Triple EIT (Electrical Impedance Tomography)

Purpose

This study plans to learn more about ways to look at participant's lungs using new machines called Electrical Impedance Tomography (EIT). The EIT does not use harmful radiation like CT or x-ray. It is read through electrodes like using EKG reading heartbeats. The investigators want to compare the results of patients who have chronic respiratory disease to patients without chronic respiratory disease to learn more about lung structure and composition.

Conditions

  • Neonates and Preterm Infants
  • Cardiopulmonary

Eligibility

Eligible Ages
Between 2 Weeks and 25 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • 2 weeks to 25 years of age - evidence of cardiopulmonary disease including, but not limited to: 1. Post-prematurity respiratory disease 2. Congenital diaphragmatic hernia 3. Pulmonary Hypertension 4. Congenital heart disease 5. Respiratory failure 6. Neuromuscular Disease 7. Developmental or congenital lung disease OR matched healthy controls (born at term gestation (>36 weeks gestational age) with no cardiopulmonary disease)

Exclusion Criteria

  • <2 weeks of age - Anything that interferes with lead placement on the chest wall (such as, dermatologic conditions, multiple chest tubes, anatomic abnormality, or large dressings that cannot be moved) - No informed consent - Pregnant or lactating - Pacemaker or other metal intrathoracic surgical implant (causes noise in the data)

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Cardiopulmonary disease Have evidence of cardiopulmonary disease including, but not limited to: - Post-prematurity respiratory disease - Congenital diaphragmatic hernia - Pulmonary hypertension - Congenital heart disease - Respiratory failure - Neuromuscular disease - Developmental or congenital lung disease May be imaged with two machines
  • Device: Electrical impedance tomography (EIT)
    Electrical impedance tomography (EIT) is a noninvasive and non-ionizing imaging technique that describes lung ventilation and perfusion
Control matched healthy controls with no cardiopulmonary disease
  • Device: Electrical impedance tomography (EIT)
    Electrical impedance tomography (EIT) is a noninvasive and non-ionizing imaging technique that describes lung ventilation and perfusion

Recruiting Locations

Children's Hospital Colorado
Aurora 5412347, Colorado 5417618 80045
Contact:
Allison Keck
720-777-0734
allison.keck@childrenscolorado.org

More Details

Status
Recruiting
Sponsor
University of Colorado, Denver

Study Contact

Katelyn Enzer, MD
7207779137
allison.keck@childrenscolorado.org