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Purpose

NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs LO), and an app-based, self-paced version (MAPs App). Participants will include younger breast cancer survivors (BCS) who were diagnosed with breast cancer at or before age 50 years, have completed their primary cancer treatment (i.e., surgery, radiation, and/or chemotherapy) at least 6 months earlier, and report elevated depressive symptoms.

Conditions

Eligibility

Eligible Ages
Between 18 Years and 50 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • The participant or a legally authorized representative must provide study-specific informed consent prior to pre-entry and, for participants treated in the U.S., authorization permitting release of personal health information. - The participant must have been greater than or equal to 18 or less than or equal to 50 years of age at the time of breast cancer diagnosis. - The participant must have a first-time diagnosis of non-metastatic breast cancer which is Stage 0, I, II, or III. - The participant must have a score of greater than or equal to 5 and less than or equal to 14 on the Patient Health Questionnaire-8 item (PHQ-8). - Participants must have completed all primary breast cancer treatments at least 6 months prior to and no more than 5 years prior to registration. Note: Primary treatments include surgery, radiation therapy, adjuvant chemotherapy, targeted therapies (e.g., PARP (poly-ADP ribose polymerase) inhibitors, CDK4/6 inhibitors, TDM-1, pertuzumab, or immunotherapy). (Participants may still be taking adjuvant therapy with trastuzumab or adjuvant endocrine therapy or completing minor reconstructive surgery.) - Participant must be able to understand, speak, read, and write in English or Spanish. - Participant must be willing to participate in a 6-week program to receive training in mindfulness. - Participant must be able to use a smartphone, tablet, or other digital device. - Sex assigned at birth must be female.

Exclusion Criteria

  • Patient Health Questionnaire-8 item (PHQ-8) score of less than 5 or greater than 14 . - Any history or current evidence of recurrent or metastatic breast cancer. - Current or past history of another cancer. Participants with a history of only non-melanoma skin cancer or in situ cervical cancer without chemotherapy treatment would be eligible. - Currently pregnant or planning to become pregnant in the near future. - Participants who are enrolled in other cancer control or behavioral intervention trials that require frequent assessments or training activities.

Study Design

Phase
Phase 3
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Prevention
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Mindfulness (MAPs) Live Online 		Participants assigned to MAPs Live Online (MAPs LO) will be asked to attend 2-hour group sessions once a week for 6 weeks conducted live online over Zoom. Both English and Spanish language participants will be randomized to Arm 1. Sessions will be conducted on an encrypted internet connection and recorded for quality assurance and intervention fidelity. Participants who do not have a home computer, smartphone, tablet, or internet to access the Zoom sessions will have a tablet and hotspot provided by the UCLA research team. Each session provides structured lessons and guided exercises in mindfulness as well as opportunities for reflection and group discussion. Exercises include breath, body, and sound meditations; eating and walking meditations; managing pain; working with difficult thoughts and emotions; and cultivating loving kindness. Home practice is a key component of MAPs, and participants will be instructed to practice mindfulness techniques daily, beginning with 5 minutes
  • Behavioral: Mindfulness (MAPs) Live Online
    Exercises include breath, body, and sound meditations; eating and walking meditations; managing pain; working with difficult thoughts and emotions; and cultivating loving kindness. Home practice is a key component of MAPs, and participants will be instructed to practice mindfulness techniques daily, beginning with 5 minutes daily and increasing to 20 minutes daily using guided meditations. Attendance in the group sessions and home practice will be tracked to determine "dose" of the intervention received.
Experimental
Mindfulness (MAPs) Digital App 		Participants assigned to this condition will be asked to access the MAPs App on their home computer, smartphone, or study supplied tablet over the 6-week intervention period. This will be provided by the UCLA research team. Only English language speakers will be assigned to Arm 2, as the app is currently available only in English at this time. Participants who do not have a home computer, smartphone, tablet, or internet to access the digital app will be provided with a tablet and hotspot by the UCLA research team. The MAPs App translates the content of the MAPs intervention into an app-based format, with lessons, exercises, and guided discussions from the six 2-hour sessions separated into shorter micro-sessions. The digital program is sequential with new content and exercises building on previous sessions. Lessons and other materials are gradually unlocked as participants progress through the program. Engagement with the MAPs App will be tracked to determine "dose" of the inte
  • Behavioral: Mindfulness (MAPs) Digital App
    The digital program is sequential with new content and exercises building on previous sessions. Lessons and other materials are gradually unlocked as participants progress through the program. Engagement with the MAPs App will be tracked to determine "dose" of the intervention received.
Active Comparator
Meditation Only Control Group 		The participants assigned to this condition will be provided with access to guided audio mindfulness meditations developed by the UCLA MARC (Mindfulness Awareness Research Center) and available on an app. Both English and Spanish speakers will be assigned to Arm 3, and the meditations will be available in both languages. Participants who do not have a home computer, smartphone, tablet, or internet to access the meditations will be provided with a tablet and hotspot by the UCLA research team. Use of the meditations will be tracked to determine "dose" of the intervention received. All three study groups will have access to the UCLA MARC mindfulness meditation app throughout the study duration out to 6 months of follow-up.
  • Behavioral: Meditation Only Control Group
    Use of the meditations will be tracked to determine "dose" of the intervention received.

