MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients
Purpose
This study being done to learn more about the use of medical Magnetic Resonance Imaging (mMRI) and dedicated dental MRI (ddMRI) as a non-invasive diagnosing tool when evaluating potential oral cancerous and precancerous lesions in Fanconi Anemia patients.
Condition
- Fanconi Anemia
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs - Willing to provide informed consent
Exclusion Criteria
- Patient without diagnosis of FA - Patients with FA who are under the age of 18 - Unable to tolerate any MRI due to claustrophobia - Any contraindication for the MRI - Unable to provide informed consent or comply with the study protocol
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| FA patients with a history of HNSCC | This group will receive both mMRI and ddMRI, with an exam, every 3-4 months for 2 years (up to 16 scan (+exam) visits). |
|
| FA patients with no history of HNSCC | This group will receive two scans each of mMRI and ddMRI, with an exam, one year apart (up to 4 scan (+exam) visits). |
|
Recruiting Locations
University of Minnesota
Minneapolis, Minnesota 55455
Minneapolis, Minnesota 55455
More Details
- Status
- Recruiting
- Sponsor
- University of Minnesota