Purpose

The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults. The main questions it aims to answer are: - Does low-intensity resistance training in combination with maximal mental effort increase strength more than low intensity resistance training alone? - Does low-intensity resistance training in combination with maximal mental effort improve neuromuscular function more than low intensity resistance training alone? Participants will be randomly assigned to 1 of 3 groups: - Low intensity resistance training - Low intensity resistance training with maximal mental effort - Control Researchers will compare groups to determine differences in changes in strength, neuromuscular function, and body composition.

Conditions

Eligibility

Eligible Ages
Between 65 Years and 85 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Body mass index between 18.5 - 33 kg·m2 - No structured physical activity in past 2 years - Any unstable condition contradicting exercise - Independently walk with or without assistive device - No significant cognitive impairment

Exclusion Criteria

  • Score of 22 or lower on Montreal Cognitive Assessment - Missing more than 3 training sessions (training groups only) - Pacemaker - Unstable angina - Symptomatic heart failure - Uncontrolled arrythmias - Uncontrolled hypertension (greater or equal to 160/90) - Myocardial infarction in the past 6 months - Uncontrolled type 2 diabetes - Type 1 diabetes - Severe or unstable pulmonary conditions, - Currently on supplemental oxygen therapy - Severe hearing loss or visual impairment - Alzheimer's Disease or significant cognitive impairment - Stroke in the past 6 months or ongoing stroke-induced motor impairment - Any neurological (e.g., Parkinson's) condition affecting motor control - Undergoing chemotherapy - Surgery in past 6 months - Musculoskeletal injury in the past 6 months - Terminal illness - Stage 3 or greater chronic kidney disease

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Intervention Model Description
Two intervention groups will perform different types of low intensity resistance training, and a control group will not perform any resistance training.
Primary Purpose
Other
Masking
Single (Participant)
Masking Description
The mental effort aspect of the study will be concealed from subjects, so they will not be aware of any difference between training groups.

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Low Intensity Resistance Training
This group will perform low intensity, whole-body resistance training.
  • Behavioral: Low Intensity Resistance Training with Maximal Mental Effort
    This training intervention will be 8 weeks of low intensity resistance training, including whole-body and isolated muscle exercises, where participants will perform maximal mental effort by imagining maximal muscle contraction during each exercise.
  • Behavioral: Low Intensity Resistance Training
    This training intervention will be 8 weeks of low intensity resistance training, including whole-body and isolated muscle exercises.
Experimental
Low Intensity Resistance Training with Maximal Mental Effort
This group will perform low intensity, whole-body resistance training with maximal mental effort during muscle contraction.
  • Behavioral: Low Intensity Resistance Training with Maximal Mental Effort
    This training intervention will be 8 weeks of low intensity resistance training, including whole-body and isolated muscle exercises, where participants will perform maximal mental effort by imagining maximal muscle contraction during each exercise.
No Intervention
Control
This group will not perform any training and maintain their regular level of physical activity.

Recruiting Locations

Kennesaw State University
Kennesaw, Georgia 30144
Contact:
Garrett Hester
470-578-4267
ghester4@kennesaw.edu

More Details

Status
Recruiting
Sponsor
Kennesaw State University

Study Contact

Garrett Hester Professor of Exercise Science
470-578-4267
ghester4@kennesaw.edu

Detailed Description

Participants in both training groups will perform 8 weeks of low intensity, whole-body resistance training. Participants in the control group will participate in all testing procedures but not perform any training. Participants from all groups will be instructed to otherwise maintain their normal physical activity levels and dietary habits. All training sessions will be supervised by research personnel at a Kennesaw State University fitness center. Participants will complete 2 training sessions per week for 8 weeks. Each training session will last about 45-60 minutes and consist of 5 exercises, including both multi-joint (leg press, chest press, back row) and single-joint (knee extension, bicep curl) exercises. Participants will perform 2 sets of 15 repetitions for each exercise for the first 2 weeks, then volume will be increased by progressing to 3 sets for the remaining 6 weeks. There will be a 60-second rest interval between sets and a similar tempo will be used between groups. Both training groups will perform the same training protocol, but participants in the maximal mental effort group will mentally urge their muscles to contract maximally during each repetition. That is, despite using a low intensity, participants will imagine the feeling of maximal muscle contraction of the primary muscles during each repetition. Several measures of strength, neuromuscular function, physical function, and body composition will be measured before and after the training or control period.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.