Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

Purpose

The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).

Conditions

  • Exercise Induced Muscle Damage
  • Delayed Onset Muscle Soreness (DOMS)

Eligibility

Eligible Ages
Between 18 Years and 30 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month - good general health with no injuries or health conditions that would affect physical activity - willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study

Exclusion Criteria

  • known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required - underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases - currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window - report using an NSAID more than twice a week on a regular basis

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Prevention
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Probiotic Group
  • Dietary Supplement: Lactobacillus casei
    Probiohealth is the manufacturer of this strain and they use a stringent quality control program that utilizes a multi point product variability check system.
Placebo Comparator
Placebo Group
  • Other: Placebo Capsule(s)
    The brand name of placebo capsules that will be used in this study is Magic Bullet Placebo Capsules. This placebo is manufactured by Progressive Placebo as stated on the product label.

Recruiting Locations

University of Minnesota
Minneapolis 5037649, Minnesota 5037779 55455
Contact:
Jakob Fischer
507-236-8051
fisc0887@d.umn.edu

More Details

Status
Recruiting
Sponsor
University of Minnesota

Study Contact

Jakob Fischer
507-236-8051
fisc0887@d.umn.edu