Recruiting Locations

Mayo Clinic Hospital in Arizona
Phoenix 5308655, Arizona 5551752 85054
Contact:
Site Public Contact
855-776-0015

Mercy Hospital Fort Smith
Fort Smith 4111410, Arkansas 4099753 72903
Contact:
Site Public Contact
800-378-9373

Kaiser Permanente-Deer Valley Medical Center
Antioch 5324200, California 5332921 94531
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

AIS Cancer Center at San Joaquin Community Hospital
Bakersfield 5325738, California 5332921 93301
Contact:
Site Public Contact
661-323-4673

Marshall Cancer Center
Cameron Park 5333282, California 5332921 95682
Contact:
Site Public Contact
530-672-7050
cancerservices@marshallmedical.org

UC Irvine Health Cancer Center-Newport
Costa Mesa 5339840, California 5332921 92627
Contact:
Site Public Contact
877-827-8839

Kaiser Permanente Dublin
Dublin 5344157, California 5332921 94568
Contact:
Site Public Contact
877-642-4691

Kaiser Permanente-Fremont
Fremont 5350734, California 5332921 94538
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Fresno Orchard Plaza
Fresno 5350937, California 5332921 93720
Contact:
Site Public Contact
833-574-2273

Kaiser Permanente-Fresno
Fresno 5350937, California 5332921 93720
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine 5359777, California 5332921 92612
Contact:
Site Public Contact
877-827-8839
ucstudy@uci.edu

Fremont - Rideout Cancer Center
Marysville 5370984, California 5332921 95901
Contact:
Site Public Contact
530-749-4400

Kaiser Permanente- Modesto MOB II
Modesto 5373900, California 5332921 95356
Contact:
Site Public Contact
877-642-4691

Kaiser Permanente-Modesto
Modesto 5373900, California 5332921 95356
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Oakland
Oakland 5378538, California 5332921 94611
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange 5379513, California 5332921 92868
Contact:
Site Public Contact
877-827-8839
ucstudy@uci.edu

Eisenhower Medical Center
Rancho Mirage 5386015, California 5332921 92270
Contact:
Site Public Contact
760-834-3798

Kaiser Permanente- Marshall Medical Offices
Redwood City 5386834, California 5332921 94063
Contact:
Site Public Contact
877-642-4691

Kaiser Permanente-Richmond
Richmond 5387428, California 5332921 94801
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Roseville
Roseville 5388881, California 5332921 95661
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Downtown Commons
Sacramento 5389489, California 5332921 95814
Contact:
Site Public Contact
877-642-4691
kpoct@kp.org

Kaiser Permanente-South Sacramento
Sacramento 5389489, California 5332921 95823
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Salinas Valley Memorial
Salinas 5391295, California 5332921 93901
Contact:
Site Public Contact
831-759-1838
tnielsen2@svmh.com

Kaiser Permanente-San Francisco
San Francisco 5391959, California 5332921 94115
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Santa Teresa-San Jose
San Jose 5392171, California 5332921 95119
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente San Leandro
San Leandro 5392263, California 5332921 94577
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser San Rafael-Gallinas
San Rafael 5392567, California 5332921 94903
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Medical Center - Santa Clara
Santa Clara 5393015, California 5332921 95051
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Santa Rosa
Santa Rosa 5393287, California 5332921 95403
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Providence Medical Foundation - Santa Rosa
Santa Rosa 5393287, California 5332921 95403
Contact:
Site Public Contact
707-521-3830

Kaiser Permanente-South San Francisco
South San Francisco 5397765, California 5332921 94080
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Stockton
Stockton 5399020, California 5332921 95210
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee 5403676, California 5332921 96161
Contact:
Site Public Contact
530-582-6450

Kaiser Permanente Medical Center-Vacaville
Vacaville 5405228, California 5332921 95688
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Vallejo
Vallejo 5405380, California 5332921 94589
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Walnut Creek
Walnut Creek 5406990, California 5332921 94596
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

MedStar Washington Hospital Center
Washington D.C. 4140963, District of Columbia 4138106 20010
Contact:
Site Public Contact
202-877-8839

UF Health Cancer Institute - Gainesville
Gainesville 4156404, Florida 4155751 32610
Contact:
Site Public Contact
352-273-8010
cancer-center@ufl.edu

Mayo Clinic in Florida
Jacksonville 4160021, Florida 4155751 32224-9980
Contact:
Site Public Contact
855-776-0015

Tallahassee Memorial HealthCare
Tallahassee 4174715, Florida 4155751 32308
Contact:
Site Public Contact
850-431-0673

Grady Health System
Atlanta 4180439, Georgia 4197000 30303
Contact:
Site Public Contact
404-778-1868

Emory University Hospital Midtown
Atlanta 4180439, Georgia 4197000 30308
Contact:
Site Public Contact
888-946-7447

Emory University Hospital/Winship Cancer Institute
Atlanta 4180439, Georgia 4197000 30322
Contact:
Site Public Contact
404-778-1868

Emory Saint Joseph's Hospital
Atlanta 4180439, Georgia 4197000 30342
Contact:
Site Public Contact
404-851-7115

Emory Decatur Hospital
Decatur 4191124, Georgia 4197000 30033
Contact:
Site Public Contact
440-778-1868
clinicaltrialsoncology@dekalbmedical.org

Kaiser Permanente Moanalua Medical Center
Honolulu 5856195, Hawaii 5855797 96819
Contact:
Site Public Contact
808-432-5195
shelley.a.clark@kp.org

Rush-Copley Medical Center
Aurora 4883817, Illinois 4896861 60504
Contact:
Site Public Contact
630-978-6212
RCMC_Cancer_Research@rush.edu

Illinois CancerCare-Bloomington
Bloomington 4885164, Illinois 4896861 61704
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Canton
Canton 4831990, Illinois 4896861 61520
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

SIH Cancer Institute
Carterville 4235311, Illinois 4896861 62918
Contact:
Site Public Contact
618-985-3333
clinical.research@sih.net

Illinois CancerCare-Carthage
Carthage 4886716, Illinois 4896861 62321
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Northwestern University
Chicago 4887398, Illinois 4896861 60611
Contact:
Site Public Contact
312-695-1301
cancer@northwestern.edu

