mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Purpose
This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Conditions
- Advanced Esophageal Adenocarcinoma
- Advanced Gastric Adenocarcinoma
- Advanced Gastroesophageal Junction Adenocarcinoma
- Clinical Stage III Esophageal Adenocarcinoma AJCC v8
- Clinical Stage III Gastric Cancer AJCC v8
- Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
- Clinical Stage IV Gastric Cancer AJCC v8
- Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
- Metastatic Esophageal Adenocarcinoma
- Metastatic Gastric Adenocarcinoma
- Metastatic Gastroesophageal Junction Adenocarcinoma
- Unresectable Esophageal Adenocarcinoma
- Unresectable Gastric Adenocarcinoma
- Unresectable Gastroesophageal Junction Adenocarcinoma
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Histologic documentation: HER2 negative adenocarcinoma as defined by American Society of Clinical Oncology (ASCO) College of American Pathologists (CAP) guidelines (Bartley et al., Journal of Clinical Oncology [JCO] 2017) with known PD-L1 CPS (Any CPS is allowed, but should be known prior to registration) - Stage: unresectable or metastatic - Tumor site: esophagus, gastroesophageal junction, or stomach - Measurable disease or non-measurable but evaluable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 - No prior treatment for unresectable or metastatic disease - Prior neoadjuvant or adjuvant cytotoxic chemotherapy or adjuvant immunotherapy is allowed as long as it was completed at least 1 year prior to registration - Age >= 18 years - Eastern Cooperative Oncology Group (ECOG) Performance Status 0 or 1 - Absolute neutrophil count (ANC) >= 1,500/mm^3 - Platelet count >= 100,000/mm^3 - Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min - Total bilirubin =< 1.5 x ULN - Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3 x ULN (in patients with liver metastasis: =< 5 x ULN if clearly attributable to liver metastases) - Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial - Patients positive for human immunodeficiency virus (HIV) are eligible only if they meet all of the following: - On effective anti-retroviral therapy - Undetectable HIV viral load by standard clinical assay =< 6 months of registration - Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better - Patients who will receive nivolumab in addition to chemotherapy must not have any contraindications to immune checkpoint inhibitors - Patients must not have active autoimmune disease that has required systemic treatment within 6 months prior to registration. Patients are permitted to receive immunotherapy if they have vitiligo, type I diabetes, residual hypothyroidism due to autoimmune condition only requiring hormone replacement, psoriasis not requiring systemic treatment, or conditions not expected to recur in the absence of an external trigger (precipitating event) - Patients must not have a condition requiring systemic treatment with either corticosteroids (>10mg/day prednisone equivalents) or other immunosuppressive medications within 14 days prior to registration. Inhaled or topical steroids and adrenal replacement doses (=< 10mg/day prednisone equivalent) are permitted - Patients must not have a history of noninfectious pneumonitis requiring steroids - Patients with prior immune mediated adverse events related to immunotherapy that resulted in permanent treatment discontinuation with these agents are ineligible - This study includes the use of the mandatory patient completed measure, PRO-CTCAE. For this study the PRO-CTCAE is available in English, Spanish, Korean, Chinese (Simplified), and Russian, hence patients must be able to speak, understand and read in these languages. Ad-hoc translation of patient-reported measures is not permitted
Exclusion Criteria
- Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects * Therefore, for women of childbearing potential only, a negative serum or urine pregnancy test done =< 7 days prior to registration is required - No known Gilbert's syndrome or known homozygosity for UGAT1A1*28 polymorphism - No baseline grade >= 2 peripheral neuropathy, neurosensory toxicity, or neuromotor toxicity per CTCAE version (v) 5.0 regardless of causality - No medical condition such as uncontrolled infection or uncontrolled diabetes mellitus which, in the opinion of the treating physician, would make this protocol unreasonably hazardous for the patient - No untreated, symptomatic brain metastasis. Patients with treated brain metastases are eligible if the following criteria are met: 1) follow-up brain imaging done at least in 4 weeks after central nervous system (CNS)-directed therapy shows no evidence of progression and 2) the patient no longer requires steroids, or is on a stable steroid dose for more than four weeks - No allogeneic tissue/organ transplant
Study Design
- Phase
- Phase 3
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Treatment
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Arm I (mFOLFIRINOX, nivolumab) |
Patients receive fluorouracil IV, leucovorin calcium IV, oxaliplatin IV, and irinotecan IV on study and nivolumab IV as clinically indicated. Patients undergo MRI and a CT scan throughout the trial. Patients may also undergo blood sample collection on study. |
|
|
Active Comparator Arm II (mFOLFOX, nivolumab) |
Patients receive fluorouracil IV, leucovorin calcium IV, and oxaliplatin IV on study and nivolumab IV as clinically indicated. Patients undergo MRI and a CT scan throughout the trial. Patients may also undergo blood sample collection on study. |
|
Recruiting Locations
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama 35233
Birmingham, Alabama 35233
Anchorage Associates in Radiation Medicine
Anchorage, Alaska 98508
Anchorage, Alaska 98508
Alaska Breast Care and Surgery LLC
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Alaska Oncology and Hematology LLC
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Alaska Women's Cancer Care
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Katmai Oncology Group
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Providence Alaska Medical Center
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Kingman Regional Medical Center
Kingman, Arizona 86401
Kingman, Arizona 86401
Mercy Hospital Fort Smith
Fort Smith, Arkansas 72903
Fort Smith, Arkansas 72903
Contact:
Site Public Contact
800-378-9373
Site Public Contact
800-378-9373
CARTI Cancer Center
Little Rock, Arkansas 72205
Little Rock, Arkansas 72205
Kaiser Permanente-Deer Valley Medical Center
Antioch, California 94531
Antioch, California 94531
PCR Oncology
Arroyo Grande, California 93420
Arroyo Grande, California 93420
Sutter Auburn Faith Hospital
Auburn, California 95602
Auburn, California 95602
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn, California 95603
Auburn, California 95603
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California 94704
Berkeley, California 94704
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California 91505
Burbank, California 91505
Mills-Peninsula Medical Center
Burlingame, California 94010
Burlingame, California 94010
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park, California 95682
Cameron Park, California 95682
Eden Hospital Medical Center
Castro Valley, California 94546
Castro Valley, California 94546
UC Irvine Health Cancer Center-Newport
Costa Mesa, California 92627
Costa Mesa, California 92627
Contact:
Site Public Contact
877-827-8839
Site Public Contact
877-827-8839
Sutter Davis Hospital
Davis, California 95616
Davis, California 95616
Kaiser Permanente Dublin
Dublin, California 94568
Dublin, California 94568
Contact:
Site Public Contact
877-642-4691
Site Public Contact
877-642-4691
Kaiser Permanente-Fremont
Fremont, California 94538
Fremont, California 94538
Palo Alto Medical Foundation-Fremont
Fremont, California 94538
Fremont, California 94538
Fresno Cancer Center
Fresno, California 93720
Fresno, California 93720
Kaiser Permanente Fresno Orchard Plaza
Fresno, California 93720
Fresno, California 93720
Contact:
Site Public Contact
833-574-2273
Site Public Contact
833-574-2273
Kaiser Permanente-Fresno
Fresno, California 93720
Fresno, California 93720
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California 92612
Irvine, California 92612
Keck Medicine of USC Koreatown
Los Angeles, California 90020
Los Angeles, California 90020
Contact:
Site Public Contact
213-388-0908
Site Public Contact
213-388-0908
Los Angeles General Medical Center
Los Angeles, California 90033
Los Angeles, California 90033
USC / Norris Comprehensive Cancer Center
Los Angeles, California 90033
Los Angeles, California 90033
Contact:
Site Public Contact
323-865-0451
Site Public Contact
323-865-0451
Memorial Medical Center
Modesto, California 95355
Modesto, California 95355
Kaiser Permanente- Modesto MOB II
Modesto, California 95356
Modesto, California 95356
Contact:
Site Public Contact
877-642-4691
Site Public Contact
877-642-4691
Kaiser Permanente-Modesto
Modesto, California 95356
Modesto, California 95356
Palo Alto Medical Foundation-Camino Division
Mountain View, California 94040
Mountain View, California 94040
Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View, California 94040
Mountain View, California 94040
Providence Queen of The Valley
Napa, California 94558
Napa, California 94558
Contact:
Site Public Contact
707-521-3830
Site Public Contact
707-521-3830
USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California 92663
Newport Beach, California 92663
Contact:
Site Public Contact
323-865-0451
Site Public Contact
323-865-0451
Sutter Cancer Research Consortium
Novato, California 94945
Novato, California 94945
Kaiser Permanente Oakland-Broadway
Oakland, California 94611
Oakland, California 94611
Kaiser Permanente-Oakland
Oakland, California 94611
Oakland, California 94611
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California 92868
Orange, California 92868
Palo Alto Medical Foundation Health Care
Palo Alto, California 94301
Palo Alto, California 94301
Kaiser Permanente-Rancho Cordova Cancer Center
Rancho Cordova, California 95670
Rancho Cordova, California 95670
Eisenhower Medical Center
Rancho Mirage, California 92270
Rancho Mirage, California 92270
Contact:
Site Public Contact
760-834-3798
Site Public Contact
760-834-3798
Kaiser Permanente- Marshall Medical Offices
Redwood City, California 94063
Redwood City, California 94063
Contact:
Site Public Contact
877-642-4691
Site Public Contact
877-642-4691
Kaiser Permanente-Richmond
Richmond, California 94801
Richmond, California 94801
Rohnert Park Cancer Center
Rohnert Park, California 94928
Rohnert Park, California 94928
Kaiser Permanente-Roseville
Roseville, California 95661
Roseville, California 95661
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville, California 95661
Roseville, California 95661
Sutter Roseville Medical Center
Roseville, California 95661
Roseville, California 95661
The Permanente Medical Group-Roseville Radiation Oncology
Roseville, California 95678
Roseville, California 95678
Kaiser Permanente Downtown Commons
Sacramento, California 95814
Sacramento, California 95814
Sutter Medical Center Sacramento
Sacramento, California 95816
Sacramento, California 95816
Kaiser Permanente-South Sacramento
Sacramento, California 95823
Sacramento, California 95823
South Sacramento Cancer Center
Sacramento, California 95823
Sacramento, California 95823
California Pacific Medical Center-Pacific Campus
San Francisco, California 94115
San Francisco, California 94115
Kaiser Permanente-San Francisco
San Francisco, California 94115
San Francisco, California 94115
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California 95119
San Jose, California 95119
Kaiser Permanente San Leandro
San Leandro, California 94577
San Leandro, California 94577
Mills Health Center
San Mateo, California 94401
San Mateo, California 94401
Kaiser San Rafael-Gallinas
San Rafael, California 94903
San Rafael, California 94903
Ridley-Tree Cancer Center
Santa Barbara, California 93105
Santa Barbara, California 93105
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California 95051
Santa Clara, California 95051
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California 95065
Santa Cruz, California 95065
Santa Cruz Radiation Oncology Medical Group
Santa Cruz, California 95065
Santa Cruz, California 95065
Kaiser Permanente-Santa Rosa
Santa Rosa, California 95403
Santa Rosa, California 95403
Providence Medical Foundation - Santa Rosa
Santa Rosa, California 95403
Santa Rosa, California 95403
Contact:
Site Public Contact
707-521-3830
Site Public Contact
707-521-3830
Sutter Pacific Medical Foundation
Santa Rosa, California 95403
Santa Rosa, California 95403
Providence Santa Rosa Memorial Hospital
Santa Rosa, California 95405
Santa Rosa, California 95405
Contact:
Site Public Contact
707-521-3830
Site Public Contact
707-521-3830
Kaiser Permanente Cancer Treatment Center
South San Francisco, California 94080
South San Francisco, California 94080
Kaiser Permanente-South San Francisco
South San Francisco, California 94080
South San Francisco, California 94080
Kaiser Permanente-Stockton
Stockton, California 95210
Stockton, California 95210
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, California 94086
Sunnyvale, California 94086
Kaiser Permanente Medical Center-Vacaville
Vacaville, California 95688
Vacaville, California 95688
Kaiser Permanente-Vallejo
Vallejo, California 94589
Vallejo, California 94589
Sutter Solano Medical Center/Cancer Center
Vallejo, California 94589
Vallejo, California 94589
Kaiser Permanente-Walnut Creek
Walnut Creek, California 94596
Walnut Creek, California 94596
Intermountain Health Platte Valley Hospital
Brighton, Colorado 80601
Brighton, Colorado 80601
Cancer Center of Colorado at Sloan's Lake
Denver, Colorado 80204
Denver, Colorado 80204
Contact:
Site Public Contact
303-777-2663
Site Public Contact
303-777-2663
National Jewish Health-Main Campus
Denver, Colorado 80206
Denver, Colorado 80206
Saint Joseph Hospital - Cancer Centers of Colorado
Denver, Colorado 80218
Denver, Colorado 80218
Contact:
Site Public Contact
303-318-3413
Site Public Contact
303-318-3413
Poudre Valley Hospital
Fort Collins, Colorado 80524
Fort Collins, Colorado 80524
Contact:
Site Public Contact
970-297-6150
Site Public Contact
970-297-6150
Cancer Care and Hematology-Fort Collins
Fort Collins, Colorado 80528
Fort Collins, Colorado 80528
Lutheran Hospital - Cancer Centers of Colorado
Golden, Colorado 80401
Golden, Colorado 80401
National Jewish Health-Western Hematology Oncology
Golden, Colorado 80401
Golden, Colorado 80401
Saint Mary's Hospital and Regional Medical Center
Grand Junction, Colorado 81501
Grand Junction, Colorado 81501
UCHealth Greeley Hospital
Greeley, Colorado 80631
Greeley, Colorado 80631
Good Samaritan Hospital - Cancer Centers of Colorado
Lafayette, Colorado 80026
Lafayette, Colorado 80026
Medical Center of the Rockies
Loveland, Colorado 80538
Loveland, Colorado 80538
Contact:
Site Public Contact
970-203-7083
Site Public Contact
970-203-7083
National Jewish Health-Northern Hematology Oncology
Thornton, Colorado 80260
Thornton, Colorado 80260
Intermountain Health Lutheran Hospital
Wheat Ridge, Colorado 80401
Wheat Ridge, Colorado 80401
Hartford HealthCare - Avon
Avon, Connecticut 06001
Avon, Connecticut 06001
Contact:
Site Public Contact
860-972-4700
Site Public Contact
860-972-4700
Hartford Hospital
Hartford, Connecticut 06102
Hartford, Connecticut 06102
Contact:
Site Public Contact
860-545-5363
Site Public Contact
860-545-5363
Hartford HealthCare - Manchester
Manchester, Connecticut 06042
Manchester, Connecticut 06042
Contact:
Site Public Contact
860-972-4700
Site Public Contact
860-972-4700
Midstate Medical Center
Meriden, Connecticut 06451
Meriden, Connecticut 06451
Contact:
Site Public Contact
866-662-5678
Site Public Contact
866-662-5678
The Hospital of Central Connecticut
New Britain, Connecticut 06050
New Britain, Connecticut 06050
Contact:
Site Public Contact
860-224-5660
Site Public Contact
860-224-5660
Beebe Medical Center
Lewes, Delaware 19958
Lewes, Delaware 19958
Beebe South Coastal Health Campus
Millville, Delaware 19967
Millville, Delaware 19967
Helen F Graham Cancer Center
Newark, Delaware 19713
Newark, Delaware 19713
Medical Oncology Hematology Consultants PA
Newark, Delaware 19713
Newark, Delaware 19713
Christiana Care Health System-Christiana Hospital
Newark, Delaware 19718
Newark, Delaware 19718
Beebe Health Campus
Rehoboth Beach, Delaware 19971
Rehoboth Beach, Delaware 19971
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware 19801
Wilmington, Delaware 19801
MedStar Georgetown University Hospital
Washington D.C., District of Columbia 20007
Washington D.C., District of Columbia 20007
Contact:
Site Public Contact
202-444-2223
Site Public Contact
202-444-2223
MedStar Washington Hospital Center
Washington D.C., District of Columbia 20010
Washington D.C., District of Columbia 20010
Contact:
Site Public Contact
202-877-8839
Site Public Contact
202-877-8839
Sibley Memorial Hospital
Washington D.C., District of Columbia 20016
Washington D.C., District of Columbia 20016
George Washington University Medical Center
Washington D.C., District of Columbia 20037
Washington D.C., District of Columbia 20037
Contact:
Site Public Contact
202-741-2210
Site Public Contact
202-741-2210
Mount Sinai Comprehensive Cancer Center at Aventura
Aventura, Florida 33180
Aventura, Florida 33180
Schulze Family Foundation Cancer Clinic - Bonita Health Center
Bonita Springs, Florida 34135
Bonita Springs, Florida 34135
Holy Cross Hospital
Fort Lauderdale, Florida 33308
Fort Lauderdale, Florida 33308
Regional Cancer Center-Lee Memorial Health System
Fort Myers, Florida 33905
Fort Myers, Florida 33905
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida 33021
Hollywood, Florida 33021
Jupiter Medical Center
Jupiter, Florida 33458
Jupiter, Florida 33458
The Watson Clinic
Lakeland, Florida 33805
Lakeland, Florida 33805
Contact:
Site Public Contact
863-680-7780
Site Public Contact
863-680-7780
Mount Sinai Medical Center
Miami Beach, Florida 33140
Miami Beach, Florida 33140
Memorial Hospital West
Pembroke Pines, Florida 33028
Pembroke Pines, Florida 33028
Contact:
Site Public Contact
954-265-4325
Site Public Contact
954-265-4325
Tift Regional Medical Center
