Print

Purpose

GZL1 is an independent study conducted under the GZPL master protocol. GZL1 will evaluate the efficacy and safety of orforglipron for treatment of hypertension in participants with obesity or overweight.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • refer to the GZPL master protocol for screening eligibility.

Exclusion Criteria

  • refer to the GZPL master protocol for screening eligibility.

Study Design

Phase
Phase 3
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Double (Participant, Investigator)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Orforglipron 		Participants will receive orforglipron orally.
  • Drug: Orforglipron
    Administered orally
    Other names:
    • LY3502970
Placebo Comparator
Placebo 		Administered placebo.
  • Drug: Placebo
    placebo administered.

Recruiting Locations

Elite Clinical Studies, LLC
Phoenix 5308655, Arizona 5551752 85018

Valley Clinical Trials, Inc.
Covina 5340175, California 5332921 91723

Valley Clinical Trials, Inc.
Northridge 5377985, California 5332921 91325

Chase Medical Research, LLC
Waterbury 4845193, Connecticut 4831725 06708

Excel Medical Clinical Trials
Boca Raton 4148411, Florida 4155751 33434

Care Access - Brandon
Brandon 4148757, Florida 4155751 33510

Northeast Research Institute - Downtown Office
Jacksonville 4160021, Florida 4155751 32204

East-West Medical Research Institute
Honolulu 5856195, Hawaii 5855797 96814

Ascension Saint Agnes Heart Care
Baltimore 4347778, Maryland 4361885 21229

Lucida Clinical Trials
New Bedford 4945121, Massachusetts 6254926 02740

Arcturus Healthcare , PLC, Troy Internal Medicine Research Division
Troy 5012639, Michigan 5001836 48098

StudyMetrix Research
City of Saint Peters 4407237, Missouri 4398678 63303

Excel Clinical Research, LLC
Las Vegas 5506956, Nevada 5509151 89109

Palm Research Center Sunset
Las Vegas 5506956, Nevada 5509151 89148

Rochester Clinical Research, LLC
Rochester 5134086, New York 5128638 14609

Remington-Davis, Inc
Columbus 4509177, Ohio 5165418 43215

PriMED Clinical Research
Dayton 4509884, Ohio 5165418 45429

Advanced Research Institute - Tigard
Tigard 5756758, Oregon 5744337 97223

Care Access - Mauldin
Mauldin 4586523, South Carolina 4597040 29662

Dallas Heart and Vascular Consultants, PA
Duncanville 4687331, Texas 4736286 75137

Texas Institute of Cardiology, PA
McKinney 4710178, Texas 4736286 75071

North Hills Family Medicine/North Hills Medical Research
North Richland Hills 4715292, Texas 4736286 76180

Advanced Research Institute
Ogden 5779206, Utah 5549030 84405

Carient Heart & Vascular - Manassas
Manassas 4771401, Virginia 6254928 20109

Health Research of Hampton Roads, Inc.
Newport News 4776024, Virginia 6254928 23606

National Clinical Research, Inc
Richmond 4781708, Virginia 6254928 23294

Eastside Research Associates
Redmond 5808079, Washington 5815135 98052

Dorado Medical Complex
Dorado 4564133, Puerto Rico 00646

Puerto Rico Medical Research
Ponce 4566880, Puerto Rico 00717

More Details

Status
Recruiting
Sponsor
Eli Lilly and Company

Study Contact

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
1-317-615-4559
LillyTrials@Lilly.com

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.