Rush MD Anderson Cancer Center
Chicago 4887398, Illinois 4896861 60612
Contact:
Site Public Contact
312-226-2371
Cancer_Studies@rush.edu

Carle at The Riverfront
Danville 4889426, Illinois 4896861 61832
Contact:
Site Public Contact
800-446-5532
Research@Carle.com

Cancer Care Specialists of Illinois - Decatur
Decatur 4236895, Illinois 4896861 62526
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Northwestern Medicine Cancer Center Kishwaukee
DeKalb 4889553, Illinois 4896861 60115
Contact:
Site Public Contact
630-352-5360
Donald.Smith3@nm.org

Illinois CancerCare-Dixon
Dixon 4889959, Illinois 4896861 61021
Contact:
Site Public Contact
815-285-7800

Carle Physician Group-Effingham
Effingham 4237727, Illinois 4896861 62401
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Crossroads Cancer Center
Effingham 4237727, Illinois 4896861 62401
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Illinois CancerCare-Eureka
Eureka 4891310, Illinois 4896861 61530
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Galesburg
Galesburg 4893392, Illinois 4896861 61401
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Northwestern Medicine Cancer Center Delnor
Geneva 4893591, Illinois 4896861 60134
Contact:
Site Public Contact
630-352-5360
Donald.Smith3@nm.org

Northwestern Medicine Glenview Outpatient Center
Glenview 4893886, Illinois 4896861 60026
Contact:
Site Public Contact
312-695-1102

Northwestern Medicine Grayslake Outpatient Center
Grayslake 4894465, Illinois 4896861 60030
Contact:
Site Public Contact
312-695-1102

Illinois CancerCare-Kewanee Clinic
Kewanee 4898433, Illinois 4896861 61443
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Northwestern Medicine Lake Forest Hospital
Lake Forest 4899012, Illinois 4896861 60045
Contact:
Site Public Contact
cancertrials@northwestern.edu

Rush MD Anderson Cancer Center at Rush Lisle
Lisle 4900080, Illinois 4896861 60532
Contact:
Site Public Contact
312-226-2371
Cancer_Studies@rush.edu

Illinois CancerCare-Macomb
Macomb 4900817, Illinois 4896861 61455
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Carle Physician Group-Mattoon/Charleston
Mattoon 4244099, Illinois 4896861 61938
Contact:
Site Public Contact
800-446-5532
Research@carle.com

SSM Health Good Samaritan
Mount Vernon 4245152, Illinois 4896861 62864
Contact:
Site Public Contact
618-899-1894
gayla.hall@ssmhealth.com

Carle Cancer Institute Normal
Normal 4903780, Illinois 4896861 61761
Contact:
Site Public Contact
800-446-5532
Research@Carle.com

Cancer Care Center of O'Fallon
O'Fallon 4245926, Illinois 4896861 62269
Contact:
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com

Northwestern Medicine Oak Brook
Oak Brook 4904277, Illinois 4896861 60523
Contact:
Site Public Contact
nctnprogram_rhlccc@northwestern.edu

Rush MD Anderson Cancer Center at Rush Oak Park
Oak Park 4904381, Illinois 4896861 60304
Contact:
Site Public Contact
312-226-2371
Cancer_Studies@rush.edu

Northwestern Medicine Orland Park
Orland Park 4904937, Illinois 4896861 60462
Contact:
Site Public Contact
nctnprogram_rhlccc@northwestern.edu

Illinois CancerCare-Ottawa Clinic
Ottawa 4905006, Illinois 4896861 61350
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Pekin
Pekin 4905599, Illinois 4896861 61554
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peoria
Peoria 4905687, Illinois 4896861 61615
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peru
Peru 4905770, Illinois 4896861 61354
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Princeton
Princeton 4906818, Illinois 4896861 61356
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Southern Illinois University School of Medicine
Springfield 4250542, Illinois 4896861 62702
Contact:
Site Public Contact
217-545-7929

Springfield Clinic
Springfield 4250542, Illinois 4896861 62702
Contact:
Site Public Contact
800-444-7541

Carle Cancer Center
Urbana 4914570, Illinois 4896861 61801
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Northwestern Medicine Cancer Center Warrenville
Warrenville 4915525, Illinois 4896861 60555
Contact:
Site Public Contact
630-352-5360
Donald.Smith3@nm.org

Illinois CancerCare - Washington
Washington 4915545, Illinois 4896861 61571
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Rush-Copley Healthcare Center
Yorkville 4917298, Illinois 4896861 60560
Contact:
Site Public Contact
630-978-6212
Cancer.Research@rushcopley.com

Goshen Center for Cancer Care
Goshen 4920808, Indiana 4921868 46526
Contact:
Site Public Contact
574-364-2973
cccois@goshenhealth.com

Memorial Hospital of South Bend
South Bend 4926563, Indiana 4921868 46601
Contact:
Site Public Contact
800-284-7370

UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny 4846960, Iowa 4862182 50023
Contact:
Site Public Contact
515-241-3305

University of Iowa Healthcare Cancer Services Quad Cities
Bettendorf 4848489, Iowa 4862182 52722
Contact:
Site Public Contact
563-355-7733
katherine-daprile@uiowa.edu

Saint Anthony Regional Hospital
Carroll 4850478, Iowa 4862182 51401
Contact:
Site Public Contact
515-689-7658
sbenson@iora.org

Oncology Associates at Mercy Medical Center
Cedar Rapids 4850751, Iowa 4862182 52403
Contact:
Site Public Contact
319-363-2690

UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive 4852065, Iowa 4862182 50325
Contact:
Site Public Contact
515-241-3305

Iowa Methodist Medical Center
Des Moines 4853828, Iowa 4862182 50309
Contact:
Site Public Contact
515-241-6727

UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines 4853828, Iowa 4862182 50309
Contact:
Site Public Contact
515-241-3305

