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Purpose

The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB). The study aims to achieve this by utilizing a dual approach that combines subjective self-reporting of pain intensity using the Numeric Rating Scale (NRS) with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG). By integrating these two methods, the study seeks to explore potential correlations between self-reported pain scores and neural responses recorded through EEG, providing insights into the pain experience of this specific patient population. Ultimately, the goal of the study is to enhance the understanding of pain perception mechanisms in individuals with symptomatic acute pulpitis resistant to IANB and potentially guide the development of more effective and personalized pain management strategies for these patients.

Condition

Eligibility

Eligible Ages
Between 18 Years and 50 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

Adults aged [18-50 years]. Clinically diagnosed with symptomatic acute pulpitis based on dental examination and radiographic findings. Demonstrates resistance to inferior alveolar nerve block (IANB). Willing and able to provide informed consent to participate in the study. Able to communicate effectively in the language used for study procedures.

Exclusion Criteria

Individuals with known neurological or psychiatric disorders affecting pain perception. Pregnant individuals or those breastfeeding at the time of the study. History of severe allergies or adverse reactions to local anesthetics or EEG gel. Presence of significant medical conditions that may contraindicate dental procedures or EEG recordings. Individuals taking medications that could significantly affect pain perception (e.g., strong analgesics, sedatives). Any contraindications for dental procedures or EEG recordings as determined by the study's dental and medical professionals. Inability to understand and follow study instructions.

Study Design

Phase
Study Type
Observational
Observational Model
Case-Only
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
symptomatic acute pulpitis Patients with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB)
  • Diagnostic Test: Brain wave analysis using electroencephalography (EEG).
    Asessment of pain with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG).
  • Diagnostic Test: Numerical rate Scale (NRS)
    Asessment of pain with the subjective numercal rate scale method (NRS

Recruiting Locations

Cleveland Dental Institute
Cleveland, Ohio 44128
Contact:
Ahmed A Hashem, Profesor
440-502-1591
a.hashem@cdiohio.org

More Details

Status
Recruiting
Sponsor
Cleveland Dental Institute

Study Contact

Ahmed I Basyoni
3612290038
a.basyoni@cdiohio.org

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.