Impact of Sleep Restriction on Blood Pressure Reactivity

Purpose

The purpose of the research study is to examine the effects of shortened sleep on blood pressure.

Conditions

  • Sleep
  • Blood Pressure

Eligibility

Eligible Ages
Between 18 Years and 45 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Healthy adult men and women - 18-45 years of age - BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group) - Non-pregnant, non-breastfeeding, and non-nicotine users - Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight - Premenopausal

Exclusion Criteria

  • No acute or chronic conditions - Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function - Self-reported history of irregular sleep - Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Non-Randomized
Intervention Model
Crossover Assignment
Primary Purpose
Basic Science
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Sleep Restriction
You will be asked to shorten your sleep to four hours.
  • Behavioral: Sleep Restriction
    You will be asked to shorten your sleep to four hours.
No Intervention
Normal Sleep
You will be asked to sleep for 7-9 hours.

Recruiting Locations

University of Missouri
Columbia, Missouri 65211
Contact:
Jacqueline Limberg
573-882-2544
limberglab@missouri.edu

More Details

Status
Recruiting
Sponsor
University of Missouri-Columbia

Study Contact

Jacqueline Limberg
1-573-882-2544
limberglab@missouri.edu