Tifton, Georgia 31794
Tifton, Georgia 31794
Contact:
Site Public Contact
800-648-1935
Site Public Contact
800-648-1935
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-532-0315
Site Public Contact
808-532-0315
Queen's Medical Center
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-545-8548
Site Public Contact
808-545-8548
Straub Clinic and Hospital
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-522-4333
Site Public Contact
808-522-4333
Queen's Cancer Center - Kuakini
Honolulu, Hawaii 96817
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-531-8521
Site Public Contact
808-531-8521
Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii 96819
Honolulu, Hawaii 96819
Straub Medical Center - Kahului Clinic
Kahului, Hawaii 96732
Kahului, Hawaii 96732
Hawaii Cancer Care - Westridge
‘Aiea, Hawaii 96701
‘Aiea, Hawaii 96701
Pali Momi Medical Center
‘Aiea, Hawaii 96701
‘Aiea, Hawaii 96701
Contact:
Site Public Contact
808-486-6000
Site Public Contact
808-486-6000
Queen's Cancer Center - Pearlridge
‘Aiea, Hawaii 96701
‘Aiea, Hawaii 96701
Contact:
Site Public Contact
808-487-7447
Site Public Contact
808-487-7447
The Queen's Medical Center - West Oahu
‘Ewa Beach, Hawaii 96706
‘Ewa Beach, Hawaii 96706
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho 83706
Boise, Idaho 83706
Saint Luke's Cancer Institute - Boise
Boise, Idaho 83712
Boise, Idaho 83712
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho 83605
Caldwell, Idaho 83605
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho 83814
Coeur d'Alene, Idaho 83814
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho 83619
Fruitland, Idaho 83619
Idaho Urologic Institute-Meridian
Meridian, Idaho 83642
Meridian, Idaho 83642
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho 83642
Meridian, Idaho 83642
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho 83687
Nampa, Idaho 83687
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho 83687
Nampa, Idaho 83687
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho 83854
Post Falls, Idaho 83854
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho 83864
Sandpoint, Idaho 83864
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho 83301
Twin Falls, Idaho 83301
OSF Saint Anthony's Health Center
Alton, Illinois 62002
Alton, Illinois 62002
Contact:
Site Public Contact
618-463-5623
Site Public Contact
618-463-5623
Rush-Copley Medical Center
Aurora, Illinois 60504
Aurora, Illinois 60504
Advocate Outpatient Center - Aurora
Aurora, Illinois 60506
Aurora, Illinois 60506
Advocate Good Shepherd Hospital
Barrington, Illinois 60010
Barrington, Illinois 60010
Contact:
Site Public Contact
847-842-4847
Site Public Contact
847-842-4847
Illinois CancerCare-Bloomington
Bloomington, Illinois 61704
Bloomington, Illinois 61704
Illinois CancerCare-Canton
Canton, Illinois 61520
Canton, Illinois 61520
Memorial Hospital of Carbondale
Carbondale, Illinois 62902
Carbondale, Illinois 62902
SIH Cancer Institute
Carterville, Illinois 62918
Carterville, Illinois 62918
Illinois CancerCare-Carthage
Carthage, Illinois 62321
Carthage, Illinois 62321
Centralia Oncology Clinic
Centralia, Illinois 62801
Centralia, Illinois 62801
Mount Sinai Hospital Medical Center
Chicago, Illinois 60608
Chicago, Illinois 60608
John H Stroger Jr Hospital of Cook County
Chicago, Illinois 60612
Chicago, Illinois 60612
Contact:
Site Public Contact
312-864-5204
Site Public Contact
312-864-5204
University of Illinois
Chicago, Illinois 60612
Chicago, Illinois 60612
Contact:
Site Public Contact
312-355-3046
Site Public Contact
312-355-3046
University of Chicago Comprehensive Cancer Center
Chicago, Illinois 60637
Chicago, Illinois 60637
Advocate Illinois Masonic Medical Center
Chicago, Illinois 60657
Chicago, Illinois 60657
Contact:
Site Public Contact
773-296-5360
Site Public Contact
773-296-5360
AMG Crystal Lake - Oncology
Crystal Lake, Illinois 60014
Crystal Lake, Illinois 60014
Carle at The Riverfront
Danville, Illinois 61832
Danville, Illinois 61832
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois 62526
Decatur, Illinois 62526
Decatur Memorial Hospital
Decatur, Illinois 62526
Decatur, Illinois 62526
Illinois CancerCare-Dixon
Dixon, Illinois 61021
Dixon, Illinois 61021
Contact:
Site Public Contact
815-285-7800
Site Public Contact
815-285-7800
Advocate Good Samaritan Hospital
Downers Grove, Illinois 60515
Downers Grove, Illinois 60515
Carle Physician Group-Effingham
Effingham, Illinois 62401
Effingham, Illinois 62401
Crossroads Cancer Center
Effingham, Illinois 62401
Effingham, Illinois 62401
Advocate Sherman Hospital
Elgin, Illinois 60123
Elgin, Illinois 60123
Contact:
Site Public Contact
847-429-2907
Site Public Contact
847-429-2907
Illinois CancerCare-Eureka
Eureka, Illinois 61530
Eureka, Illinois 61530
Illinois CancerCare-Galesburg
Galesburg, Illinois 61401
Galesburg, Illinois 61401
Ingalls Memorial Hospital
Harvey, Illinois 60426
Harvey, Illinois 60426
Advocate South Suburban Hospital
Hazel Crest, Illinois 60429
Hazel Crest, Illinois 60429
Contact:
Site Public Contact
708-799-9995
Site Public Contact
708-799-9995
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois 61443
Kewanee, Illinois 61443
AMG Libertyville - Oncology
Libertyville, Illinois 60048
Libertyville, Illinois 60048
Condell Memorial Hospital
Libertyville, Illinois 60048
Libertyville, Illinois 60048
Illinois CancerCare-Macomb
Macomb, Illinois 61455
Macomb, Illinois 61455
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois 61938
Mattoon, Illinois 61938
Trinity Medical Center
Moline, Illinois 61265
Moline, Illinois 61265
Contact:
Site Public Contact
309-779-2000
Site Public Contact
309-779-2000
SSM Health Good Samaritan
Mount Vernon, Illinois 62864
Mount Vernon, Illinois 62864
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois 60451
New Lenox, Illinois 60451
Carle Cancer Institute Normal
Normal, Illinois 61761
Normal, Illinois 61761
Cancer Care Center of O'Fallon
O'Fallon, Illinois 62269
O'Fallon, Illinois 62269
HSHS Saint Elizabeth's Hospital
O'Fallon, Illinois 62269
O'Fallon, Illinois 62269
Advocate Christ Medical Center
Oak Lawn, Illinois 60453-2699
Oak Lawn, Illinois 60453-2699
Contact:
Site Public Contact
800-323-8622
Site Public Contact
800-323-8622
University of Chicago Medicine-Orland Park
Orland Park, Illinois 60462
Orland Park, Illinois 60462
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois 61350
Ottawa, Illinois 61350
Advocate Lutheran General Hospital
Park Ridge, Illinois 60068
Park Ridge, Illinois 60068
Contact:
Site Public Contact
847-384-3621
Site Public Contact
847-384-3621
Illinois CancerCare-Pekin
Pekin, Illinois 61554
Pekin, Illinois 61554
Illinois CancerCare-Peoria
Peoria, Illinois 61615
Peoria, Illinois 61615
Methodist Medical Center of Illinois
Peoria, Illinois 61636
Peoria, Illinois 61636
Illinois CancerCare-Peru
Peru, Illinois 61354
Peru, Illinois 61354
Valley Radiation Oncology
Peru, Illinois 61354
Peru, Illinois 61354
Contact:
Site Public Contact
815-664-4141
Site Public Contact
815-664-4141
Illinois CancerCare-Princeton
Princeton, Illinois 61356
Princeton, Illinois 61356
UW Health Carbone Cancer Center Rockford
Rockford, Illinois 61114
Rockford, Illinois 61114
Southern Illinois University School of Medicine
Springfield, Illinois 62702
Springfield, Illinois 62702
Contact:
Site Public Contact
217-545-7929
Site Public Contact
217-545-7929
Springfield Clinic
Springfield, Illinois 62702
Springfield, Illinois 62702
Contact:
Site Public Contact
800-444-7541
Site Public Contact
800-444-7541
Springfield Memorial Hospital
Springfield, Illinois 62781
Springfield, Illinois 62781
Carle Cancer Center
Urbana, Illinois 61801
Urbana, Illinois 61801
Illinois CancerCare - Washington
Washington, Illinois 61571
Washington, Illinois 61571
Rush-Copley Healthcare Center
Yorkville, Illinois 60560
Yorkville, Illinois 60560
Northwest Cancer Center - Main Campus
Crown Point, Indiana 46307
Crown Point, Indiana 46307
Contact:
Site Public Contact
219-310-2550
Site Public Contact
219-310-2550
UChicago Medicine Northwest Indiana
Crown Point, Indiana 46307
Crown Point, Indiana 46307
Northwest Oncology LLC
Dyer, Indiana 46311
Dyer, Indiana 46311
Contact:
Site Public Contact
219-924-8178
Site Public Contact
219-924-8178
Northwest Cancer Center - Hobart
Hobart, Indiana 46342
Hobart, Indiana 46342
Contact:
Site Public Contact
219-947-1795
Site Public Contact
219-947-1795
Saint Mary Medical Center
Hobart, Indiana 46342
Hobart, Indiana 46342
Saint Catherine Hospital
Indianapolis, Indiana 46312
Indianapolis, Indiana 46312
The Community Hospital
Munster, Indiana 46321
Munster, Indiana 46321
Contact:
Site Public Contact
219-836-3349
Site Public Contact
219-836-3349
Women's Diagnostic Center - Munster
Munster, Indiana 46321
Munster, Indiana 46321
Northwest Cancer Center - Valparaiso
Valparaiso, Indiana 46383
Valparaiso, Indiana 46383
Mary Greeley Medical Center
Ames, Iowa 50010
Ames, Iowa 50010
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
McFarland Clinic - Ames
Ames, Iowa 50010
Ames, Iowa 50010
UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa 50023
Ankeny, Iowa 50023
Contact:
Site Public Contact
515-241-3305
Site Public Contact
515-241-3305