Mercy Medical Center - Des Moines
Des Moines 4853828, Iowa 4862182 50314
Contact:
Site Public Contact
515-358-6613
cancerresearch@mercydesmoines.org

UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines 4853828, Iowa 4862182 50314
Contact:
Site Public Contact
515-241-3305

University of Iowa/Holden Comprehensive Cancer Center
Iowa City 4862034, Iowa 4862182 52242
Contact:
Site Public Contact
800-237-1225

UI Healthcare Mission Cancer and Blood - Pella
Pella 4870915, Iowa 4862182 50219
Contact:
Site Public Contact
515-282-2921
trials@missioncancer.com

UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee 4880981, Iowa 4862182 50263
Contact:
Site Public Contact
515-241-3305

Cotton O'Neil Cancer Center / Stormont Vail Health
Topeka 4280539, Kansas 4273857 66606
Contact:
Site Public Contact
785-270-4939

Flaget Memorial Hospital
Bardstown 4283133, Kentucky 6254925 40004
Contact:
Site Public Contact
720-874-1881
ResearchInstituteInquiries@CommonSpirit.org

Saint Joseph Hospital East
Lexington 4297983, Kentucky 6254925 40509
Contact:
Site Public Contact
720-874-1881
ResearchInstituteInquiries@CommonSpirit.org

University Medical Center New Orleans
New Orleans 4335045, Louisiana 4331987 70112
Contact:
Site Public Contact
504-210-3539
emede1@lsuhsc.edu

Maryland Proton Treatment Center
Baltimore 4347778, Maryland 4361885 21201
Contact:
Site Public Contact
410-369-5226
info@mdproton.com

University of Maryland/Greenebaum Cancer Center
Baltimore 4347778, Maryland 4361885 21201
Contact:
Site Public Contact
800-888-8823

Sinai Hospital of Baltimore
Baltimore 4347778, Maryland 4361885 21215
Contact:
Site Public Contact
410-601-9083

MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore 4347778, Maryland 4361885 21237
Contact:
Site Public Contact
443-777-7364

MedStar Good Samaritan Hospital
Baltimore 4347778, Maryland 4361885 21239
Contact:
Site Public Contact
410-261-8151
Barbara.rector@medstar.net

UM Upper Chesapeake Medical Center
Bel Air 4348240, Maryland 4361885 21014
Contact:
Site Public Contact
443-643-3010

MedStar Southern Maryland Hospital Center
Clinton 4351871, Maryland 4361885 20735
Contact:
Site Public Contact
301-877-4673

Central Maryland Radiation Oncology in Howard County
Columbia 4352053, Maryland 4361885 21044
Contact:
Site Public Contact
443-546-1300

University of Maryland Shore Medical Center at Easton
Easton 4353962, Maryland 4361885 21601
Contact:
Site Public Contact
410-822-1000
Christina.weisenborn@umm.edu

UM Baltimore Washington Medical Center/Tate Cancer Center
Glen Burnie 4356188, Maryland 4361885 21061
Contact:
Site Public Contact
410-553-8100

UM Capital Region Medical Center
Largo 4360345, Maryland 4361885 20774
Contact:
Site Public Contact
301-755-4397
Sarah.Larson@umm.edu

UM Saint Joseph Medical Center
Towson 4371582, Maryland 4361885 21204
Contact:
Site Public Contact
410-337-4569
Jeanmarie.downing@umm.edu

William E Kahlert Regional Cancer Center/Sinai Hospital
Westminster 4373238, Maryland 4361885 21157
Contact:
Site Public Contact
410-871-6400

Beverly Hospital
Beverly 4930505, Massachusetts 6254926 01915
Contact:
Site Public Contact
978-922-3000

Lahey Hospital and Medical Center
Burlington 4931737, Massachusetts 6254926 01805
Contact:
Site Public Contact
781-744-3421
lhmc-cancer-clinical-trials@lahey.org

Addison Gilbert Hospital
Gloucester 4937829, Massachusetts 6254926 01930
Contact:
Site Public Contact
978-283-4000

Lowell General Hospital
Lowell 4942618, Massachusetts 6254926 01854
Contact:
Site Public Contact
978-788-7084
ghincks@lowellgeneral.org

Lahey Medical Center-Peabody
Peabody 4946863, Massachusetts 6254926 01960
Contact:
Site Public Contact
781-744-3421
lhmc-cancer-clinical-trials@lahey.org

MyMichigan Medical Center Gratiot
Alma 4984049, Michigan 5001836 48801
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

MyMichigan Medical Center Alpena
Alpena 4984075, Michigan 5001836 49707
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor 4984247, Michigan 5001836 48106
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Henry Ford Cancer Institute-Downriver
Brownstown, Michigan 5001836 48183
Contact:
Site Public Contact
313-916-3721
CTOResearch@hfhs.org

Henry Ford Macomb Hospital-Clinton Township
Clinton Township 4989133, Michigan 5001836 48038
Contact:
Site Public Contact
313-916-3721
CTOResearch@hfhs.org

Henry Ford Medical Center-Fairlane
Dearborn 4990510, Michigan 5001836 48126
Contact:
Site Public Contact
313-916-3721
CTOResearch@hfhs.org

Henry Ford Hospital
Detroit 4990729, Michigan 5001836 48202
Contact:
Site Public Contact
313-916-3721
CTOResearch@hfhs.org

MyMichigan Medical Center Gladwin
Gladwin 4993985, Michigan 5001836 48624
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids 4994358, Michigan 5001836 49503
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Allegiance Health
Jackson 4997384, Michigan 5001836 49201
Contact:
Site Public Contact
313-916-3721
CTOResearch@hfhs.org

University of Michigan Health - Sparrow Lansing
Lansing 4998830, Michigan 5001836 48912
Contact:
Site Public Contact
517-364-3712
harsha.trivedi@umhsparrow.org

