Exosome-based Omic Signatures of Disease Activity in Cardiac Sarcoidosis (EXODACS)

Purpose

The purpose of this study is to develop a prospective cohort of patients with and without cardiac sarcoidosis as well as active and inactive disease to develop a prospective biobank from which exosome analysis of peripheral blood will derive unique biomarkers of disease activity in cardiac sarcoidosis.

Conditions

  • Cardiac Sarcoidosis
  • Sarcoidosis of the Heart
  • Sarcoidosis With Myocarditis
  • Sarcoidosis, Cardiac

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Adults ≥18 years. - Patients referred to the Cardiac Sarcoid Clinic with a clinical suspicion or a previously confirmed diagnosis of cardiac sarcoidosis. - Undergoing FDG-PET as part of standard care. - Ability to provide informed consent.

Exclusion Criteria

• Inability to provide informed consent.

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Cardiac Sarcoidosis Patients Patients with a clinical suspicion or a previously confirmed diagnosis of cardiac sarcoidosis.
  • Other: Exosome Analysis
    Blood Samples will undergo exosome profiling using mass spectrometry and/or other discovery-based approaches

Recruiting Locations

Mayo Clinic in Rochester
Rochester, Minnesota 55905
Contact:
Anna Pick
507-255-0630
pick.anna@mayo.edu

More Details

Status
Recruiting
Sponsor
Mayo Clinic

Study Contact

Anna Pick
507-255-0630
pick.anna@mayo.edu