University of Iowa Healthcare Cancer Services Quad Cities
Bettendorf, Iowa 52722
Bettendorf, Iowa 52722
Mercy Hospital
Cedar Rapids, Iowa 52403
Cedar Rapids, Iowa 52403
Contact:
Site Public Contact
319-365-4673
Site Public Contact
319-365-4673
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa 52403
Cedar Rapids, Iowa 52403
Contact:
Site Public Contact
319-363-2690
Site Public Contact
319-363-2690
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa 50325
Clive, Iowa 50325
Contact:
Site Public Contact
515-241-3305
Site Public Contact
515-241-3305
Methodist Jennie Edmundson Hospital
Council Bluffs, Iowa 51503
Council Bluffs, Iowa 51503
Iowa Methodist Medical Center
Des Moines, Iowa 50309
Des Moines, Iowa 50309
Contact:
Site Public Contact
515-241-6727
Site Public Contact
515-241-6727
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa 50309
Des Moines, Iowa 50309
Contact:
Site Public Contact
515-241-3305
Site Public Contact
515-241-3305
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa 50314
Des Moines, Iowa 50314
Contact:
Site Public Contact
515-241-3305
Site Public Contact
515-241-3305
McFarland Clinic - Trinity Cancer Center
Fort Dodge, Iowa 50501
Fort Dodge, Iowa 50501
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa 52242
Iowa City, Iowa 52242
Contact:
Site Public Contact
800-237-1225
Site Public Contact
800-237-1225
McFarland Clinic - Marshalltown
Marshalltown, Iowa 50158
Marshalltown, Iowa 50158
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
UI Healthcare Mission Cancer and Blood - Pella
Pella, Iowa 50219
Pella, Iowa 50219
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa 50263
Waukee, Iowa 50263
Contact:
Site Public Contact
515-241-3305
Site Public Contact
515-241-3305
Central Care Cancer Center - Garden City
Garden City, Kansas 67846
Garden City, Kansas 67846
Central Care Cancer Center - Great Bend
Great Bend, Kansas 67530
Great Bend, Kansas 67530
HaysMed
Hays, Kansas 67601
Hays, Kansas 67601
Contact:
Site Public Contact
785-623-5774
Site Public Contact
785-623-5774
Lawrence Memorial Hospital
Lawrence, Kansas 66044
Lawrence, Kansas 66044
The University of Kansas Cancer Center - Olathe
Olathe, Kansas 66061
Olathe, Kansas 66061
Freeman Physician Group of Pittsburg
Pittsburg, Kansas 66762
Pittsburg, Kansas 66762
Mercy Hospital Pittsburg
Pittsburg, Kansas 66762
Pittsburg, Kansas 66762
Contact:
Site Public Contact
888-446-3729
Site Public Contact
888-446-3729
Salina Regional Health Center
Salina, Kansas 67401
Salina, Kansas 67401
University of Kansas Health System Saint Francis Campus
Topeka, Kansas 66606
Topeka, Kansas 66606
Contact:
Site Public Contact
785-295-8000
Site Public Contact
785-295-8000
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky 40202
Louisville, Kentucky 40202
Contact:
Site Public Contact
502-562-3429
Site Public Contact
502-562-3429
UofL Health Medical Center Northeast
Louisville, Kentucky 40245
Louisville, Kentucky 40245
University Medical Center New Orleans
New Orleans, Louisiana 70112
New Orleans, Louisiana 70112
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland 21287
Baltimore, Maryland 21287
Christiana Care - Union Hospital
Elkton, Maryland 21921
Elkton, Maryland 21921
Boston Medical Center
Boston, Massachusetts 02118
Boston, Massachusetts 02118
Contact:
Site Public Contact
617-638-8265
Site Public Contact
617-638-8265
Dana-Farber Cancer Institute
Boston, Massachusetts 02215
Boston, Massachusetts 02215
Contact:
Site Public Contact
877-442-3324
Site Public Contact
877-442-3324
Dana-Farber Cancer Institute at Boston Medical Center - Brighton
Brighton, Massachusetts 02135
Brighton, Massachusetts 02135
Contact:
Site Public Contact
617-789-2903
Site Public Contact
617-789-2903
Dana-Farber Cancer Institute at Foxborough
Foxborough, Massachusetts 02035
Foxborough, Massachusetts 02035
Contact:
Site Public Contact
877-338-7425
Site Public Contact
877-338-7425
Dana Farber-Merrimack Valley
Methuen, Massachusetts 01844
Methuen, Massachusetts 01844
Contact:
Site Public Contact
877-338-7425
Site Public Contact
877-338-7425
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
Milford, Massachusetts 01757
Milford, Massachusetts 01757
Contact:
Site Public Contact
877-332-4294
Site Public Contact
877-332-4294
Dana-Farber/Brigham and Women's Cancer Center at South Shore
South Weymouth, Massachusetts 02190
South Weymouth, Massachusetts 02190
Contact:
Site Public Contact
781-624-5000
Site Public Contact
781-624-5000
MyMichigan Medical Center Gratiot
Alma, Michigan 48801
Alma, Michigan 48801
MyMichigan Medical Center Alpena
Alpena, Michigan 49707
Alpena, Michigan 49707
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan 48106
Ann Arbor, Michigan 48106
McLaren Cancer Institute-Bay City
Bay City, Michigan 48706
Bay City, Michigan 48706
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan 48114
Brighton, Michigan 48114
Trinity Health Medical Center - Brighton
Brighton, Michigan 48114
Brighton, Michigan 48114
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan 48188
Canton, Michigan 48188
Trinity Health Medical Center - Canton
Canton, Michigan 48188
Canton, Michigan 48188
Chelsea Hospital
Chelsea, Michigan 48118
Chelsea, Michigan 48118
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan 48118
Chelsea, Michigan 48118
Hematology Oncology Consultants-Clarkston
Clarkston, Michigan 48346
Clarkston, Michigan 48346
McLaren Cancer Institute-Clarkston
Clarkston, Michigan 48346
Clarkston, Michigan 48346
Newland Medical Associates-Clarkston
Clarkston, Michigan 48346
Clarkston, Michigan 48346
Corewell Health Dearborn Hospital
Dearborn, Michigan 48124
Dearborn, Michigan 48124
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan 48201
Detroit, Michigan 48201
Henry Ford Health Saint John Hospital
Detroit, Michigan 48236
Detroit, Michigan 48236
Henry Ford River District Hospital
East China Township, Michigan 48054
East China Township, Michigan 48054
OSF Saint Francis Hospital and Medical Group
Escanaba, Michigan 49829
Escanaba, Michigan 49829
Weisberg Cancer Treatment Center
Farmington Hills, Michigan 48334
Farmington Hills, Michigan 48334
Corewell Health Farmington Hills Hospital
Farmington Hills, Michigan 48336
Farmington Hills, Michigan 48336
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Cancer Hematology Centers - Flint
Flint, Michigan 48503
Flint, Michigan 48503
Genesee Hematology Oncology PC
Flint, Michigan 48503
Flint, Michigan 48503
Genesys Hurley Cancer Institute
Flint, Michigan 48503
Flint, Michigan 48503
Hurley Medical Center
Flint, Michigan 48503
Flint, Michigan 48503
McLaren Cancer Institute-Flint
Flint, Michigan 48532
Flint, Michigan 48532
MyMichigan Medical Center Gladwin
Gladwin, Michigan 48624
Gladwin, Michigan 48624
Henry Ford Saint John Hospital - Academic
Grosse Pointe Woods, Michigan 48236
Grosse Pointe Woods, Michigan 48236
Henry Ford Saint John Hospital - Breast
Grosse Pointe Woods, Michigan 48236
Grosse Pointe Woods, Michigan 48236
Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods, Michigan 48236
Grosse Pointe Woods, Michigan 48236
Karmanos Cancer Institute at McLaren Greater Lansing
Lansing, Michigan 48910
Lansing, Michigan 48910
University of Michigan Health - Sparrow Lansing
Lansing, Michigan 48912
Lansing, Michigan 48912
McLaren Cancer Institute-Lapeer Region
Lapeer, Michigan 48446
Lapeer, Michigan 48446
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan 48154
Livonia, Michigan 48154
Henry Ford Saint John Hospital - Macomb Medical
Macomb, Michigan 48044
Macomb, Michigan 48044
Henry Ford Warren Hospital - Breast Macomb
Macomb, Michigan 48044
Macomb, Michigan 48044
MyMichigan Medical Center Midland
Midland, Michigan 48670
Midland, Michigan 48670
McLaren Cancer Institute-Macomb
Mount Clemens, Michigan 48043
Mount Clemens, Michigan 48043
MyMichigan Medical Center Mount Pleasant
Mount Pleasant, Michigan 48858
Mount Pleasant, Michigan 48858
McLaren Cancer Institute-Northern Michigan
Petoskey, Michigan 49770
Petoskey, Michigan 49770
Hope Cancer Center
Pontiac, Michigan 48341
Pontiac, Michigan 48341
Michigan Healthcare Professionals Pontiac
Pontiac, Michigan 48341
Pontiac, Michigan 48341
Newland Medical Associates-Pontiac
Pontiac, Michigan 48341
Pontiac, Michigan 48341
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan 48341
Pontiac, Michigan 48341
McLaren-Port Huron
Port Huron, Michigan 48060
Port Huron, Michigan 48060
Oakland Colon Rectal Associates
Royal Oak, Michigan 48067
Royal Oak, Michigan 48067
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Cancer Care Associates PC
Royal Oak, Michigan 48073
Royal Oak, Michigan 48073
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Comprehensive Medical Center PLLC
Royal Oak, Michigan 48073
Royal Oak, Michigan 48073
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Corewell Health William Beaumont University Hospital
Royal Oak, Michigan 48073
Royal Oak, Michigan 48073
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Hematology Oncology Consultants PC-Royal Oak
Royal Oak, Michigan 48073
Royal Oak, Michigan 48073
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Oakland Medical Group
Royal Oak, Michigan 48073
Royal Oak, Michigan 48073
