Remote Evaluation of MIND Diet
Purpose
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves thinking ability and memory compared to a healthy control diet in persons with Multiple Sclerosis (MS). The main question it aims to answer is: Does the MIND diet improve cognitive performance relative to a control diet in persons with MS? Participants will: Consume one meal that follows the MIND diet or a control meal every day for 3 months, complete online surveys and cognitive testing before and after, and keep a record of the food they eat during the study.
Conditions
- Multiple Sclerosis
- Cognitive Change
- Nutrition, Healthy
Eligibility
- Eligible Ages
- Between 18 Years and 64 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Individuals aged 18-64 years old 2. Self-reported diagnosis of Multiple sclerosis (MS) 3. 20/20 or corrected vision 4. No other neurodegenerative disease diagnosis 5. Stable disease-modifying therapy (DMT) within 6 months 6. Not Pregnant or lactating 7. No food allergies or intolerances 8. Able to consume study meals 9. Not enrolled in another dietary, exercise, or medication study during the study 10. Access to a computer/laptop with internet
Exclusion Criteria
- Individuals younger than 18 or older than 64 years old 2. No self-reported diagnosis of Multiple sclerosis (MS) 3. Not 20/20 or uncorrected vision 4. Other neurodegenerative disease diagnosis 5. Disease modifying therapy (DMT) less than 6 months 6. Pregnant or lactating 7. Food allergies or intolerances 8. Not able to consume study meals 9. Enrolled in another dietary, exercise, or medication study during the study 10. No access to a computer/laptop with internet
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Supportive Care
- Masking
- Single (Participant)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental MIND Diet |
Participants in the active MIND diet group will be asked to consume one ready-to-eat meal per day from Daily Harvest® meal delivery service. The treatment meals will follow MIND diet guidelines and include leafy green vegetables, nuts, legumes, whole grains, berries, and extra virgin olive oil. |
|
|
Active Comparator Control Diet |
Participants in the control diet group will be asked to consume one ready-to-eat meal per day from Daily Harvest® meal delivery service. The Control group will receive daily meals that are isocaloric with the active/experimental meals but will follow a general diet based on the average American diet and Dietary Guidelines for Americans (i.e., vegetables, fruits, nuts, whole grains, and unsaturated fats). |
|
Recruiting Locations
Urbana, Illinois 61801
Naiman Khan, PhD/RD
More Details
- Status
- Recruiting
- Sponsor
- University of Illinois at Urbana-Champaign
Detailed Description
The purpose of this study is to understand how a healthy diet is related to thinking ability and memory in people with multiple sclerosis (MS). This study is fully remote consisting of meals being delivered to participant homes using Daily Harvest meal delivery service. Participants will be asked to consume a microwaveable study meal or prepackaged smoothie every day for 12 weeks. The study meals and smoothies will follow either a dietary pattern thought to improve brain health (Mediterranean-DASH Intervention for Neurodegenerative Delay; MIND), or a control diet, and will include foods commonly found in grocery stores. Participants will not know which diet they are assigned to (active or control). Participants will also be asked to follow simple dietary guidance on a healthy diet in addition to the meals provided. Participants will complete a series of online forms or surveys. Additionally, participants will complete an online cognitive battery from Cambridge Neuropsychological Test Automated Battery (CANTAB) at the beginning and end of the study.