Assessment of Stroke Volume in Shock Using Echocardiography Versus Bioreactive Impedance

Purpose

This study aims to evaluate the correlation between stroke volume measurements obtained by transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring. The primary objective is to assess the level of agreement between these two modalities in critically ill patients.

Conditions

  • Shock
  • Critical Illness

Eligibility

Eligible Ages
Between 18 Years and 90 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age ≥ 18 years - Clinical diagnosis of shock as determined by the treating ICU physician (e.g., hypotension requiring vasopressors or evidence of end-organ hypoperfusion) - Able to obtain informed consent from the patient or a legally authorized representative - Enrollment within 24 hours of ICU admission

Exclusion Criteria

  • Pregnancy - Known severe aortic valve disease or dynamic left ventricular outflow tract obstruction - Morbid obesity (BMI > 40) that precludes accurate echocardiographic imaging Presence of cardiac arrhythmias (e.g., atrial fibrillation with rapid ventricular response) affecting stroke volume measurements - Implanted cardiac assist devices (e.g., LVAD, pacemaker dependency) - Imminent death or decision for comfort care only

Study Design

Phase
Study Type
Observational [Patient Registry]
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Shock Patients This cohort includes adult patients presenting with clinical signs of shock in the intensive care unit. Each participant will undergo stroke volume measurement using both transthoracic echocardiography and bioreactance-based monitoring (Cheetah NICOM) before and after passive leg raising. No therapeutic intervention will be performed as part of the study.
  • Device: Cheetah NICOM
    Bioreactance-based noninvasive cardiac output monitoring device used to measure stroke volume before and after passive leg raising. Used solely for observational measurement. No therapeutic intervention is performed.

Recruiting Locations

University Medical Center Southern Nevada
Las Vegas, Nevada 89102
Contact:
Mutsumi J Kioka, Medical Doctor
7026712345
mutsumi.kioka@unlv.edu

More Details

Status
Recruiting
Sponsor
University of Nevada, Las Vegas

Study Contact

Mutsumi J Kioka, Medical Doctor
7026712345
mutsumi.kioka@unlv.edu

Detailed Description

In this prospective observational study, patients presenting with clinical signs of shock will be enrolled after obtaining informed consent. Stroke volume (SV) will be measured using both transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring (Cheetah NICOM). SV will be recorded before and after passive leg raising (PLR) to evaluate the correlation between the two methods in terms of absolute values and directional changes (increase or decrease). No therapeutic intervention will be performed as part of the study; all clinical decisions will remain under the discretion of the treating medical team.