Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors

Purpose

The goal of this clinical trial is to culturally adapt an educational genetic counseling intervention to increase the uptake in genetic counseling and testing among African Americans at risk for heredity cancers. With the help of community stakeholders and clinical genetic professionals the investigators will: - adapt and refine a culturally relevant online educational genetic counseling program for at-risk African Americans - Test the effects of the educational program - collaborate with community leaders and clinical genetic professionals to translate study findings, develop a road map for dissemination to the community, and identify barriers to prepare for future trials. Participants from Detroit Research on Cancer Survivor group will be offered enrollment. Once consent is obtained, questionnaires will be completed before an online genetic counselling intervention immediately after, and at 3 months

Conditions

  • Female Breast Cancer
  • Prostate Cancer
  • Colorectal Carcinoma

Eligibility

Eligible Ages
Between 20 Years and 79 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Participants enrolled in Detroit Research on Cancer Survivors (Detroit ROCS) - Diagnosis of Primary Breast, prostate, or colorectal cancer on or after 1/1/2013 - have received or currently receiving care at Karmanos Cancer Institute - meet one or more of the National Comprehensive Cancer Network (NCCN) guidelines for cancer genetic testing as described below Female breast 1. personal diagnosis at age ≤50 2. personal history of the triple-negative subtype 3. at least 1 close (first- or second-degree) relative diagnosed with breast cancer at age <50 4. at least 1 close relative diagnosed with ovarian cancer 5. 2+ close relatives diagnosed with breast or prostate cancer 6. age <50 AND another primary breast cancer at any age 7. 2+ primary breast cancers at any age OR Prostate 1. personal history of high-risk or very high-risk prostate cancer 2. personal history of regional or metastatic prostate cancer 3. personal history of less than high-risk prostate cancer with a suggestive family history (i.e., father or brother or multiple relatives with prostate cancer diagnosed at age <60; at least 1 relative with breast, ovarian, or pancreatic cancer; or at least 1 relative with colorectal, ovarian, pancreatic, or kidney cancer) OR Colorectal 1. personal diagnosis at age ≤50 2. at least 1 close relative diagnosed with HNPCC at age <50 3. at least 2 close relatives diagnosed with an HNPCC cancer at any age 4. colorectal and >=1 primary endometrial, ovarian, gastric, pancreatic, or prostate

Exclusion Criteria

  • Previous genetic counseling and/or testing

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Health Services Research
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Online Culturally adapted Genetic Counseling Information
Culturally developed online Genetic counseling information will be provided. Questionnaires will be administered pre and post genetic counseling intervention as well as 3 months post intervention
  • Behavioral: Culturally adapted Online Genetic Counseling and Testing Information
    Testing the effects of the educational intervention designed to increase the uptake of genetic counseling testing among at-risk African American survivors

Recruiting Locations

Karmanos Cancer Institute
Detroit, Michigan 48201
Contact:
Jasminder Phalore, MPH
313-576-9735
phalorej@karmanos.org

More Details

Status
Recruiting
Sponsor
Barbara Ann Karmanos Cancer Institute

Study Contact

Jasminder Phalore, MPH
313-576-9735
phalorej@karmanos.org