: I. Exploratory correlative markers will also be measured and evaluated within and between arms to better assess mechanisms and prognostic impact of markers on impact. These will include baseline PD-L1 combined positive score (CPS) and cell free deoxyribonucleic acid (cfDNA) before and after treatment. II. To evaluate and assess the feasibility and compliance associated with not centrally collecting perceived attribution of protocol treatment to reported adverse events. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients receive fluorouracil intravenously (IV), leucovorin calcium IV, oxaliplatin IV, and irinotecan IV on study and nivolumab IV as clinically indicated. Patients undergo magnetic resonance imaging (MRI) and a computed tomography (CT) scan throughout the trial. Patients may also undergo blood sample collection on study. ARM II: Patients receive fluorouracil IV, leucovorin calcium IV, and oxaliplatin IV on study and nivolumab IV as clinically indicated. Patients undergo MRI and a CT scan throughout the trial. Patients may also undergo blood sample collection on study.