Evaluation of Muscle Oxygen With MRI
Purpose
Demonstration of soft tissue hypoxia on MRI using external compression and muscle contraction.
Condition
- Muscle Oxygenation
Eligibility
- Eligible Ages
- Between 20 Years and 64 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Alert and oriented. - Able to lift 10lbs. and hold for 30 seconds - Not claustrophobic. - Intact sensation in right upper extremity.
Exclusion Criteria
- Latex allergy or allergy to isopropyl alcohol. - Skin injury or decreased sensation on right upper extremity.
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- N/A
- Intervention Model
- Single Group Assignment
- Primary Purpose
- Basic Science
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental MRI |
Participant will undergo a single MRI examination of arm with no contrast. |
|
Recruiting Locations
Mount Sinai Hess Center
New York, New York 10029
New York, New York 10029
More Details
- Status
- Recruiting
- Sponsor
- Icahn School of Medicine at Mount Sinai
Detailed Description
Participant will undergo a single MRI examination. Standard orthopedic Sarmiento brace/ shell applied to participant's arm. Inside the brace will be a standard blood pressure cuff with a standard brace soft foam attached; blood pressure cuff will be partially inflated. Participant will also be asked to lift MRI compatible 10 lb. weight. Muscle oxygenation will be actively measured using MRI. No medications are being given, and no invasive devices are being used.