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Purpose

The purpose of this research is to evaluate a new technique, quantitative digital subtraction angiography (qDSA), to measure blood flow during liver embolization procedures. Liver transarterial embolization is a way of treating liver tumors by blocking blood flow to it. The qDSA technique could help doctors ensure the blood flow to the tumor is decreased by the right amount by calculating blood flow before, during, and after the procedure. Up to 20 participants will be enrolled for 1 study visit and data collection for up to 6 months.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Give voluntary, written informed consent to participate in this study and willing to comply with study-related evaluation and procedure schedule

Exclusion Criteria

  • Pregnancy or breastfeeding - Patients with an acute kidney injury or stage IV or V chronic kidney disease (Cr greater than 2.4 or estimated glomerular filtration rate (eGFR) less than 30), unless anuric and on dialysis without expected return of renal function. - Patients with an iodinated contrast allergy who cannot be adequately premedicated to receive contrast as part of the embolization procedure. - Patients with a physical or psychological condition that would impair study participation. - The patient is judged unsuitable for study participation by the Investigator for any other reason

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Screening
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Participants Undergoing TAE of the Liver
  • Device: qDSA Blood Flow Measurement
    The research intervention is limited to several additional qDSA image acquisitions, which include administration of additional iodinated contrast medium.

Recruiting Locations

UW Hospital and Clinics
Madison, Wisconsin 53792

More Details

Status
Recruiting
Sponsor
University of Wisconsin, Madison

Study Contact

Radiology Coordinators
608-282-8349
Radstudy@uwhealth.org

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.