MyMichigan Medical Center Midland
Midland 5001929, Michigan 5001836 48670
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

MyMichigan Medical Center Mount Pleasant
Mount Pleasant 5002714, Michigan 5001836 48858
Contact:
Site Public Contact
989-631-2469
CVResearch@mymichigan.org

Henry Ford Medical Center-Columbus
Novi 5004062, Michigan 5001836 48377
Contact:
Site Public Contact
313-916-3721
CTOResearch@hfhs.org

Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac 5006166, Michigan 5001836 48341
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Corewell Health Reed City Hospital
Reed City 5006946, Michigan 5001836 49677
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

MyMichigan Medical Center Saginaw
Saginaw 5007989, Michigan 5001836 48601
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

MyMichigan Medical Center Tawas
Tawas City 5011900, Michigan 5001836 48764
Contact:
Site Public Contact
734-712-7251
MCRCwebsitecontactform@stjoeshealth.org

Munson Medical Center
Traverse City 5012495, Michigan 5001836 49684
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Henry Ford West Bloomfield Hospital
West Bloomfield 7259621, Michigan 5001836 48322
Contact:
Site Public Contact
313-916-3721
CTOResearch@hfhs.org

Henry Ford Wyandotte Hospital
Wyandotte 5015599, Michigan 5001836 48192
Contact:
Site Public Contact
nhay@hfhs.org

Essentia Health Saint Joseph's Medical Center
Brainerd 5019116, Minnesota 5037779 56401
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Cancer Center
Duluth 5024719, Minnesota 5037779 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Mayo Clinic Health Systems-Mankato
Mankato 5036420, Minnesota 5037779 56001
Contact:
Site Public Contact
855-776-0015

Mayo Clinic in Rochester
Rochester 5043473, Minnesota 5037779 55905
Contact:
Site Public Contact
855-776-0015

Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus 4422442, Mississippi 4436296 39705
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Baptist Cancer Center-Grenada
Grenada 4428539, Mississippi 4436296 38901
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Mississippi Baptist Medical Center
Jackson 4431410, Mississippi 4436296 39202
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Baptist Memorial Hospital and Cancer Center-Union County
New Albany 4438121, Mississippi 4436296 38652
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Baptist Memorial Hospital and Cancer Center-Oxford
Oxford 4440076, Mississippi 4436296 38655
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven 4446702, Mississippi 4436296 38671
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Lake Regional Hospital
Osage Beach 4402040, Missouri 4398678 65065
Contact:
Site Public Contact
573-302-2768
clinicaltrials@lakeregional.com

Heartland Regional Medical Center
Saint Joseph 4407010, Missouri 4398678 64506
Contact:
Site Public Contact
816-271-7937
Trisha.England2@mymlc.com

Mercy Hospital Springfield
Springfield 4409896, Missouri 4398678 65804
Contact:
Site Public Contact
417-269-4520

Mercy Hospital South
St Louis 4407066, Missouri 4398678 63128
Contact:
Site Public Contact
314-525-6042
Danielle.Werle@mercy.net

Missouri Baptist Medical Center
St Louis 4407066, Missouri 4398678 63131
Contact:
Site Public Contact
314-996-5569

CHI Health Good Samaritan
Kearney 5071348, Nebraska 5073708 68847
Contact:
Site Public Contact
720-874-1881
ResearchInstituteInquiries@CommonSpirit.org

Summit Medical Group
Berkeley Heights 5095617, New Jersey 5101760 07922
Contact:
Site Public Contact
412-339-5294
Roster@nrgoncology.org

Ocean University Medical Center
Brick 5095947, New Jersey 5101760 08724
Contact:
Site Public Contact
201-880-3669

Hunterdon Medical Center
Flemington 5098124, New Jersey 5101760 08822
Contact:
Site Public Contact
908-237-2330

Summit Health - Florham Park Campus
Florham Park 5098095, New Jersey 5101760 07932
Contact:
Site Public Contact
mmackenzie@summithealth.com

Bayshore Community Hospital
Holmdel 5099193, New Jersey 5101760 07733
Contact:
Site Public Contact
412-339-5294
Roster@nrgoncology.org

Southern Ocean County Medical Center
Manahawkin 4502866, New Jersey 5101760 08050
Contact:
Site Public Contact
609-978-3429

Jersey Shore Medical Center
Neptune City 5101687, New Jersey 5101760 07753
Contact:
Site Public Contact
732-776-4240

The Valley Hospital - Luckow Pavilion
Paramus 5102387, New Jersey 5101760 07652
Contact:
Site Public Contact
201-634-5792
clinicaltrialsresearch@valleyhealth.com

Riverview Medical Center/Booker Cancer Center
Red Bank 5103159, New Jersey 5101760 07701
Contact:
Site Public Contact
732-530-2382

Valley Health System Ridgewood Campus
Ridgewood 5103269, New Jersey 5101760 07450
Contact:
Site Public Contact
201-634-5792
clinicaltrialsresearch@valleyhealth.com

Mount Sinai Queens
Astoria 5107464, New York 5128638 11102
Contact:
Site Public Contact
212-824-7309
CCTO@mssm.edu

Glens Falls Hospital
Glens Falls 5118693, New York 5128638 12801
Contact:
Site Public Contact
518-926-6700

Garnet Health Medical Center
Middletown 5126842, New York 5128638 10940
Contact:
Site Public Contact
845-333-1133
jgerlach@garnethealth.org

Mount Sinai Union Square
New York 5128581, New York 5128638 10003
Contact:
Site Public Contact
212-824-7309
CCTO@mssm.edu

Mount Sinai Chelsea
New York 5128581, New York 5128638 10011
Contact:
Site Public Contact
212-824-7309
CCTO@mssm.edu