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
MyMichigan Medical Center Saginaw
Saginaw, Michigan 48601
Saginaw, Michigan 48601
Premier Hematology Oncology Care
Sterling Heights, Michigan 48312
Sterling Heights, Michigan 48312
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
MyMichigan Medical Center Tawas
Tawas City, Michigan 48764
Tawas City, Michigan 48764
Michigan Institute of Urology-Town Center
Troy, Michigan 48084
Troy, Michigan 48084
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Corewell Health Beaumont Troy Hospital
Troy, Michigan 48085
Troy, Michigan 48085
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Hematology Oncology Consultants PC-Troy
Troy, Michigan 48098
Troy, Michigan 48098
Contact:
Site Public Contact
248-551-7695
Site Public Contact
248-551-7695
Henry Ford Health Warren Hospital
Warren, Michigan 48093
Warren, Michigan 48093
Henry Ford Madison Heights Hospital - Breast
Warren, Michigan 48093
Warren, Michigan 48093
Henry Ford Warren Hospital - GLCMS
Warren, Michigan 48093
Warren, Michigan 48093
Huron Gastroenterology PC
Ypsilanti, Michigan 48106
Ypsilanti, Michigan 48106
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan 48197
Ypsilanti, Michigan 48197
Riverwood Healthcare Center
Aitkin, Minnesota 56431
Aitkin, Minnesota 56431
Essentia Health - Baxter Clinic
Baxter, Minnesota 56425
Baxter, Minnesota 56425
Contact:
Site Public Contact
218-828-2880
Site Public Contact
218-828-2880
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota 56601
Bemidji, Minnesota 56601
Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota 56401
Brainerd, Minnesota 56401
Minnesota Oncology - Burnsville
Burnsville, Minnesota 55337
Burnsville, Minnesota 55337
Cambridge Medical Center
Cambridge, Minnesota 55008
Cambridge, Minnesota 55008
Minnesota Oncology Hematology PA-Chaska
Chaska, Minnesota 55318
Chaska, Minnesota 55318
Mercy Hospital
Coon Rapids, Minnesota 55433
Coon Rapids, Minnesota 55433
Minnesota Oncology - Coon Rapids
Coon Rapids, Minnesota 55433
Coon Rapids, Minnesota 55433
Essentia Health - Saint Joseph's Crosslake Clinic
Crosslake, Minnesota 56442
Crosslake, Minnesota 56442
Contact:
Site Public Contact
218-692-1010
Site Public Contact
218-692-1010
Essentia Health - Deer River Clinic
Deer River, Minnesota 56636
Deer River, Minnesota 56636
Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes, Minnesota 56501
Detroit Lakes, Minnesota 56501
Essentia Health Cancer Center
Duluth, Minnesota 55805
Duluth, Minnesota 55805
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota 55805
Duluth, Minnesota 55805
Miller-Dwan Hospital
Duluth, Minnesota 55805
Duluth, Minnesota 55805
Fairview Southdale Hospital
Edina, Minnesota 55435
Edina, Minnesota 55435
Minnesota Oncology - Edina
Edina, Minnesota 55435
Edina, Minnesota 55435
Essentia Health - Ely Clinic
Ely, Minnesota 55731
Ely, Minnesota 55731
Contact:
Site Public Contact
218-365-7900
Site Public Contact
218-365-7900
Essentia Health - Fosston
Fosston, Minnesota 56542
Fosston, Minnesota 56542
Essentia Health Hibbing Clinic
Hibbing, Minnesota 55746
Hibbing, Minnesota 55746
Contact:
Site Public Contact
218-786-3308
Site Public Contact
218-786-3308
Essentia Health - International Falls Clinic
International Falls, Minnesota 56649
International Falls, Minnesota 56649
Contact:
Site Public Contact
218-283-9431
Site Public Contact
218-283-9431
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota 55369
Maple Grove, Minnesota 55369
Minnesota Oncology - Maple Grove
Maple Grove, Minnesota 55369
Maple Grove, Minnesota 55369
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota 55109
Maplewood, Minnesota 55109
Saint John's Hospital - Healtheast
Maplewood, Minnesota 55109
Maplewood, Minnesota 55109
Abbott-Northwestern Hospital
Minneapolis, Minnesota 55407
Minneapolis, Minnesota 55407
Hennepin County Medical Center
Minneapolis, Minnesota 55415
Minneapolis, Minnesota 55415
Health Partners Inc
Minneapolis, Minnesota 55454
Minneapolis, Minnesota 55454
Monticello Cancer Center
Monticello, Minnesota 55362
Monticello, Minnesota 55362
Essentia Health - Moose Lake Clinic
Moose Lake, Minnesota 55767
Moose Lake, Minnesota 55767
Contact:
Site Public Contact
218-485-4481
Site Public Contact
218-485-4481
New Ulm Medical Center
New Ulm, Minnesota 56073
New Ulm, Minnesota 56073
Essentia Health - Park Rapids
Park Rapids, Minnesota 56470
Park Rapids, Minnesota 56470
Essentia Health - Saint Joseph's Pequot Lakes Clinic
Pequot Lakes, Minnesota 56472
Pequot Lakes, Minnesota 56472
Contact:
Site Public Contact
218-568-4416
Site Public Contact
218-568-4416
Essentia Health - Saint Joseph's Pine River Clinic
Pine River, Minnesota 56474
Pine River, Minnesota 56474
Contact:
Site Public Contact
218-587-4416
Site Public Contact
218-587-4416
Fairview Northland Medical Center
Princeton, Minnesota 55371
Princeton, Minnesota 55371
North Memorial Medical Health Center
Robbinsdale, Minnesota 55422
Robbinsdale, Minnesota 55422
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota 56303
Saint Cloud, Minnesota 56303
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota 55416
Saint Louis Park, Minnesota 55416
Regions Hospital
Saint Paul, Minnesota 55101
Saint Paul, Minnesota 55101
United Hospital
Saint Paul, Minnesota 55102
Saint Paul, Minnesota 55102
Essentia Health Sandstone
Sandstone, Minnesota 55072
Sandstone, Minnesota 55072
Saint Francis Regional Medical Center
Shakopee, Minnesota 55379
Shakopee, Minnesota 55379
Essentia Health - Saint Joseph's Staples Clinic
Staples, Minnesota 56479
Staples, Minnesota 56479
Contact:
Site Public Contact
218-894-7870
Site Public Contact
218-894-7870
Lakeview Hospital
Stillwater, Minnesota 55082
Stillwater, Minnesota 55082
Sanford Thief River Falls Medical Center
Thief River Falls, Minnesota 56701
Thief River Falls, Minnesota 56701
Contact:
Site Public Contact
605-312-3320
Site Public Contact
605-312-3320
Essentia Health Virginia Clinic
Virginia, Minnesota 55792
Virginia, Minnesota 55792
Ridgeview Medical Center
Waconia, Minnesota 55387
Waconia, Minnesota 55387
Rice Memorial Hospital
Willmar, Minnesota 56201
Willmar, Minnesota 56201
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota 55125
Woodbury, Minnesota 55125
Sanford Cancer Center Worthington
Worthington, Minnesota 56187
Worthington, Minnesota 56187
Contact:
Site Public Contact
605-312-3320
Site Public Contact
605-312-3320
Fairview Lakes Medical Center
Wyoming, Minnesota 55092
Wyoming, Minnesota 55092
Mercy Oncology and Hematology - Clayton-Clarkson
Ballwin, Missouri 63011
Ballwin, Missouri 63011
Contact:
Site Public Contact
888-446-3729
Site Public Contact
888-446-3729
Central Care Cancer Center - Bolivar
Bolivar, Missouri 65613
Bolivar, Missouri 65613
Cox Cancer Center Branson
Branson, Missouri 65616
Branson, Missouri 65616
Contact:
Site Public Contact
417-269-4520
Site Public Contact
417-269-4520
Mercy Cancer Center - Cape Girardeau
Cape Girardeau, Missouri 63703
Cape Girardeau, Missouri 63703
Contact:
Site Public Contact
888-446-3729
Site Public Contact
888-446-3729
Saint Francis Medical Center
Cape Girardeau, Missouri 63703
Cape Girardeau, Missouri 63703
Parkland Health Center - Farmington
Farmington, Missouri 63640
Farmington, Missouri 63640
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Freeman Health System
Joplin, Missouri 64804
Joplin, Missouri 64804
Mercy Hospital Joplin
Joplin, Missouri 64804
Joplin, Missouri 64804
University Health Truman Medical Center
Kansas City, Missouri 64108
Kansas City, Missouri 64108
Contact:
Site Public Contact
816-404-4375
Site Public Contact
816-404-4375
Lake Regional Hospital
Osage Beach, Missouri 65065
Osage Beach, Missouri 65065
Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri 65401
Rolla, Missouri 65401
Contact:
Site Public Contact
573-458-6379
Site Public Contact
573-458-6379
Phelps Health Delbert Day Cancer Institute
Rolla, Missouri 65401
Rolla, Missouri 65401
Heartland Regional Medical Center
Saint Joseph, Missouri 64506
Saint Joseph, Missouri 64506
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri 63670
Sainte Genevieve, Missouri 63670
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Mercy Hospital Springfield
Springfield, Missouri 65804
Springfield, Missouri 65804
Contact:
Site Public Contact
417-269-4520
Site Public Contact
417-269-4520
CoxHealth South Hospital
Springfield, Missouri 65807
Springfield, Missouri 65807
Contact:
Site Public Contact
417-269-4520
Site Public Contact
417-269-4520
Mercy Infusion Center - Chippewa
St Louis, Missouri 63109
St Louis, Missouri 63109
Contact:
Site Public Contact
888-446-3729
Site Public Contact
888-446-3729
Mercy Hospital South
St Louis, Missouri 63128
St Louis, Missouri 63128
Missouri Baptist Medical Center
St Louis, Missouri 63131
St Louis, Missouri 63131
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Mercy Hospital Saint Louis
St Louis, Missouri 63141
St Louis, Missouri 63141
Contact:
Site Public Contact
314-251-7066
Site Public Contact
314-251-7066
Missouri Baptist Sullivan Hospital
Sullivan, Missouri 63080
Sullivan, Missouri 63080
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
BJC Outpatient Center at Sunset Hills
Sunset Hills, Missouri 63127
