Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway
Purpose
The study purpose is to gain a better understanding of the needs of adults aged 65 and older while they are receiving chemotherapy by measuring their resilience and tailor care plans based on their individual needs.
Conditions
- Cancer
- Frail
- Chemotherapy
Eligibility
- Eligible Ages
- Over 65 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
Patients with cancer: - Ability to understand and willingness to sign an IRB-approved informed consent - Age ≥ 65 years at the time of enrollment. - Planned to initiate an outpatient chemotherapy regimen (including myelosuppressive biologic/immune therapies) for cancer treatment (any type or stage), either as an initial therapy or as a new line of therapy, with curative or palliative intent. - eFI pre-frail or frail status (available in EHR; defined as eFI > 0.10) within 30 days before enrollment. - Ability to read and understand the English language Providers: - Treating medical oncologist of at least one patient participant who enrolled on to the study and completed baseline assessment.
Exclusion Criteria
Patients: - Documented physical or psychological comorbidity that would limit participant's ability to understand or comply with study procedures for the entire length of the study per the enrolling investigator. - Chemotherapy planned at a facility outside the Atrium Health system. - Currently receiving chemotherapy (defined as planned to continue an on-going treatment rather than starting a new regimen).
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- N/A
- Intervention Model
- Single Group Assignment
- Primary Purpose
- Supportive Care
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Participants 65 years or older with active cancer diagnosis and planned chemotherapy |
Participants aged 65 or older with an active cancer diagnosis who are planned to receive chemotherapy and are eFI pre-frail or frail. Participants will be provided with results and education regarding baseline assessments and offered referrals for supportive care interventions to decrease chemotherapy toxicity |
|
Recruiting Locations
Charlotte, North Carolina 28204
Winston-Salem, North Carolina 27157
More Details
- Status
- Recruiting
- Sponsor
- Wake Forest University Health Sciences
Detailed Description
This is a prospective single-arm intervention trial of patients aged 65 or older with an active cancer diagnosis who are planned to receive chemotherapy and are eFI (Electronic Health Record (EHR)-based frailty index) pre-frail or frail. Patients will be enrolled before initiation of chemotherapy. Following a baseline assessment, subjects will be provided with results regarding their frailty, will be offered referrals for supportive care interventions and will participate in weekly symptom reporting (electronic survey + phone call from research nurse) for 12 weeks. Follow-up assessments will be completed at 12 weeks and a subset of participants and providers in participating clinics will be contacted to consent and participate in an interview to provide feedback on the intervention including barriers/facilitators.