Evaluation of Muscle Oxygen With MRI

Purpose

Demonstration of soft tissue hypoxia on MRI using external compression and muscle contraction.

Condition

  • Muscle Oxygenation

Eligibility

Eligible Ages
Between 20 Years and 64 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Alert and oriented. - Able to lift 10lbs. and hold for 30 seconds - Not claustrophobic. - Intact sensation in right upper extremity.

Exclusion Criteria

  • Latex allergy or allergy to isopropyl alcohol. - Skin injury or decreased sensation on right upper extremity.

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Basic Science
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
MRI 		Participant will undergo a single MRI examination of arm with no contrast.
  • Other: Compression and Contraction
    Standard orthopedic Sarmiento brace/ shell applied to participant's arm. Inside the brace will be a standard blood pressure cuff with a soft foam attached. Pressure will be applied intermittently with blood pressure cuff. Participant will also be asked to lift MRI compatible 10 lb. weight.

Recruiting Locations

Mount Sinai Hess Center
New York, New York 10029
Contact:
Christopher Cannistraci, MA
(212) 824-8466
Christopher.Cannistraci@mssm.org

More Details

Status
Recruiting
Sponsor
Icahn School of Medicine at Mount Sinai

Study Contact

Yudell Edelstein, MD
212-244-8864
yudell.edelstein@mountsinai.org

Detailed Description

Participant will undergo a single MRI examination. Standard orthopedic Sarmiento brace/ shell applied to participant's arm. Inside the brace will be a standard blood pressure cuff with a standard brace soft foam attached; blood pressure cuff will be partially inflated. Participant will also be asked to lift MRI compatible 10 lb. weight. Muscle oxygenation will be actively measured using MRI. No medications are being given, and no invasive devices are being used.