Sunset Hills, Missouri 63127
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Mercy Hospital Washington
Washington, Missouri 63090
Washington, Missouri 63090
Contact:
Site Public Contact
636-390-1600
Site Public Contact
636-390-1600
Community Hospital of Anaconda
Anaconda, Montana 59711
Anaconda, Montana 59711
Billings Clinic Cancer Center
Billings, Montana 59101
Billings, Montana 59101
Saint Vincent Frontier Cancer Center
Billings, Montana 59102
Billings, Montana 59102
Contact:
Site Public Contact
800-648-6274
Site Public Contact
800-648-6274
Bozeman Health Deaconess Hospital
Bozeman, Montana 59715
Bozeman, Montana 59715
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana 59701
Butte, Montana 59701
Contact:
Site Public Contact
406-723-2621
Site Public Contact
406-723-2621
Benefis Sletten Cancer Institute
Great Falls, Montana 59405
Great Falls, Montana 59405
Great Falls Clinic
Great Falls, Montana 59405
Great Falls, Montana 59405
Hi-Line Sletten Cancer Center
Havre, Montana 59501
Havre, Montana 59501
Benefis Helena Specialty Center
Helena, Montana 59601
Helena, Montana 59601
Logan Health Medical Center
Kalispell, Montana 59901
Kalispell, Montana 59901
Saint Patrick Hospital - Community Hospital
Missoula, Montana 59802
Missoula, Montana 59802
Community Medical Center
Missoula, Montana 59804
Missoula, Montana 59804
Nebraska Medicine-Bellevue
Bellevue, Nebraska 68123
Bellevue, Nebraska 68123
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
Omaha, Nebraska 68114
Omaha, Nebraska 68114
Contact:
Site Public Contact
402-334-4773
Site Public Contact
402-334-4773
Nebraska Methodist Hospital
Omaha, Nebraska 68114
Omaha, Nebraska 68114
Contact:
Site Public Contact
402-354-5144
Site Public Contact
402-354-5144
Nebraska Medicine-Village Pointe
Omaha, Nebraska 68118
Omaha, Nebraska 68118
Contact:
Site Public Contact
402-559-5600
Site Public Contact
402-559-5600
University of Nebraska Medical Center
Omaha, Nebraska 68198
Omaha, Nebraska 68198
Carson Tahoe Regional Medical Center
Carson City, Nevada 89703
Carson City, Nevada 89703
Cancer and Blood Specialists-Henderson
Henderson, Nevada 89052
Henderson, Nevada 89052
Comprehensive Cancer Centers of Nevada - Henderson
Henderson, Nevada 89052
Henderson, Nevada 89052
Comprehensive Cancer Centers of Nevada-Horizon Ridge
Henderson, Nevada 89052
Henderson, Nevada 89052
OptumCare Cancer Care at Seven Hills
Henderson, Nevada 89052
Henderson, Nevada 89052
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson, Nevada 89074
Henderson, Nevada 89074
Las Vegas Urology - Green Valley
Henderson, Nevada 89074
Henderson, Nevada 89074
Oncology Las Vegas - Henderson
Henderson, Nevada 89074
Henderson, Nevada 89074
Urology Specialists of Nevada - Green Valley
Henderson, Nevada 89074
Henderson, Nevada 89074
OptumCare Cancer Care at Charleston
Las Vegas, Nevada 89102
Las Vegas, Nevada 89102
University Medical Center of Southern Nevada
Las Vegas, Nevada 89102
Las Vegas, Nevada 89102
Hope Cancer Care of Nevada
Las Vegas, Nevada 89103
Las Vegas, Nevada 89103
Radiation Oncology Centers of Nevada Central
Las Vegas, Nevada 89106
Las Vegas, Nevada 89106
Urology Specialists of Nevada - Central
Las Vegas, Nevada 89106
Las Vegas, Nevada 89106
Sunrise Hospital and Medical Center
Las Vegas, Nevada 89109
Las Vegas, Nevada 89109
Las Vegas Prostate Cancer Center
Las Vegas, Nevada 89113
Las Vegas, Nevada 89113
Urology Specialists of Nevada - Southwest
Las Vegas, Nevada 89113
Las Vegas, Nevada 89113
Radiation Oncology Centers of Nevada Southeast
Las Vegas, Nevada 89119
Las Vegas, Nevada 89119
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Las Vegas Urology - Cathedral Rock
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Las Vegas Urology - Smoke Ranch
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Oncology Las Vegas - Tenaya
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
OptumCare Cancer Care at MountainView
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Urology Specialists of Nevada - Northwest
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada 89135
Las Vegas, Nevada 89135
Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas, Nevada 89144
Las Vegas, Nevada 89144
Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas, Nevada 89144
Las Vegas, Nevada 89144
Summerlin Hospital Medical Center
Las Vegas, Nevada 89144
Las Vegas, Nevada 89144
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada 89169
Las Vegas, Nevada 89169
University Cancer Center
Las Vegas, Nevada 89169
Las Vegas, Nevada 89169
Hope Cancer Care of Nevada-Pahrump
Pahrump, Nevada 89048
Pahrump, Nevada 89048
Renown Regional Medical Center
Reno, Nevada 89502
Reno, Nevada 89502
Saint Mary's Regional Medical Center
Reno, Nevada 89503
Reno, Nevada 89503
Radiation Oncology Associates
Reno, Nevada 89509
Reno, Nevada 89509
The Dana-Farber Cancer Institute at Londonderry
Londonderry, New Hampshire 03053
Londonderry, New Hampshire 03053
Jefferson Cherry Hill Hospital
Cherry Hill, New Jersey 08002
Cherry Hill, New Jersey 08002
Sidney Kimmel Cancer Center Washington Township
Sewell, New Jersey 08080
Sewell, New Jersey 08080
New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn, New York 11215
Brooklyn, New York 11215
The New York Hospital Medical Center of Queens
Flushing, New York 11355
Flushing, New York 11355
Glens Falls Hospital
Glens Falls, New York 12801
Glens Falls, New York 12801
Contact:
Site Public Contact
518-926-6700
Site Public Contact
518-926-6700
Northwell Health Cancer Institute at Huntington
Greenlawn, New York 11740
Greenlawn, New York 11740
Contact:
Site Public Contact
516-734-8896
Site Public Contact
516-734-8896
Northwell Health/Center for Advanced Medicine
Lake Success, New York 11042
Lake Success, New York 11042
Contact:
Site Public Contact
516-734-8896
Site Public Contact
516-734-8896
Northern Westchester Hospital
Mount Kisco, New York 10549
Mount Kisco, New York 10549
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York 10032
New York, New York 10032
Manhattan Eye Ear and Throat Hospital
New York, New York 10065
New York, New York 10065
Contact:
Site Public Contact
212-434-4460
Site Public Contact
212-434-4460
NYP/Weill Cornell Medical Center
New York, New York 10065
New York, New York 10065
Contact:
Site Public Contact
212-746-1848
Site Public Contact
212-746-1848
Lenox Hill Hospital
New York, New York 10075
New York, New York 10075
Contact:
Site Public Contact
516-734-8896
Site Public Contact
516-734-8896
Queens Cancer Center
Rego Park, New York 11374
Rego Park, New York 11374
Contact:
Site Public Contact
718-312-3446
Site Public Contact
718-312-3446
University of Rochester
Rochester, New York 14642
Rochester, New York 14642
Contact:
Site Public Contact
585-275-5830
Site Public Contact
585-275-5830
Phelps Memorial Hospital Center
Sleepy Hollow, New York 10591
Sleepy Hollow, New York 10591
Contact:
Site Public Contact
914-366-1600
Site Public Contact
914-366-1600
Montefiore Medical Center-Einstein Campus
The Bronx, New York 10461
The Bronx, New York 10461
Montefiore Medical Center-Weiler Hospital
The Bronx, New York 10461
The Bronx, New York 10461
Wilmot Cancer Institute at Webster
Webster, New York 14580
Webster, New York 14580
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina 27599
Chapel Hill, North Carolina 27599
Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina 28328
Clinton, North Carolina 28328
Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina 27534
Goldsboro, North Carolina 27534
East Carolina University
Greenville, North Carolina 27834
Greenville, North Carolina 27834
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina 28791
Hendersonville, North Carolina 28791
University of North Carolina-Hillsborough Campus
Hillsborough, North Carolina 27278
Hillsborough, North Carolina 27278
Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina 28546
Jacksonville, North Carolina 28546
FirstHealth of the Carolinas-Moore Regional Hospital
Pinehurst, North Carolina 28374
Pinehurst, North Carolina 28374
Sanford Bismarck Medical Center
Bismarck, North Dakota 58501
Bismarck, North Dakota 58501
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota 58103
Fargo, North Dakota 58103
Sanford South University Medical Center
Fargo, North Dakota 58103
Fargo, North Dakota 58103
Contact:
Site Public Contact
701-234-6161
Site Public Contact
701-234-6161
Southpointe-Sanford Medical Center Fargo
Fargo, North Dakota 58103
Fargo, North Dakota 58103
Contact:
Site Public Contact
605-312-3320
Site Public Contact
605-312-3320
Sanford Medical Center Fargo
Fargo, North Dakota 58104
Fargo, North Dakota 58104
Contact:
Site Public Contact
800-437-4010
Site Public Contact
800-437-4010
Sanford Broadway Medical Center
Fargo, North Dakota 58122
Fargo, North Dakota 58122
Sanford Roger Maris Cancer Center
Fargo, North Dakota 58122
Fargo, North Dakota 58122
Essentia Health - Jamestown Clinic
Jamestown, North Dakota 58401
Jamestown, North Dakota 58401
Strecker Cancer Center-Belpre
Belpre, Ohio 45714
Belpre, Ohio 45714
Miami Valley Hospital South
Centerville, Ohio 45459
Centerville, Ohio 45459
Adena Regional Medical Center
Chillicothe, Ohio 45601
Chillicothe, Ohio 45601
