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Purpose

The purpose of this study is to see how well LY3938577 works and how safe it is compared to degludec in people with type 2 diabetes. Participation in the study will last about 26 weeks.

Condition

Eligibility

Eligible Ages
Between 18 Years and 70 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Have type 2 diabetes - Are receiving ≥20 units of basal insulin per day and ≤55 units/day and ≤1.5 units/kg/day at screening - Have hemoglobin A1c (HbA1c) 7.5% to 10.5% inclusive - Have a body mass index (BMI) of 20 or higher and less than 35 kilograms per square meter (kg/m2)

Exclusion Criteria

  • Have type 1 diabetes

Study Design

Phase
Phase 2
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
LY3938577 		Participants will receive LY3938577 subcutaneously (SC)
  • Drug: LY3938577
    Administered SC
Active Comparator
Degludec 		Participants will receive degludec SC
  • Drug: Degludec
    Administered SC

Recruiting Locations

Tucson Clinical Research Institute
Tucson, Arizona 85712

Encompass Clinical Research
Spring Valley, California 91978
Contact:
619-660-9068

University Clinical Investigators, Inc.
Tustin, California 92780
Contact:
714-734-7944

Tampa Bay Medical Research
Clearwater, Florida 33761
Contact:
727-724-3316

Encore Medical Research
Hollywood, Florida 33024
Contact:
954-400-1725

Clinical Research of Central Florida
Lakeland, Florida 33805
Contact:
863-853-5400

Encore Medical Research - Weston
Weston, Florida 33331
Contact:
954-777-8827

Iowa Diabetes and Endocrinology Research Center
West Des Moines, Iowa 50266
Contact:
515-329-6800

Washington University School of Medicine
St Louis, Missouri 63110
Contact:
314-712-1765

Accellacare - Wilmington
Wilmington, North Carolina 28401
Contact:
910-799-5500

AMR Clinical
Norman, Oklahoma 73069
Contact:
405-701-8999

Tribe Clinical Research, LLC
Greenville, South Carolina 29607
Contact:
864-334-0141

Holston Medical Group
Bristol, Tennessee 37620
Contact:
423-990-2478

Texas Diabetes & Endocrinology, P.A.
Austin, Texas 78749
Contact:
512-334-3505

Velocity Clinical Research, Dallas
Dallas, Texas 75230

Juno Research
Houston, Texas 77040
Contact:
713-779-5494

Southern Endocrinology Associates
Mesquite, Texas 75149
Contact:
214-693-0904

Consano Clinical Research, LLC
Shavano Park, Texas 78231
Contact:
210-545-4900

Texas Valley Clinical Research
Weslaco, Texas 78596
Contact:
956-431-8090

Chrysalis Clinical Research
St. George, Utah 84790
Contact:
435-656-1704

More Details

Status
Recruiting
Sponsor
Eli Lilly and Company

Study Contact

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
317-615-4559
LillyTrials@Lilly.com

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.