Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis
Purpose
The goal of this project is to develop and validate a reproducible scorecard for the neurological assessment of patients with leptomeningeal metastases that can be used in clinical trials including such patients, as well as in clinical practice.
Conditions
- Leptomeningeal Metastasis
- Leptomeningeal Disease
- Leptomeningeal Neoplasms
- Leptomeningeal Cancer
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Adult patients (18 years or more), female or male - Histologically confirmed diagnosis of extra-CNS primary solid cancer - Diagnosis of leptomeningeal metastases confirmed or probable per EANO ESMO criteria - Performance status compatible with enrolment into clinical trials - Ability to consent - Signed informed consent form from patient - Participation in a parallel clinical trial is allowed in this non-interventional study
Exclusion Criteria
- Inability to give informed consent - Inability to adhere to recommended follow-up according to the treating physician Vulnerable participants will not be included.
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Recruiting Locations
MD Anderson Cancer Center
Houston, Texas 77030
Houston, Texas 77030
More Details
- Status
- Recruiting
- Sponsor
- University of Zurich