Ohio State University Comprehensive Cancer Center
Columbus, Ohio 43210
Columbus, Ohio 43210
Mount Carmel East Hospital
Columbus, Ohio 43213
Columbus, Ohio 43213
The Mark H Zangmeister Center
Columbus, Ohio 43219
Columbus, Ohio 43219
Mount Carmel Health Center West
Columbus, Ohio 43222
Columbus, Ohio 43222
Miami Valley Hospital
Dayton, Ohio 45409
Dayton, Ohio 45409
Premier Blood and Cancer Center
Dayton, Ohio 45409
Dayton, Ohio 45409
Contact:
Site Public Contact
937-276-8320
Site Public Contact
937-276-8320
Miami Valley Hospital North
Dayton, Ohio 45415
Dayton, Ohio 45415
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio 45005-1066
Franklin, Ohio 45005-1066
Central Ohio Breast and Endocrine Surgery
Gahanna, Ohio 43230
Gahanna, Ohio 43230
Miami Valley Cancer Care and Infusion
Greenville, Ohio 45331
Greenville, Ohio 45331
Contact:
Site Public Contact
937-569-7515
Site Public Contact
937-569-7515
Mount Carmel Grove City Hospital
Grove City, Ohio 43123
Grove City, Ohio 43123
Zangmeister Center Grove City
Grove City, Ohio 43123
Grove City, Ohio 43123
Fairfield Medical Center
Lancaster, Ohio 43130
Lancaster, Ohio 43130
Saint Rita's Medical Center
Lima, Ohio 45801
Lima, Ohio 45801
Marietta Memorial Hospital
Marietta, Ohio 45750
Marietta, Ohio 45750
Memorial Hospital
Marysville, Ohio 43040
Marysville, Ohio 43040
Knox Community Hospital
Mount Vernon, Ohio 43050
Mount Vernon, Ohio 43050
Mount Carmel New Albany Surgical Hospital
New Albany, Ohio 43054
New Albany, Ohio 43054
Licking Memorial Hospital
Newark, Ohio 43055
Newark, Ohio 43055
Newark Radiation Oncology
Newark, Ohio 43055
Newark, Ohio 43055
Mercy Health - Perrysburg Hospital
Perrysburg, Ohio 43551
Perrysburg, Ohio 43551
Southern Ohio Medical Center
Portsmouth, Ohio 45662
Portsmouth, Ohio 45662
Springfield Regional Cancer Center
Springfield, Ohio 45504
Springfield, Ohio 45504
Springfield Regional Medical Center
Springfield, Ohio 45504
Springfield, Ohio 45504
Mercy Health - Saint Vincent Hospital
Toledo, Ohio 43608
Toledo, Ohio 43608
Mercy Health - Saint Anne Hospital
Toledo, Ohio 43623
Toledo, Ohio 43623
Mercy Health Sylvania Radiation Oncology Center
Toledo, Ohio 43623
Toledo, Ohio 43623
Upper Valley Medical Center
Troy, Ohio 45373
Troy, Ohio 45373
Saint Ann's Hospital
Westerville, Ohio 43081
Westerville, Ohio 43081
Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center
Wilmington, Ohio 45177
Wilmington, Ohio 45177
Genesis Healthcare System Cancer Care Center
Zanesville, Ohio 43701
Zanesville, Ohio 43701
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma 73104
Oklahoma City, Oklahoma 73104
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma 73120
Oklahoma City, Oklahoma 73120
Contact:
Site Public Contact
405-752-3402
Site Public Contact
405-752-3402
Saint Alphonsus Cancer Care Center-Baker City
Baker City, Oregon 97814
Baker City, Oregon 97814
Saint Charles Health System
Bend, Oregon 97701
Bend, Oregon 97701
Clackamas Radiation Oncology Center
Clackamas, Oregon 97015
Clackamas, Oregon 97015
Bay Area Hospital
Coos Bay, Oregon 97420
Coos Bay, Oregon 97420
Providence Hood River Memorial Hospital
Hood River, Oregon 97031
Hood River, Oregon 97031
Providence Newberg Medical Center
Newberg, Oregon 97132
Newberg, Oregon 97132
Saint Alphonsus Cancer Care Center-Ontario
Ontario, Oregon 97914
Ontario, Oregon 97914
Providence Willamette Falls Medical Center
Oregon City, Oregon 97045
Oregon City, Oregon 97045
Providence Portland Medical Center
Portland, Oregon 97213
Portland, Oregon 97213
Providence Saint Vincent Medical Center
Portland, Oregon 97225
Portland, Oregon 97225
Saint Charles Health System-Redmond
Redmond, Oregon 97756
Redmond, Oregon 97756
Contact:
Site Public Contact
541-706-2909
Site Public Contact
541-706-2909
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania 18103
Allentown, Pennsylvania 18103
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania 18017
Bethlehem, Pennsylvania 18017
Christiana Care Health System-Concord Health Center
Chadds Ford, Pennsylvania 19317
Chadds Ford, Pennsylvania 19317
Geisinger Medical Center
Danville, Pennsylvania 17822
Danville, Pennsylvania 17822
Geisinger Cancer Center Dickson City
Dickson City, Pennsylvania 18519
Dickson City, Pennsylvania 18519
Pocono Medical Center
East Stroudsburg, Pennsylvania 18301
East Stroudsburg, Pennsylvania 18301
Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania 18201
Hazleton, Pennsylvania 18201
Lehigh Valley Hospital-Hazleton
Hazleton, Pennsylvania 18201
Hazleton, Pennsylvania 18201
Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania 17837
Lewisburg, Pennsylvania 17837
Einstein Medical Center Philadelphia
Philadelphia, Pennsylvania 19141
Philadelphia, Pennsylvania 19141
Contact:
Site Public Contact
215-456-3880
Site Public Contact
215-456-3880
Geisinger Cancer Services-Pottsville
Pottsville, Pennsylvania 17901
Pottsville, Pennsylvania 17901
Community Medical Center
Scranton, Pennsylvania 18510
Scranton, Pennsylvania 18510
Reading Hospital
West Reading, Pennsylvania 19611
West Reading, Pennsylvania 19611
Contact:
Site Public Contact
610-988-9323
Site Public Contact
610-988-9323
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania 18711
Wilkes-Barre, Pennsylvania 18711
Asplundh Cancer Pavilion
Willow Grove, Pennsylvania 19090
Willow Grove, Pennsylvania 19090
Medical University of South Carolina
Charleston, South Carolina 29425
Charleston, South Carolina 29425
Avera Cancer Institute-Aberdeen
Aberdeen, South Dakota 57401
Aberdeen, South Dakota 57401
Avera Cancer Institute - Mitchell
Mitchell, South Dakota 57301
Mitchell, South Dakota 57301
Avera Cancer Institute at Pierre
Pierre, South Dakota 57501
Pierre, South Dakota 57501
Rapid City Regional Hospital
Rapid City, South Dakota 57701
Rapid City, South Dakota 57701
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota 57104
Sioux Falls, South Dakota 57104
Avera Cancer Institute
Sioux Falls, South Dakota 57105
Sioux Falls, South Dakota 57105
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota 57117-5134
Sioux Falls, South Dakota 57117-5134
Avera Cancer Institute at Yankton
Yankton, South Dakota 57078
Yankton, South Dakota 57078
Parkland Memorial Hospital
Dallas, Texas 75235
Dallas, Texas 75235
UT Southwestern Simmons Cancer Center - RedBird
Dallas, Texas 75237
Dallas, Texas 75237
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas 75390
Dallas, Texas 75390
Tarrant County Hospital District/JPS Health Network
Fort Worth, Texas 76104
Fort Worth, Texas 76104
UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth, Texas 76104
Fort Worth, Texas 76104
UT Southwestern Clinical Center at Richardson/Plano
Richardson, Texas 75080
Richardson, Texas 75080
Farmington Health Center
Farmington, Utah 84025
Farmington, Utah 84025
University of Utah Sugarhouse Health Center
Salt Lake City, Utah 84106
Salt Lake City, Utah 84106
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah 84112
Salt Lake City, Utah 84112
Central Vermont Medical Center/National Life Cancer Treatment
Berlin Corners, Vermont 05602
Berlin Corners, Vermont 05602
Contact:
Site Public Contact
802-225-5400
Site Public Contact
802-225-5400
University of Vermont Medical Center
Burlington, Vermont 05401
Burlington, Vermont 05401
University of Vermont and State Agricultural College
Burlington, Vermont 05405
Burlington, Vermont 05405
University of Virginia Cancer Center
Charlottesville, Virginia 22908
Charlottesville, Virginia 22908
Inova Schar Cancer Institute
Fairfax, Virginia 22031
Fairfax, Virginia 22031
Inova Fair Oaks Hospital
Fairfax, Virginia 22033
Fairfax, Virginia 22033
Inova Fairfax Hospital
Falls Church, Virginia 22042
Falls Church, Virginia 22042
Centra Alan B Pearson Regional Cancer Center
Lynchburg, Virginia 24501
Lynchburg, Virginia 24501
Virginia Cancer Institute
Richmond, Virginia 23229
Richmond, Virginia 23229
VCU Massey Cancer Center at Stony Point
Richmond, Virginia 23235
Richmond, Virginia 23235
VCU Massey Comprehensive Cancer Center
Richmond, Virginia 23298
Richmond, Virginia 23298
VCU Community Memorial Health Center
South Hill, Virginia 23970
South Hill, Virginia 23970
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington 98520
Aberdeen, Washington 98520
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington 98225
Bellingham, Washington 98225
Providence Regional Cancer System-Centralia
Centralia, Washington 98531
Centralia, Washington 98531
Swedish Cancer Institute-Edmonds
Edmonds, Washington 98026
Edmonds, Washington 98026
Providence Regional Cancer Partnership
Everett, Washington 98201
Everett, Washington 98201
Swedish Cancer Institute-Issaquah
Issaquah, Washington 98029
Issaquah, Washington 98029
Kadlec Clinic Hematology and Oncology
Kennewick, Washington 99336
Kennewick, Washington 99336
Providence Regional Cancer System-Lacey
Lacey, Washington 98503
Lacey, Washington 98503
PeaceHealth Saint John Medical Center
Longview, Washington 98632
Longview, Washington 98632
Skagit Regional Health Cancer Care Center
Mount Vernon, Washington 98274
Mount Vernon, Washington 98274
Valley Medical Center
Renton, Washington 98055
Renton, Washington 98055
Swedish Medical Center-Ballard Campus
Seattle, Washington 98107
Seattle, Washington 98107