Mount Sinai West
New York 5128581, New York 5128638 10019
Contact:
Site Public Contact
212-824-7309
CCTO@mssm.edu

Mount Sinai Hospital
New York 5128581, New York 5128638 10029
Contact:
Site Public Contact
212-824-7309
CCTO@mssm.edu

Cone Health MedCenter Asheboro
Asheboro 4453035, North Carolina 4482348 27205
Contact:
Site Public Contact
336-832-0836
stacey.phelps@conehealth.com

Cone Health Cancer Center at Alamance Regional
Burlington 4458228, North Carolina 4482348 27215
Contact:
Site Public Contact
336-832-0836
stacey.phelps@conehealth.com

Cone Health Cancer Center
Greensboro 4469146, North Carolina 4482348 27403
Contact:
Site Public Contact
336-832-0836
stacey.phelps@conehealth.com

Cone Health Cancer Center at Drawbridge Parkway
Greensboro 4469146, North Carolina 4482348 27410
Contact:
Site Public Contact
336-832-0836
stacey.phelps@conehealth.com

Annie Penn Memorial Hospital
Reidsville 4487682, North Carolina 4482348 27320
Contact:
Site Public Contact
336-832-0836
stacey.phelps@conehealth.com

Essentia Health Cancer Center-South University Clinic
Fargo 5059163, North Dakota 5690763 58103
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Indu and Raj Soin Medical Center
Beavercreek 4506008, Ohio 5165418 45431
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

University of Cincinnati Cancer Center-UC Medical Center
Cincinnati 4508722, Ohio 5165418 45219
Contact:
Site Public Contact
513-584-7698
cancer@uchealth.com

Mount Carmel East Hospital
Columbus 4509177, Ohio 5165418 43213
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Armes Family Cancer Center
Findlay 5153924, Ohio 5165418 45840
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Blanchard Valley Hospital
Findlay 5153924, Ohio 5165418 45840
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Mount Carmel Grove City Hospital
Grove City 4513409, Ohio 5165418 43123
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Kettering Medical Center
Kettering 4515843, Ohio 5165418 45429
Contact:
Site Public Contact
937-528-2900
clinical.trials@daytonncorp.org

Memorial Hospital
Marysville 5162077, Ohio 5165418 43040
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Licking Memorial Hospital
Newark 5164466, Ohio 5165418 43055
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mercy Health - Perrysburg Hospital
Perrysburg 5166516, Ohio 5165418 43551
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

Mercy Health - Saint Anne Hospital
Toledo 5174035, Ohio 5165418 43623
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

University of Cincinnati Cancer Center-West Chester
West Chester 4520522, Ohio 5165418 45069
Contact:
Site Public Contact
513-584-7698
cancer@uchealth.com

Saint Ann's Hospital
Westerville 5176472, Ohio 5165418 43081
Contact:
Site Public Contact
614-488-2745
Jeffh@columbusccop.org

University of Oklahoma Health Sciences Center
Oklahoma City 4544349, Oklahoma 4544379 73104
Contact:
Site Public Contact
405-271-8777
ou-clinical-trials@ouhsc.edu

Saint Charles Health System
Bend 5713587, Oregon 5744337 97701
Contact:
Site Public Contact
541-706-2909
nosall@stcharleshealthcare.org

Kaiser Permanente Northwest
Portland 5746545, Oregon 5744337 97227
Contact:
Site Public Contact
503-335-2400
information@kpchr.org

Saint Charles Health System-Redmond
Redmond 5747882, Oregon 5744337 97756
Contact:
Site Public Contact
541-706-2909

WellSpan Medical Oncology and Hematology
Chambersburg 4557109, Pennsylvania 6254927 17201
Contact:
Site Public Contact
717-217-6020

Geisinger Medical Center
Danville 5186327, Pennsylvania 6254927 17822
Contact:
Site Public Contact
570-271-5251
HemonCCTrials@geisinger.edu

Geisinger Cancer Center Dickson City
Dickson City 5186924, Pennsylvania 6254927 18519
Contact:
Site Public Contact
877-204-6081
hemoncctrials@geisinger.edu

Ephrata Cancer Center
Ephrata 5188815, Pennsylvania 6254927 17522
Contact:
Site Public Contact
717-721-4840

Adams Cancer Center
Gettysburg 4558183, Pennsylvania 6254927 17325
Contact:
Site Public Contact
877-441-7957

Geisinger Medical Center-Cancer Center Hazleton
Hazleton 5193011, Pennsylvania 6254927 18201
Contact:
Site Public Contact
570-459-2901
HemonCCTrials@geisinger.edu

Penn State Milton S Hershey Medical Center
Hershey 5193342, Pennsylvania 6254927 17033-0850
Contact:
Site Public Contact
717-531-3779
CTO@hmc.psu.edu

Lancaster General Ann B Barshinger Cancer Institute
Lancaster 5197079, Pennsylvania 6254927 17601
Contact:
Site Public Contact
717-544-0511
nctn@pennmedicine.upenn.edu

Sechler Family Cancer Center
Lebanon 5197517, Pennsylvania 6254927 17042
Contact:
Site Public Contact
717-741-8303
doxenberg@wellspan.org

Geisinger Medical Oncology-Lewisburg
Lewisburg 5197842, Pennsylvania 6254927 17837
Contact:
Site Public Contact
570-374-8555
HemonCCTrials@geisinger.edu

Redeemer Health
Meadowbrook 4559584, Pennsylvania 6254927 19046
Contact:
Site Public Contact
215-938-3555

Geisinger Cancer Services-Pottsville
Pottsville 5207080, Pennsylvania 6254927 17901
Contact:
Site Public Contact
800-275-6401
HemonCCTrials@geisinger.edu

