WellSpan-THRIVE Cancer QOL Study
Purpose
Cancer affects millions of people worldwide and can significantly impact not only survival, but also day-to-day quality of life. Treatments such as surgery, chemotherapy, and radiation can cause side effects like fatigue, pain, and neuropathy, which may affect physical function, emotional well-being, and social relationships. While many studies have examined factors that influence quality of life; such as age, type and stage of cancer, and treatment-related symptoms; there is still a need for tools that more fully reflect patients' lived experiences. This study aims to develop and implement a patient-centered quality of life (QOL) survey designed specifically for individuals with cancer. By directly involving patients in sharing what matters most to them, the survey seeks to provide a more complete and accurate understanding of how cancer and its treatment affect daily life. The results will help patients, families, and healthcare providers better identify needs, guide supportive care, and improve overall well-being throughout the cancer journey.
Conditions
- Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
- Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative
- Cancer (Solid Tumors)
- Cancer (With or Without Metastasis)
- Cancer - Ovarian
- Cancer Abdomen
- Cancer (Advanced Stage)
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Age 18 years and above - Primary cancer diagnosis (newly diagnosed within the past 6 months) - Able to sign informed consent.
Exclusion Criteria
- Patients with age<18 years, - Patients with primary non-melanoma skin, neurological malignancies (Brain or brain metastases), and primary hematological malignancies. - Patients with severe cognitive impairment, unable to sign informed consent or unable to complete quality of life questionnaire. - Patients with life expectancy of <90 days, in the opinion of treating investigator.
Study Design
- Phase
- Study Type
- Observational [Patient Registry]
- Observational Model
- Cohort
- Time Perspective
- Prospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| Patients Diagnosed with primary cancer in past 6 months | Patients Diagnosed with primary cancer in past 6 months will be divided into Race, ethnicity and gender and will be looked for differences in quality of life based on these subsets. |
Recruiting Locations
Chambersburg 4557109, Pennsylvania 6254927 17201
Ephrata 5188815, Pennsylvania 6254927 17522
Gettysburg 4558183, Pennsylvania 6254927 17325
Lebanon 5197517, Pennsylvania 6254927 17042
York 4562407, Pennsylvania 6254927 17403
More Details
- Status
- Recruiting
- Sponsor
- WellSpan Health
Detailed Description
Cancer is a leading cause of morbidity and mortality worldwide. With more than 10 million deaths in 2020, it is imposing a significant burden on individuals, families, and healthcare systems.(Sung, Ferlay et al. 2021) Cancer treatment often involves a combination of therapies, such as surgery, chemotherapy, and radiation therapy, which can lead to a range of physical and psychological side effects. Side effects such as fatigue, pain, and neuropathy can greatly affect a cancer patient's quality of life, impacting their ability to function, their emotional health, and their social relationships (Llamas-Ramos, Alvarado-Omenat et al. 2023). Research into cancer-related quality of life (QOL) has become increasingly important, as it helps us understand how cancer impacts every part of a patient's life, not just survival (Moschopoulou, Deane et al. 2021). Involving patients in their own care is a powerful way to boost engagement and gain deeper insight into the factors that influence quality of life during the cancer journey. Many studies have looked at what affects quality of life (QOL) in cancer patients. Factors such as age, stage of disease, type of cancer, education, income, and treatment side effects all play a role. For example, older age, advanced cancer, and certain types like lung or pancreatic cancer can lower QOL .(Cella, Tulsky et al. 1993, Dodd, Miaskowski et al. 2001), while treatment side effects such as fatigue, pain, and neuropathy can make it harder for patients to do daily activities and enjoy life (Yennurajalingam, Rodrigues et al. 2018). Research has made important progress in understanding how physical, emotional, and social issues impact well-being, but challenges remain in fully capturing all the factors that influence QOL for people living with cancer. The goal is to bridge this gap by developing and implementing a patient-centered quality of life (QOL) survey tailored specifically for cancer patients and aims to capture a more accurate and comprehensive picture of the factors that affect their quality of life.