Swedish Medical Center-Cherry Hill
Seattle, Washington 98122-5711
Seattle, Washington 98122-5711
Swedish Medical Center-First Hill
Seattle, Washington 98122
Seattle, Washington 98122
PeaceHealth United General Medical Center
Sedro-Woolley, Washington 98284
Sedro-Woolley, Washington 98284
Cancer Care Northwest - Spokane South
Spokane, Washington 99202
Spokane, Washington 99202
Cancer Care Northwest-Valley
Spokane, Washington 99216
Spokane, Washington 99216
Cancer Care Northwest-North Spokane
Spokane, Washington 99218
Spokane, Washington 99218
PeaceHealth Southwest Medical Center
Vancouver, Washington 98664
Vancouver, Washington 98664
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington 99362
Walla Walla, Washington 99362
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima, Washington 98902
Yakima, Washington 98902
West Virginia University Charleston Division
Charleston, West Virginia 25304
Charleston, West Virginia 25304
Contact:
Site Public Contact
304-388-9944
Site Public Contact
304-388-9944
Langlade Hospital and Cancer Center
Antigo, Wisconsin 54409
Antigo, Wisconsin 54409
Duluth Clinic Ashland
Ashland, Wisconsin 54806
Ashland, Wisconsin 54806
Northwest Wisconsin Cancer Center
Ashland, Wisconsin 54806
Ashland, Wisconsin 54806
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin 53105
Burlington, Wisconsin 53105
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin 54729
Chippewa Falls, Wisconsin 54729
Aurora Saint Luke's South Shore
Cudahy, Wisconsin 53110
Cudahy, Wisconsin 53110
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin 54701
Eau Claire, Wisconsin 54701
Aurora Health Care Germantown Health Center
Germantown, Wisconsin 53022
Germantown, Wisconsin 53022
Aurora Cancer Care-Grafton
Grafton, Wisconsin 53024
Grafton, Wisconsin 53024
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin 54301
Green Bay, Wisconsin 54301
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin 54303
Green Bay, Wisconsin 54303
Aurora BayCare Medical Center
Green Bay, Wisconsin 54311
Green Bay, Wisconsin 54311
Essentia Health-Hayward Clinic
Hayward, Wisconsin 54843
Hayward, Wisconsin 54843
Tamarack Health Hayward Medical Center
Hayward, Wisconsin 54843
Hayward, Wisconsin 54843
Contact:
Site Public Contact
218-568-4416
Site Public Contact
218-568-4416
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin 53142
Kenosha, Wisconsin 53142
Gundersen Lutheran Medical Center
La Crosse, Wisconsin 54601
La Crosse, Wisconsin 54601
Marshfield Medical Center - Ladysmith
Ladysmith, Wisconsin 54848
Ladysmith, Wisconsin 54848
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin 54143
Marinette, Wisconsin 54143
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin 54449
Marshfield, Wisconsin 54449
Aspirus Medford Hospital
Medford, Wisconsin 54451
Medford, Wisconsin 54451
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin 53209
Milwaukee, Wisconsin 53209
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin 53215
Milwaukee, Wisconsin 53215
Aurora Sinai Medical Center
Milwaukee, Wisconsin 53233
Milwaukee, Wisconsin 53233
Marshfield Medical Center - Minocqua
Minocqua, Wisconsin 54548
Minocqua, Wisconsin 54548
ProHealth D N Greenwald Center
Mukwonago, Wisconsin 53149
Mukwonago, Wisconsin 53149
Marshfield Medical Center - Neillsville
Neillsville, Wisconsin 54456
Neillsville, Wisconsin 54456
Cancer Center of Western Wisconsin
New Richmond, Wisconsin 54017
New Richmond, Wisconsin 54017
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin 53066
Oconomowoc, Wisconsin 53066
Contact:
Site Public Contact
262-928-7878
Site Public Contact
262-928-7878
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin 54154
Oconto Falls, Wisconsin 54154
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin 54904
Oshkosh, Wisconsin 54904
Aurora Cancer Care-Racine
Racine, Wisconsin 53406
Racine, Wisconsin 53406
Aspirus Cancer Care - James Beck Cancer Center
Rhinelander, Wisconsin 54501
Rhinelander, Wisconsin 54501
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin 54868
Rice Lake, Wisconsin 54868
Saint Vincent Hospital Cancer Center at Sheboygan
Sheboygan, Wisconsin 53081
Sheboygan, Wisconsin 53081
Sheboygan Physicians Group
Sheboygan, Wisconsin 53081
Sheboygan, Wisconsin 53081
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin 53081
Sheboygan, Wisconsin 53081
Essentia Health-Spooner Clinic
Spooner, Wisconsin 54801
Spooner, Wisconsin 54801
Aspirus Cancer Care - Stevens Point
Stevens Point, Wisconsin 54481
Stevens Point, Wisconsin 54481
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin 54482
Stevens Point, Wisconsin 54482
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin 54235-1495
Sturgeon Bay, Wisconsin 54235-1495
Aurora Medical Center in Summit
Summit, Wisconsin 53066
Summit, Wisconsin 53066
Essentia Health Saint Mary's Hospital - Superior
Superior, Wisconsin 54880
Superior, Wisconsin 54880
Contact:
Site Public Contact
701-364-6272
Site Public Contact
701-364-6272
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin 54241
Two Rivers, Wisconsin 54241
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin 53188
Waukesha, Wisconsin 53188
Contact:
Site Public Contact
262-928-7632
Site Public Contact
262-928-7632
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin 53188
Waukesha, Wisconsin 53188
Aspirus Regional Cancer Center
Wausau, Wisconsin 54401
Wausau, Wisconsin 54401
Contact:
Site Public Contact
877-405-6866
Site Public Contact
877-405-6866
Marshfield Clinic-Wausau Center
Wausau, Wisconsin 54401
Wausau, Wisconsin 54401
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin 53226
Wauwatosa, Wisconsin 53226
Aurora West Allis Medical Center
West Allis, Wisconsin 53227
West Allis, Wisconsin 53227
Marshfield Medical Center - Weston
Weston, Wisconsin 54476
Weston, Wisconsin 54476
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin 54494
Wisconsin Rapids, Wisconsin 54494
Contact:
Site Public Contact
715-422-7718
Site Public Contact
715-422-7718
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin 54494
Wisconsin Rapids, Wisconsin 54494
Memorial Hospital of Laramie County
Cheyenne, Wyoming 82001
Cheyenne, Wyoming 82001
Billings Clinic-Cody
Cody, Wyoming 82414
Cody, Wyoming 82414
Cancer Center-Metro Medical Center Bayamon
Bayamón, Puerto Rico 00959-5060
Bayamón, Puerto Rico 00959-5060
Contact:
Site Public Contact
787-395-7085
Site Public Contact
787-395-7085
Puerto Rico Hematology Oncology Group
Bayamón, Puerto Rico 00961
Bayamón, Puerto Rico 00961
Contact:
Site Public Contact
787-780-2865
Site Public Contact
787-780-2865
Doctors Cancer Center
Manatí, Puerto Rico 00674
Manatí, Puerto Rico 00674
Contact:
Site Public Contact
787-621-4397
Site Public Contact
787-621-4397
San Juan Community Oncology Group
San Juan, Puerto Rico 00917
San Juan, Puerto Rico 00917
Contact:
Site Public Contact
787-274-3387
Site Public Contact
787-274-3387
Centro Comprensivo de Cancer de UPR
San Juan, Puerto Rico 00927
San Juan, Puerto Rico 00927
PROncology
San Juan, Puerto Rico 00927
San Juan, Puerto Rico 00927
San Juan City Hospital
San Juan, Puerto Rico 00936
San Juan, Puerto Rico 00936
Contact:
Site Public Contact
787-763-1296
Site Public Contact
787-763-1296
More Details
- Status
- Recruiting
- Sponsor
- Alliance for Clinical Trials in Oncology
Detailed Description
PRIMARY OBJECTIVE: I. To determine if overall survival (OS) is improved in patients who received mFOLFIRINOX +/- nivolumab in comparison to FOLFOX +/- nivolumab as first-line chemotherapy for metastatic gastroesophageal adenocarcinoma. SECONDARY OBJECTIVES: I. To compare other indices of efficacy, including progression-free survival, objective response rates and duration of response between both treatment arms. II. To evaluate safety and tolerability associated with treatment in each of the treatment arms. III. To evaluate the proportion of patients receiving second line of therapy in both arms. IV. To evaluate tolerability of the treatment in both arms using Patient Reported Outcomes-Common Terminology Criteria for Adverse Events (PRO-CTCAE). EXPLORATORY OBJECTIVES: I. Exploratory correlative markers will also be measured and evaluated within and between arms to better assess mechanisms and prognostic impact of markers on impact. These will include baseline PD-L1 combined positive score (CPS) and cell free deoxyribonucleic acid (cfDNA) before and after treatment. II. To evaluate and assess the feasibility and compliance associated with not centrally collecting perceived attribution of protocol treatment to reported adverse events. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients receive fluorouracil intravenously (IV), leucovorin calcium IV, oxaliplatin IV, and irinotecan IV on study and nivolumab IV as clinically indicated. Patients undergo magnetic resonance imaging (MRI) and a computed tomography (CT) scan throughout the trial. Patients may also undergo blood sample collection on study. ARM II: Patients receive fluorouracil IV, leucovorin calcium IV, and oxaliplatin IV on study and nivolumab IV as clinically indicated. Patients undergo MRI and a CT scan throughout the trial. Patients may also undergo blood sample collection on study.