Chester County Hospital
West Chester 4562144, Pennsylvania 6254927 19380
Contact:
Site Public Contact
610-431-5044
carolann.hoppes@pennmedicine.upenn.edu

Reading Hospital
West Reading 5218867, Pennsylvania 6254927 19611
Contact:
Site Public Contact
610-988-9323

Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre 5219488, Pennsylvania 6254927 18711
Contact:
Site Public Contact
570-271-5251
HemonCCTrials@geisinger.edu

WellSpan Health-York Cancer Center
York 4562407, Pennsylvania 6254927 17403
Contact:
Site Public Contact
877-441-7957

Women and Infants Hospital
Providence 5224151, Rhode Island 5224323 02905
Contact:
Site Public Contact
401-274-1122

Beaufort Memorial Hospital
Beaufort 4570284, South Carolina 4597040 29902
Contact:
Site Public Contact
843-522-7819
kwade@bmhsc.org

Prisma Health Cancer Institute - Spartanburg
Boiling Springs 4571805, South Carolina 4597040 29316
Contact:
Site Public Contact
864-522-4317
Kim.Williams3@prismahealth.org

Prisma Health Cancer Institute - Easley
Easley 4577263, South Carolina 4597040 29640
Contact:
Site Public Contact
864-522-4317
Kim.Williams3@prismahealth.org

Tidelands Georgetown Memorial Hospital
Georgetown 4579662, South Carolina 4597040 29440
Contact:
Site Public Contact
843-545-5600
broe@tidelandshealth.org

Prisma Health Cancer Institute - Butternut
Greenville 4580543, South Carolina 4597040 29605
Contact:
Site Public Contact
864-522-4317
Kim.Williams3@prismahealth.org

Prisma Health Cancer Institute - Faris
Greenville 4580543, South Carolina 4597040 29605
Contact:
Site Public Contact
864-522-4317
Kim.Williams3@prismahealth.org

Prisma Health Cancer Institute - Eastside
Greenville 4580543, South Carolina 4597040 29615
Contact:
Site Public Contact
864-522-4317
Kim.Williams3@prismahealth.org

Prisma Health Cancer Institute - Greer
Greer 4580599, South Carolina 4597040 29650
Contact:
Site Public Contact
864-522-4317
Kim.Williams3@prismahealth.org

Prisma Health Cancer Institute - Seneca
Seneca 4595346, South Carolina 4597040 29672
Contact:
Site Public Contact
864-522-4317
Kim.Williams3@prismahealth.org

Rapid City Regional Hospital
Rapid City 5768233, South Dakota 5769223 57701
Contact:
Site Public Contact
605-755-2370
research@monument.health

Baptist Memorial Hospital and Cancer Center-Memphis
Memphis 4641239, Tennessee 4662168 38120
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Vanderbilt Breast Center at One Hundred Oaks
Nashville 4644585, Tennessee 4662168 37204
Contact:
Site Public Contact
800-811-8480

The Don and Sybil Harrington Cancer Center
Amarillo 5516233, Texas 4736286 79106
Contact:
Site Public Contact
806-212-1985
Gina.Cravey@bsahs.org

Inova Alexandria Hospital
Alexandria 4744091, Virginia 6254928 22304
Contact:
Site Public Contact
703-776-2580
Stephanie.VanBebber@inova.org

Inova Schar Cancer Institute
Fairfax 4758023, Virginia 6254928 22031
Contact:
Site Public Contact
703-720-5210
Stephanie.VanBebber@inova.org

Inova Fair Oaks Hospital
Fairfax 4758023, Virginia 6254928 22033
Contact:
Site Public Contact
703-720-5210
Stephanie.VanBebber@inova.org

Inova Fairfax Hospital
Falls Church 4758390, Virginia 6254928 22042
Contact:
Site Public Contact
703-208-6650
Stephanie.VanBebber@inova.org

Inova Loudoun Hospital
Leesburg 4769125, Virginia 6254928 20176
Contact:
Site Public Contact
703-858-6000
Keary.janet@inova.org

Bon Secours Memorial Regional Medical Center
Mechanicsville 4772566, Virginia 6254928 23116
Contact:
Site Public Contact
804-893-8978
anne_carmellat@bshsi.org

Bon Secours Saint Francis Medical Center
Midlothian 4772943, Virginia 6254928 23114
Contact:
Site Public Contact
804-893-8978
anne_carmellat@bshsi.org

Bon Secours Richmond Community Hospital
Richmond 4781708, Virginia 6254928 23223
Contact:
Site Public Contact
804-893-8978
anne_carmellat@bshsi.org

Bon Secours Saint Mary's Hospital
Richmond 4781708, Virginia 6254928 23226
Contact:
Site Public Contact
804-893-8978
anne_carmellat@bshsi.org

VCU Massey Cancer Center at Stony Point
Richmond 4781708, Virginia 6254928 23235
Contact:
Site Public Contact
ctoclinops@vcu.edu

VCU Massey Comprehensive Cancer Center
Richmond 4781708, Virginia 6254928 23298
Contact:
Site Public Contact
804-628-6430
CTOclinops@vcu.edu

Carilion Roanoke Memorial Hospital
Roanoke 4782167, Virginia 6254928 24033
Contact:
Site Public Contact
540-981-7377

Langlade Hospital and Cancer Center
Antigo 5244010, Wisconsin 5279468 54409
Contact:
Site Public Contact
715-623-9869
Juli.Alford@aspirus.org

ThedaCare Regional Cancer Center
Appleton 5244080, Wisconsin 5279468 54911
Contact:
Site Public Contact
920-364-3604
ResearchDept@thedacare.org

ThedaCare Cancer Care - Berlin
Berlin 5245497, Wisconsin 5279468 54923
Contact:
Site Public Contact
920-364-3605
ResearchDept@thedacare.org

