Enhancing Children's Cognitive Function and Achievement Through Carotenoid Consumption
Purpose
The aim of this study is to test the casual relationship between carotenoid supplementation, cognitive function, and achievement over a school-year. The central hypothesis is that, relative to the waitlist placebo group, children receiving the carotenoid supplement will exhibit greater gains in cognitive function and achievement.
Conditions
- Cognitive Change
- Achievement
- Macular Pigmentation
Eligibility
- Eligible Ages
- Between 8 Years and 10 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Child assent and parent/guardian consent - 8-10 years of age - No lutein supplementation within 6-months prior to enrollment (exception of multivitamins containing less than 1 mg lutein/day) - Absence of learning disability (parent-reported) - Tanner scale score ≤ 2 - 20/20 or corrected vision
Exclusion Criteria
- Non-assent of child or non-consent of guardian - Above/below 8-10 years of age - Lutein supplementation within 6-months prior to enrollment (including multivitamins containing more than 1 mg lutein/day) - Identified learning disability (parent-reported) - Tanner scale score > 2 - Not 20/20 or uncorrected vision
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Intervention Model Description
- Randomized, placebo-controlled, double-blind trial.
- Primary Purpose
- Prevention
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Active Supplement |
The active supplementation group participants will be asked to consume a daily carotenoid supplement for 9 months. |
|
|
Placebo Comparator Placebo Control |
The placebo control group participants will be asked to consume a placebo supplement for 9 months. |
|
Recruiting Locations
University of Illinois Urbana-Champaign
Urbana, Illinois 61801
Urbana, Illinois 61801
More Details
- Status
- Recruiting
- Sponsor
- University of Illinois at Urbana-Champaign
Detailed Description
This clinical trial will be a randomized placebo-controlled double-blind trial to examine the effects of carotenoid supplementation on cognitive control, hippocampal-dependent relational memory, and academic achievement among pre-adolescents over one school year (i.e. 9-months).