Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function

Purpose

This study will examine the relationship of airways resistance measured by oscillometry with ventilation defects measured by Phase Resolved Functional Lung (PREFUL) MRI in healthy human subjects.

Conditions

  • Breathing
  • Lung Function Decreased
  • MRI Imaging
  • Healthy

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Age 18 years or older - Ability to provide consent - Willingness to perform MRI and breathing test - Must be able to speak and understand English

Exclusion Criteria

  • Pregnant - Unable or willing to provide consent or perform the required maneuvers for testing.

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
All participants
  • Device: Airway Oscillometer
    The termoflo c-100 Airwave Oscillometer System is intended to measure respiratory system impedance using the Forced Oscillation Technique (FOT).
  • Diagnostic Test: Phase Resolved Functional Lung MRI
    The Phase Resolved Functional Lung (PREFUL) MRI technique acquires images of the lung so that measures of ventilatory defect percentage can be calculated.

Recruiting Locations

University of Rochester Medical Center
Rochester, New York 14642
Contact:
Partick Donohue, MD
585-210-9301
patrick_donohue@urmc.rochester.edu

More Details

Status
Recruiting
Sponsor
University of Rochester

Study Contact

Patrick Donohue, MD
585-210-9301
patrick_donohue@urmc.rochester.edu