Mayo Clinic Health System-Eau Claire Clinic
Eau Claire 5251436, Wisconsin 5279468 54701
Contact:
Site Public Contact
855-776-0015

Saint Vincent Hospital Cancer Center Green Bay
Green Bay 5254962, Wisconsin 5279468 54301
Contact:
Site Public Contact
920-433-8889
WI_research_admin@hshs.org

Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay 5254962, Wisconsin 5279468 54303
Contact:
Site Public Contact
920-433-8889
wi_research_admin@hshs.org

Gundersen Lutheran Medical Center
La Crosse 5258957, Wisconsin 5279468 54601
Contact:
Site Public Contact
608-775-2385
cancerctr@gundersenhealth.org

Mayo Clinic Health System-Franciscan Healthcare
La Crosse 5258957, Wisconsin 5279468 54601
Contact:
Site Public Contact
855-776-0015

Aspirus Medford Hospital
Medford 5262475, Wisconsin 5279468 54451
Contact:
Site Public Contact
715-847-2353
Beth.Knetter@aspirus.org

ProHealth D N Greenwald Center
Mukwonago 5263965, Wisconsin 5279468 53149
Contact:
Site Public Contact
research.institute@phci.org

ThedaCare Regional Medical Center - Neenah
Neenah 5264223, Wisconsin 5279468 54956
Contact:
Site Public Contact
920-364-3605
ResearchDept@thedacare.org

ThedaCare Cancer Care - New London
New London 5264455, Wisconsin 5279468 54961
Contact:
Site Public Contact
920-364-3605
ResearchDept@thedacare.org

ProHealth Oconomowoc Memorial Hospital
Oconomowoc 5265499, Wisconsin 5279468 53066
Contact:
Site Public Contact
262-928-7878

Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls 5265522, Wisconsin 5279468 54154
Contact:
Site Public Contact
920-433-8889
WI_research_admin@hshs.org

ThedaCare Cancer Care - Oshkosh
Oshkosh 5265838, Wisconsin 5279468 54904
Contact:
Site Public Contact
920-364-3605
ResearchDept@thedacare.org

Aspirus Cancer Care - James Beck Cancer Center
Rhinelander 5268720, Wisconsin 5279468 54501
Contact:
Site Public Contact
715-847-2353
Beth.Knetter@aspirus.org

ThedaCare Cancer Care - Shawano
Shawano 5272873, Wisconsin 5279468 54166
Contact:
Site Public Contact
920-364-3605
ResearchDept@thedacare.org

Saint Vincent Hospital Cancer Center at Sheboygan
Sheboygan 5272893, Wisconsin 5279468 53081
Contact:
Site Public Contact
920-433-8889
wi_research_admin@hshs.org

Aspirus Cancer Care - Stevens Point
Stevens Point 5274644, Wisconsin 5279468 54481
Contact:
Site Public Contact
715-847-2353
Beth.Knetter@aspirus.org

Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay 5274867, Wisconsin 5279468 54235-1495
Contact:
Site Public Contact
920-433-8889
wi_research_admin@hshs.org

UW Cancer Center at ProHealth Care
Waukesha 5278052, Wisconsin 5279468 53188
Contact:
Site Public Contact
262-928-5539
Chanda.miller@phci.org

ThedaCare Cancer Care - Waupaca
Waupaca 5278083, Wisconsin 5279468 54981
Contact:
Site Public Contact
920-364-3605
ResearchDept@thedacare.org

Aspirus Regional Cancer Center
Wausau 5278120, Wisconsin 5279468 54401
Contact:
Site Public Contact
877-405-6866

Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids 5279436, Wisconsin 5279468 54494
Contact:
Site Public Contact
715-422-7718

Memorial Hospital of Sweetwater County
Rock Springs 5836898, Wyoming 5843591 82901
Contact:
Site Public Contact
307-352-8381
tharris@sweetwatermemorial.com

Centro Comprensivo de Cancer de UPR
San Juan 4568127, Puerto Rico 00927
Contact:
Site Public Contact
412-339-5294
Roster@nrgoncology.org

PROncology
San Juan 4568127, Puerto Rico 00927
Contact:
Site Public Contact
787-919-7919
info@PRoncology.com

More Details

Status
Recruiting
Sponsor
NRG Oncology

Study Contact

Director Regulatory Affairs
412-339-5300
langerj@nrgoncology.org

Detailed Description

The goal of this trial is to determine if a digital mindfulness meditation-based intervention program can improve the mental health and well-being among younger breast cancer survivors with elevated symptoms of depression. Mindfulness meditation programs provided in person have been shown to be helpful for younger breast cancer survivors. This study will compare different digital approaches for mindfulness training to see which is the most effective. This study will also explore mediators and moderators of intervention effects, which is key for efficiently targeting psychological resources in the oncology setting and may be particularly relevant for deciding between digital intervention approaches for individual patients. Research on moderators of in-person mindfulness-based interventions (MBIs) in cancer populations suggests that patients with worse psychological functioning at study entry tend to benefit more from these interventions, with mixed effects for other predictors. It is unclear whether more distressed patients will show similar benefits in digital interventions that lack in-person check-ins and monitoring by instructors. Thus, investigators will assess baseline distress along with key demographic characteristics and social determinants of health (e.g., race, ethnicity, education, rurality) as potential moderators. With respect to mediators, emotion regulation strategies including rumination and self-kindness have been shown to mediate effects of in-person MBIs on stress and depression in cancer populations, consistent with the broader theoretical and empirical literature on mindfulness. Determining whether these factors predict and explain effects of digital MBIs, and whether these effects differ by delivery mode, is necessary for achieving optimal outcomes of these interventions. Further, investigators will collect information on the cost-effectiveness of these programs, which is critical for payors to make coverage decisions, healthcare providers and employers to make adoption decisions, and patients to make participation decisions.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.