Impact of Sleep Restriction on Blood Pressure Reactivity
Purpose
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
Conditions
- Sleep
- Blood Pressure
Eligibility
- Eligible Ages
- Between 18 Years and 45 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Healthy adult men and women - 18-45 years of age - BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group) - Non-pregnant, non-breastfeeding, and non-nicotine users - Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight - Premenopausal
Exclusion Criteria
- No acute or chronic conditions - Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function - Self-reported history of irregular sleep - Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Non-Randomized
- Intervention Model
- Crossover Assignment
- Primary Purpose
- Basic Science
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Sleep Restriction |
You will be asked to shorten your sleep to four hours. |
|
|
No Intervention Normal Sleep |
You will be asked to sleep for 7-9 hours. |
|
Recruiting Locations
University of Missouri
Columbia, Missouri 65211
Columbia, Missouri 65211
More Details
- Status
- Recruiting
- Sponsor
- University of Missouri-Columbia