Ejaculatory-Sparing HoLEP vs Standard HoLEP

Purpose

The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.

Conditions

  • Enlarged Prostate (BPH)
  • Enlarged Prostate With Lower Urinary Tract Symptoms

Eligibility

Eligible Ages
Between 18 Years and 100 Years
Eligible Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Patients who are sexually active with antegrade ejaculation who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms.

Exclusion Criteria

  • Patients with pre-existing retrograde ejaculation - Patients who are not sexually active - Patients with indwelling urinary catheter prior to surgery, neurological disease, or history of prior prostatic/urethral surgery that may impact ejaculation - Patients who lack decisional capacity - Patients unable to read/speak English

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
No Intervention
Standard HoLEP 		HoLEP procedure performed using standard care technique.
Active Comparator
ES-HoLEP 		HoLEP procedure performed using ejaculatory-sparing HoLEP technique.
  • Other: Ejaculatory-sparing (ES-sparing) HoLEP
    The ejaculatory sparing technique involves sparing the distal apex of the prostate in particular the anterior portion of the prostate which will allow for coaptation necessary for antegrade ejaculation.

Recruiting Locations

Northwestern University
Chicago, Illinois 60611

More Details

Status
Recruiting
Sponsor
Northwestern University

Study Contact

Alyssa McDonald, MPH
312-695-8146
alyssa.mcdonald@northwestern.edu

Detailed Description

The primary aim of this study is to assess the efficacy of ejaculatory-sparing HoLEP (ES-HoLEP) in preserving ejaculation while also maintaining good urinary outcomes.