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Purpose

The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences? Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses. Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.

Condition

Eligibility

Eligible Ages
Between 18 Years and 80 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Either aged 18-30 years (young adults) or aged 65-80 years (older adults) (self-report) - Fluent in English (self-report) - Right-handed (self-report) - Cognitively healthy (self report verified by score > 24 on Montreal Cognitive Assessment) - Self-reported normal or corrected-to-normal vision

Exclusion Criteria

  • Self-reported neurological disorder (e.g., Alzheimer's or Parkinson's disease) - Self-reported uncontrolled hypertension, diabetes, or thyroid disorder - Having conditions or devices that are unsafe for MRI (assessed via imaging center's MRI safety screening form) - Self-reported difficulty lying still on one's back for 1-2 hours

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Basic Science
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Experimental Arm 		This is a within-subject design with a single experimental arm
  • Behavioral: Memory decision type
    Subjects will be probed to either remember an association they saw directly during the study phase or to make an inference across indirectly associated items.

Recruiting Locations

University of Wisconsin-Milwaukee
Milwaukee, Wisconsin 53211
Contact:
Caitlin Bowman, PhD
414-251-5010
bowman2@uwm.edu

More Details

Status
Recruiting
Sponsor
Caitlin Bowman

Study Contact

Caitlin Bowman, PhD
414-251-5010
bowman2@uwm.edu

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.