Purpose

Creatine supplementation has been shown to increase exercise performance at sea level. The goal of this study is to determine the effects of creatine supplementation on exercise performance at simulated altitude.

Condition

Eligibility

Eligible Ages
Between 18 Years and 40 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • 18-40 years old - BMI 18.5 to 40 kg/m2 - Habitually active (>150 minutes per week of moderate-vigorous physical activity)

Exclusion Criteria

  • Pregnant or trying to become pregnant - Recent use of creatine supplementation - Supplemental allergies

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Intervention Model Description
Randomized study to two arms: 1) creatine supplementation, 2) glucose supplementation
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)
Masking Description
Research staff collecting data will be masked to intervention

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Placebo Supplementation
Participants given Placebo (20 grams of glucose) daily in 5-gram servings (4 capsules), 4 times per day for 2 days.
  • Dietary Supplement: Placebo
    Participants given 40 grams of glucose in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.
Experimental
Creatine Supplementation
Participants given Creatine (20 grams of glucose) daily in 5-gram servings (4 capsules), 4 times per day for 2 days.
  • Dietary Supplement: Creatine
    Participants given 40 grams of creatine in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.

Recruiting Locations

California Polytechnic State University
San Luis Obispo, California 93407
Contact:
Todd Hagobian, PhD
805-756-7511
thagobia@calpoly.edu

More Details

Status
Recruiting
Sponsor
California Polytechnic State University-San Luis Obispo

Study Contact

Todd Hagobian, PhD
8057567511
thagobia@calpoly.edu

Detailed Description

Military personnel often encounter harsh environments such as high altitudes and hypoxic conditions, leading to significant constraints on their exercise capacity and performance. At sea-level creatine supplementation increases exercise performance; however no experimental studies have examined the effect of creatine supplementation at simulated altitude. The overall objective of this study is to investigate the effects of creatine supplementation on exercise performance, via a repeated sprints test (Wingate Test) after a 2-day supplementation period, compared to a placebo group.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.